The Apicomplexa are organisms of a large phylum of mainly parasitic alveolates. Most possess a unique form of organelle structure that comprises a type of (non-photosynthetic) plastid called an apicoplast—with an apical complex membrane. The organelle's apical shape is an adaptation that the apicomplexan applies in penetrating a host cell.
Plasmodium is a genus of unicellular eukaryotes that are obligate parasites of vertebrates and insects. The life cycles of Plasmodium species involve development in a blood-feeding insect host which then injects parasites into a vertebrate host during a blood meal. Parasites grow within a vertebrate body tissue before entering the bloodstream to infect red blood cells. The ensuing destruction of host red blood cells can result in malaria. During this infection, some parasites are picked up by a blood-feeding insect, continuing the life cycle.
Plasmodium knowlesi is a parasite that causes malaria in humans and other primates. It is found throughout Southeast Asia, and is the most common cause of human malaria in Malaysia. Like other Plasmodium species, P. knowlesi has a life cycle that requires infection of both a mosquito and a warm-blooded host. While the natural warm-blooded hosts of P. knowlesi are likely various Old World monkeys, humans can be infected by P. knowlesi if they are fed upon by infected mosquitoes. P. knowlesi is a eukaryote in the phylum Apicomplexa, genus Plasmodium, and subgenus Plasmodium. It is most closely related to the human parasite Plasmodium vivax as well as other Plasmodium species that infect non-human primates.
Plasmodium aegyptensis is a parasite of the genus Plasmodium subgenus Vinckeia which infects the Egyptian grass rat. The insect vector(s) for this species is not yet known.
Plasmodium azurophilum is a species of the genus Plasmodium. Like all species in this genus it is a parasite of both vertebrates and insects. The vertebrate hosts are anole lizards.
Plasmodium brumpti is a parasite of the genus Plasmodium subgenus Sauramoeba. As in all Plasmodium species, P. brumpti has both vertebrate and insect hosts. The vertebrate hosts for this parasite are reptiles.
Plasmodium chiricahuae is a parasite of the genus Plasmodium subgenus Paraplasmodium.
Plasmodium floridense is a parasite of the genus Plasmodium subgenus Lacertaemoba. As in all Plasmodium species, P. floridense has both vertebrate and insect hosts. The vertebrate hosts for this parasite are lizards.
Plasmodium eylesi is a parasite of the genus Plasmodium subgenus Plasmodium.
Plasmodium giganteum is a parasite of the genus Plasmodium subgenus Sauramoeba. As in all Plasmodium species, P. giganteum has both vertebrate and insect hosts. The vertebrate hosts for this parasite are reptiles.
Plasmodium basilisci is a parasite of the genus Plasmodium subgenus Carinamoeba.
Plasmodium mexicanum is a parasite of the genus Plasmodium subgenus Paraplasmodium.
Plasmodium loveridgei is a parasite of the genus Plasmodium subgenus Lacertamoeba.
Plasmodium minuoviride is a parasite of the genus Plasmodium.
Plasmodium neusticuri is a parasite of the genus Plasmodium.
Plasmodium gonatodi is a parasite of the genus Plasmodium.
Hematozoa is a subclass of blood parasites of the Apicomplexa clade. Well known examples include the Plasmodium spp. which cause malaria in humans and Theileria which causes theileriosis in cattle. A large number of species are known to infect birds and are transmitted by insect vectors. The pattern in which Haematozoa infect a host cell depends on the genera of the blood parasite. Plasmodium and Leucozytozoon displace the nucleus of the host cell so that the parasite can take control of the cell where as Hemoproteus completely envelops the nucleus in a host cell.
Plasmodium cynomolgi is an apicomplexan parasite that infects mosquitoes and Asian Old World monkeys. In recent years, a number of natural infections of humans have also been documented. This species has been used as a model for human Plasmodium vivax because Plasmodium cynomolgi shares the same life cycle and some important biological features with P. vivax.
Plasmodium scelopori is a parasite of the genus Plasmodium subgenus Carinamoeba.
