Phenamidine

Phenamidine
Clinical data
Trade names	Oxopirvedine
Other names	4,4'-Diamidinodiphenyl ether; 4,4'-Oxydibenzamidine
ATCvet code	QP51AF03 ( WHO );
Identifiers
	IUPAC name 4,4’-Oxydibenzenecarboximidamide;
CAS Number	101-62-2 ;
PubChem CID	64948 ;
ChemSpider	58474 ;
UNII	382086V7IB ;
CompTox Dashboard (EPA)	DTXSID10143619 ;
ECHA InfoCard	100.002.692
Chemical and physical data
Formula	C14H14N4O
Molar mass	254.293 g·mol−1
3D model (JSmol)	Interactive image ;
Melting point	215 to 216 °C (419 to 421 °F)
	SMILES O(c1ccc(C(=[N@H])N)cc1)c2ccc(cc2)C(=[N@H])N;
	InChI InChI=1S/C14H14N4O/c15-13(16)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(17)18/h1-8H,(H3,15,16)(H3,17,18); Key:DMABBVCVVXMJDH-UHFFFAOYSA-N;

Last updated January 11, 2026

Phenamidine is an antiprotozoal drug of the amidine class used in veterinary medicine. It is used to treat Babesia infection (babesiosis) dogs, horses, and cattle.^[1]^[2] Because the drug causes frequent allergic reactions, it is usually combined with an antihistamine.^[3]

References

1 2 Merck Index , 11th Edition, 7165
↑ Randall JB, Laws SG (May 1947). "Phenamidine in the treatment of Babesia bigemina infections of cattle". Annals of Tropical Medicine and Parasitology. 41 (1): 39–42. doi:10.1080/00034983.1947.11685310. PMID 20249289.
↑ Benchchem

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[Merck-1] 1 2 Merck Index , 11th Edition, 7165

[pmid20249289-2] Randall JB, Laws SG (May 1947). "Phenamidine in the treatment of Babesia bigemina infections of cattle". Annals of Tropical Medicine and Parasitology. 41 (1): 39–42. doi:10.1080/00034983.1947.11685310. PMID 20249289.

[3] Benchchem

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