U.S. Route 222 is a U.S. Highway that is a spur of US 22 in the states of Maryland and Pennsylvania. It runs for 95 miles (153 km) from US 1 in Conowingo, Maryland, north to the junction of Interstate 78 (I-78) and Pennsylvania Route 309 in Dorneyville, Pennsylvania. US 222 is almost entirely in Pennsylvania, and serves as the state's principal artery between the Lancaster and Reading areas in the west and the Lehigh Valley in the east.
U.S. Route 422 (US 422) is a 271-mile-long (436 km) spur route of US 22 split into two segments in the U.S. states of Ohio and Pennsylvania. The western segment of US 422 runs from downtown Cleveland, Ohio, east to Ebensburg, Pennsylvania. The eastern segment, located entirely within Pennsylvania, runs from Hershey east to King of Prussia, near Philadelphia. US 422 Business serves as a business route into each of four towns along the way.
Pennsylvania Route 29 is a 118-mile-long (190 km) north–south state highway that runs through most of eastern Pennsylvania.
Pennsylvania Route 724 is a 30-mile (48 km) road in the U.S. commonwealth of Pennsylvania that runs from U.S. Route 422 in Sinking Spring southeast to PA 23 near Phoenixville. PA 724 travels through Berks and Chester counties. The route runs through the southern suburbs of Reading, passing through Shillington and Kenhorst. Past the Reading area, PA 724 continues southeast parallel to the Schuylkill River, passing through or near Birdsboro, Pottstown, and Spring City. The route intersects many roads including US 222 near Shillington, PA 10 and Interstate 176 (I-176) southeast of Reading, PA 345 in Birdsboro, and PA 100 and US 422 near Pottstown.
Pennsylvania Route 363 (PA 363) is a state highway located in Montgomery County, Pennsylvania that is a spur of PA 63. The route, which is signed north-south, runs 11.96 mi (19.25 km) from an interchange with U.S. Route 422 (US 422) in Audubon northeast to an intersection with PA 63 in Lansdale. The route runs mostly through suburban areas of central Montgomery County, passing some farmland in Worcester Township. PA 363 is designated along Trooper Road, Ridge Pike, Park Avenue, and Valley Forge Road. In the community of Worcester, the route crosses PA 73.
Pennsylvania Route 72 is a 37.8-mile-long (60.8 km) north–south state route located in southeast Pennsylvania. The southern terminus of the route is at U.S. Route 222 /PA 272 in Lancaster. The northern terminus is at PA 443 north of Lickdale in Union Township. PA 72 serves as a major road connecting Lancaster and Lebanon counties, serving East Petersburg, Manheim, Cornwall, Lebanon, and Jonestown. The route intersects several major roads including US 30 and PA 283 north of Lancaster, the Pennsylvania Turnpike south of Cornwall, US 322 along a concurrency on a freeway bypassing Cornwall, US 422 in Lebanon, US 22 near Jonestown, and I-81 via Fisher Avenue in Lickdale.
Pennsylvania Route 25 is a 35-mile-long (56 km) state highway located in Dauphin and Schuylkill counties in central Pennsylvania. The western terminus of the route is at U.S. Route 209 in Millersburg. The eastern terminus is at US 209 in Newtown. PA 25 runs parallel to the Mahantongo Mountains and the Mahantango Valley, as well as US 209, for its entire length. The route passes through the communities of Berrysburg, Gratz, Sacramento, and Hegins. PA 25 intersects PA 225 in Berrysburg, PA 125 in Hegins, and Interstate 81 (I-81) in Frailey Township. PA 25 was designated in 1928 to run from US 209 in Millersburg east to PA 443 in Pine Grove, running east to Hegins before heading southeast to Tremont and south to Pine Grove. The road between Hegins and Newtown was designated as PA 125. PA 25 was realigned to head east from Hegins to Newtown in the 1930s, with the former alignment between Pine Grove and Hegins becoming a relocated PA 125.
Pennsylvania Route 10 is a 44.04-mile-long (70.88 km) state route in southeastern Pennsylvania. Its southern terminus is at PA 472 in Oxford. Its northern terminus is at U.S. Route 222 Business in Reading. PA 10 is mostly a two-lane undivided road that serves Chester, Lancaster, and Berks counties. The route begins in Oxford and passes through rural areas of western Chester County, serving Cochranville, Parkesburg, Compass, and Honey Brook. The route passes through a small corner of eastern Lancaster County before it enters Berks County and reaches Morgantown, where it has interchanges with Interstate 176 (I-176) and the Pennsylvania Turnpike (I-76). Between Morgantown and Reading, PA 10 parallels I-176.
Pennsylvania Route 12 (PA 12) is a 9.566-mile-long (15.395 km) state highway located in Berks County in eastern Pennsylvania. The western terminus of the route is at U.S. Route 222 (US 222) and US 422 in Wyomissing. Its eastern terminus is PA 662 in the community of Pricetown in Ruscombmanor Township. In the Reading area, PA 12 is a four-lane freeway called the Warren Street Bypass that heads northeast through urban areas, coming to interchanges with multiple roads including PA 183, PA 61, and US 222 Business (US 222 Bus.). In Alsace Township, the route becomes a two-lane undivided road with at-grade intersections called Pricetown Road and continues northeast through rural areas, intersecting PA 73 before ending at PA 662.
Pennsylvania Route 441 is a 32-mile-long (51 km) state route that is located in central Pennsylvania in the United States. It primarily parallels the Susquehanna River through Lancaster and Dauphin counties.
U.S. Route 222 Business is a 12.17-mile (19.59 km) business route of US 222 in Reading, Pennsylvania. The southern terminus is at US 222 in Cumru Township. Its northern terminus is at US 222 in Ontelaunee Township. The route begins at the US 222 freeway and heads through the southwestern suburbs of Reading as Lancaster Avenue, intersecting Pennsylvania Route 724 in Shillington. US 222 Bus. continues into Reading on Lancaster Avenue and intersects the northern termini of PA 625 and PA 10 before reaching an interchange with the US 422 freeway.
Pennsylvania Route 501 is a north–south state highway in south central Pennsylvania that runs for 38.7 miles (62.3 km). Its southern terminus is at U.S. Route 222 and PA 272 north of Lancaster, and its northern terminus is PA 895 southeast of Pine Grove. The route heads north from Lancaster and runs through suburban and rural areas in northern Lancaster County, passing through Lititz and crossing US 322 in Brickerville. PA 501 continues into Lebanon County and heads into the Lebanon Valley, where it passes through Schaefferstown and intersects US 422 in Myerstown. The route passes through western Berks County, where it has an interchange with Interstate 78 (I-78)/US 22 near the community of Bethel. PA 501 crosses Blue Mountain into Schuylkill County and continues to its northern terminus.
Pennsylvania Route 183 (PA 183) is a 31.7-mile-long (51.0 km) route that runs north to south in southeastern Pennsylvania. The southern terminus is at U.S. Route 422 Business in Reading in Berks County. Its northern terminus is at PA 61 near Schuylkill Haven in Schuylkill County. The road passes through developed areas near Reading before continuing north through rural areas, crossing from Berks County into Schuylkill County at Blue Mountain. PA 183 serves the communities of Bernville, Strausstown, and Cressona.
Pennsylvania Route 443 is an 80-mile-long (130 km) east–west state highway in the US state of Pennsylvania. The western terminus is at an intersection with State Route 3009 at North Front Street on the east bank of the Susquehanna River in the community of Fort Hunter in Middle Paxton Township, just west of an interchange with the U.S. Route 22 /US 322 freeway. The eastern terminus is at US 209 in Lehighton. The route runs through rural areas in the Ridge-and-Valley Appalachians in Dauphin, Lebanon, Schuylkill, and Carbon counties, serving Fort Indiantown Gap, Pine Grove, Schuylkill Haven, Orwigsburg, New Ringgold, and South Tamaqua. PA 443 intersects several major roads, including US 22/US 322 near its western terminus, PA 72 in Union Township, Interstate 81 (I-81) near Pine Grove, PA 61 between Schuylkill Haven and Orwigsburg, and PA 309 in South Tamaqua.
Interstate 78 (I-78) is a major east–west Interstate Highway stretching from Union Township, Lebanon County, Pennsylvania, in the west to the Holland Tunnel and New York City in the east. In Pennsylvania, I-78 runs for about 78 miles (126 km) from the western terminus at I-81 in Union Township east to the New Jersey state line near Easton in Northampton County.
Pennsylvania Route 343 is an 8.16-mile (13.13 km) route running from Lebanon north to Fredericksburg in Lebanon County, Pennsylvania. It begins at PA 72 and ends at Exit 6 of Interstate 78 (I-78). PA 343 heads mostly through urbanized areas near Lebanon before continuing into rural areas further north. There is a concurrency with U.S. Route 22 near the northern terminus.
Pennsylvania Route 419 is a state highway in the U.S. state of Pennsylvania. The route runs from U.S. Route 322 in West Cornwall Township, Lebanon County north to PA 183 in Bethel Township, Berks County. The route heads east from US 322 through Quentin and Cornwall to Schaefferstown, where it turns east and passes through Newmanstown. PA 419 enters Berks County and passes through Womelsdorf, where it comes to a junction with US 422. From the route, the route continues north and passes through Rehrersburg and has an interchange with Interstate 78 (I-78)/US 22 near Schubert before coming to its northern terminus. PA 419 is a two-lane undivided road its entire length and passes through rural areas. The portion of the route in Lebanon County is designated the Lebanon Cornwall Scenic Byway, a Pennsylvania Scenic Byway.
Pennsylvania Route 737 (PA 737) is a state highway in Berks County, Pennsylvania. The route runs from U.S. Route 222 (US 222) in the borough of Kutztown north to PA 143 in Albany Township. PA 737 heads north from an interchange with US 222 north of Kutztown on Krumsville Road. It continues north through a small part of Maxatawny Township into Greenwich Township. The road features an interchange with Interstate 78 (I-78)/US 22 in the village of Krumsville. PA 737 then heads northwest into Albany Township, where it ends at PA 143 near the village of Kempton.
Pennsylvania Route 339 is a 32.8-mile-long (52.8 km) north–south state highway located in Schuylkill, Columbia, and Luzerne counties in Pennsylvania. The southern terminus is at PA 54 in Mahanoy City. The northern terminus is at PA 93 in Nescopeck. The route is a two-lane road that passes through mountainous areas in the eastern part of the state. PA 339 runs north through the Coal Region to Brandonville, where it heads northwest to follow the Catawissa Creek to Mainville. From Mainville, the route passes through farmland to Mifflinville, where it follows the Susquehanna River to Nescopeck. PA 339 forms a concurrency with PA 924 in Brandonville and has an interchange with Interstate 80 (I-80) in Mifflinville.
Frystown is a census-designated place in Bethel Township, in far western Berks County, Pennsylvania, United States. It is located near the township line with Tulpehocken Township. The community is served by the Tulpehocken Area School District. As of the 2010 census, the population was 380 residents. The Little Swatara Creek forms the natural southern boundary of Frystown and flows westward into the Swatara Creek, a tributary of the Susquehanna River. Interstate 78 has an interchange with Route 645 in Frystown. The CDP is split between the Myerstown and Bethel post offices, which use the ZIP codes of 17067 and 19507, respectively.
US 422 in Myerstown 
I-78 / US 22 in Bethel Township 
PA 443 in Pine Grove Township 
