Postmortem caloricity

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Postmortem caloricity is a phenomenon where the body temperature of a corpse rises or remains unusually high for up to 2 hours after death instead of falling.

Contents

Cause

Postmortem caloricity may (more frequently) be observed in deaths resulting from asphyxia [ citation needed ], poisonings (e.g. with datura [ citation needed ], alcohol, strychnine), sepsis, bacteraemia, and infectious diseases (yellow fever, [1] rabies, rheumatic fever, cholera, tetanus, smallpox), meningitis, peritonitis, nephritis, brain stem haemorrhages (especially pontine haemorrhages), intracranial injuries, liver abscesses, sunstroke, etc.

According to Robert G. Mayer, author of the seminal "Embalming: History, Theory and Practice", postmortem caloricity is a "rise in temperature after death due to continued cellular oxidation." In mortuary science, there are two phases of death—somatic and cellular. Somatic death is the cessation of the tripod of life, meaning the failure of circulation, respiration, or cerebral activity. Cellular death continues long after somatic death, with the classic resulting condition of rigor mortis (stiffening of the muscles due to lack of oxygen and increase in lactic acids). Postmortem changes are also attributable to the activity of enzymes and not simply bacteria. As such, postmortem caloricity is a postmortem cellular phenomenon associated with cellular oxidation. Postmortem caloricity is a purely chemical reaction and has no relation to microbial activity, similar to rigor mortis, algor mortis (postmortem cooling of the body), and livor mortis (settling of blood to dependent parts of the body due to gravity). Postmortem caloricity is a fairly rare phenomenon and while statistical data is unavailable in the literature, any experienced embalmer, coroner, or medical examiner will affirm that it is atypical regarding cellular death.

Mechanism

Postmortem heat production is caused by biochemical and microbial activity in the dead body. The cause of postmortem caloricity varies depending on the cause of death:

The corpse may also absorb heat from the environment when environmental temperature exceeds that of the body.

Related Research Articles

<span class="mw-page-title-main">Fever</span> Raised body temperature due to disease

Fever or pyrexia in humans is a symptom of organism's anti-infection defense mechanism that appears with body temperature exceeding the normal range due to an increase in the body's temperature set point in the hypothalamus. There is no single agreed-upon upper limit for normal temperature: sources use values ranging between 37.2 and 38.3 °C in humans.

<span class="mw-page-title-main">Forensic pathology</span> Medical speciality

Forensic pathology is pathology that focuses on determining the cause of death by examining a corpse. A post mortem examination is performed by a medical examiner or forensic pathologist, usually during the investigation of criminal law cases and civil law cases in some jurisdictions. Coroners and medical examiners are also frequently asked to confirm the identity of remains.

<span class="mw-page-title-main">Hyperthermia</span> Elevated body temperature due to failed thermoregulation

Hyperthermia, also known simply as overheating, is a condition in which an individual's body temperature is elevated beyond normal due to failed thermoregulation. The person's body produces or absorbs more heat than it dissipates. When extreme temperature elevation occurs, it becomes a medical emergency requiring immediate treatment to prevent disability or death. Almost half a million deaths are recorded every year from hyperthermia.

Rigor mortis, or postmortem rigidity, is the fourth stage of death. It is one of the recognizable signs of death, characterized by stiffening of the limbs of the corpse caused by chemical changes in the muscles postmortem. In humans, rigor mortis can occur as soon as four hours after death. Contrary to folklore and common belief, rigor mortis is not permanent and begins to pass within hours of onset. Typically, it lasts no longer than eight hours at "room temperature".

<span class="mw-page-title-main">Strychnine</span> Poisonous substance used as pesticide

Strychnine is a highly toxic, colorless, bitter, crystalline alkaloid used as a pesticide, particularly for killing small vertebrates such as birds and rodents. Strychnine, when inhaled, swallowed, or absorbed through the eyes or mouth, causes poisoning which results in muscular convulsions and eventually death through asphyxia. While it is no longer used medicinally, it was used historically in small doses to strengthen muscle contractions, such as a heart and bowel stimulant and performance-enhancing drug. The most common source is from the seeds of the Strychnos nux-vomica tree.

<span class="mw-page-title-main">Decomposition</span> Process in which organic substances are broken down into simpler organic matter

Decomposition or rot is the process by which dead organic substances are broken down into simpler organic or inorganic matter such as carbon dioxide, water, simple sugars and mineral salts. The process is a part of the nutrient cycle and is essential for recycling the finite matter that occupies physical space in the biosphere. Bodies of living organisms begin to decompose shortly after death. Animals, such as earthworms, also help decompose the organic materials. Organisms that do this are known as decomposers or detritivores. Although no two organisms decompose in the same way, they all undergo the same sequential stages of decomposition. The science which studies decomposition is generally referred to as taphonomy from the Greek word taphos, meaning tomb. Decomposition can also be a gradual process for organisms that have extended periods of dormancy.

Putrefaction is the fifth stage of death, following pallor mortis, livor mortis, algor mortis, and rigor mortis. This process references the breaking down of a body of an animal post-mortem. In broad terms, it can be viewed as the decomposition of proteins, and the eventual breakdown of the cohesiveness between tissues, and the liquefaction of most organs. This is caused by the decomposition of organic matter by bacterial or fungal digestion, which causes the release of gases that infiltrate the body's tissues, and leads to the deterioration of the tissues and organs. The approximate time it takes putrefaction to occur is dependent on various factors. Internal factors that affect the rate of putrefaction include the age at which death has occurred, the overall structure and condition of the body, the cause of death, and external injuries arising before or after death. External factors include environmental temperature, moisture and air exposure, clothing, burial factors, and light exposure. Body farms are facilities that study the way various factors affect the putrefaction process.

Algor mortis, the third stage of death, is the change in body temperature post mortem, until the ambient temperature is matched. This is generally a steady decline, although if the ambient temperature is above the body temperature, the change in temperature will be positive, as the (relatively) cooler body equalizes with the warmer environment. External factors can have a significant influence.

Coffin birth, also known as postmortem fetal extrusion, is the expulsion of a nonviable fetus through the vaginal opening of the decomposing body of a deceased pregnant woman due to increasing pressure from intra-abdominal gases. This kind of postmortem delivery occurs very rarely during the decomposition of a body. The practice of chemical preservation, whereby chemical preservatives and disinfectant solutions are pumped into a body to replace natural body fluids, have made the occurrence of "coffin birth" so rare that the topic is rarely mentioned in international medical discourse.

<span class="mw-page-title-main">Post-mortem interval</span> Time that has elapsed since a person has died

The post-mortem interval (PMI) is the time that has elapsed since an individual's death. When the time of death is not known, the interval may be estimated, and so an approximate time of death established. Postmortem interval estimations can range from hours, to days or even years depending on the type of evidence present. There are standard medical and scientific techniques supporting such an estimation.

Cadaveric spasm, also known as postmortem spasm, instantaneous rigor mortis, cataleptic rigidity, or instantaneous rigidity, is a rare form of muscular stiffening that occurs at the moment of death and persists into the period of rigor mortis. Cadaveric spasm can be distinguished from rigor mortis as the former is a stronger stiffening of the muscles that cannot be easily undone, while rigor mortis can.

Normal human body temperature is the typical temperature range found in humans. The normal human body temperature range is typically stated as 36.5–37.5 °C (97.7–99.5 °F).

<span class="mw-page-title-main">Strychnine poisoning</span> Medical condition

Strychnine poisoning can be fatal to humans and other animals and can occur by inhalation, swallowing or absorption through eyes or mouth. It produces some of the most dramatic and painful symptoms of any known toxic reaction, making it quite noticeable and a common choice for assassinations and poison attacks. For this reason, strychnine poisoning is often portrayed in literature and film, such as the murder mysteries written by Agatha Christie.

Microbial toxins are toxins produced by micro-organisms, including bacteria, fungi, protozoa, dinoflagellates, and viruses. Many microbial toxins promote infection and disease by directly damaging host tissues and by disabling the immune system. Endotoxins most commonly refer to the lipopolysaccharide (LPS) or lipooligosaccharide (LOS) that are in the outer plasma membrane of Gram-negative bacteria. The botulinum toxin, which is primarily produced by Clostridium botulinum and less frequently by other Clostridium species, is the most toxic substance known in the world. However, microbial toxins also have important uses in medical science and research. Currently, new methods of detecting bacterial toxins are being developed to better isolate and understand these toxins. Potential applications of toxin research include combating microbial virulence, the development of novel anticancer drugs and other medicines, and the use of toxins as tools in neurobiology and cellular biology.

Post-mortem chemistry, also called necrochemistry or death chemistry, is a subdiscipline of chemistry in which the chemical structures, reactions, processes and parameters of a dead organism is investigated. Post-mortem chemistry plays a significant role in forensic pathology. Biochemical analyses of vitreous humor, cerebrospinal fluid, blood and urine is important in determining the cause of death or in elucidating forensic cases.

<span class="mw-page-title-main">Thanatotranscriptome</span> Part of the genome still active in the time immediately following death

The thanatotranscriptome denotes all RNA transcripts produced from the portions of the genome still active or awakened in the internal organs of a body following its death. It is relevant to the study of the biochemistry, microbiology, and biophysics of thanatology, in particular within forensic science. Some genes may continue to be expressed in cells for up to 48 hours after death, producing new mRNA. Certain genes that are generally inhibited since the end of fetal development may be expressed again at this time.

The necrobiome has been defined as the community of species associated with decaying remains after the death of an organism. The process of decomposition is complex. Microbes decompose cadavers, but other organisms including fungi, nematodes, insects, and larger scavenger animals also contribute. Once the immune system is no longer active, microbes colonizing the intestines and lungs decompose their respective tissues and then travel throughout the body via the circulatory and lymphatic systems to break down other tissue and bone. During this process, gases are released as a by-product and accumulate, causing bloating. Eventually, the gases seep through the body's wounds and natural openings, providing a way for some microbes to exit from the inside of the cadaver and inhabit the outside. The microbial communities colonizing the internal organs of a cadaver are referred to as the thanatomicrobiome. The region outside of the cadaver that is exposed to the external environment is referred to as the epinecrotic microbial communities of the necrobiome, and is especially important when determining the time and location of death for an individual. Different microbes play specific roles during each stage of the decomposition process. The microbes that colonize the cadaver and the rate of their activity are determined by the cadaver itself and the cadaver's surrounding environmental conditions.

<span class="mw-page-title-main">Corpse decomposition</span> Process in which animal bodies break down

Decomposition is the process in which the organs and complex molecules of animal and human bodies break down into simple organic matter over time. In vertebrates, five stages of decomposition are typically recognized: fresh, bloat, active decay, advanced decay, and dry/skeletonized. Knowing the different stages of decomposition can help investigators in determining the post-mortem interval (PMI). The rate of decomposition of human remains can vary due to environmental factors and other factors. Environmental factors include temperature, burning, humidity, and the availability of oxygen. Other factors include body size, clothing, and the cause of death.

<span class="mw-page-title-main">Walter Stanley Haines</span> American forensic scientist and teacher

Walter Stanley Haines was an American professor of chemistry, materia medica, and toxicology. He taught at Rush Medical College in Chicago for almost 50 years, and was acclaimed for his teaching. With Frederick Peterson, he published a comprehensive guide to medicine and the law, A Textbook on Legal Medicine and Toxicology, which went through many editions.

The stages of death of a human being have medical, biochemical and legal aspects. The term taphonomy from palaeontology applies to the fate of all kinds of remains of organisms. Forensic taphonomy is concerned with remains of the human body.

References

  1. "Post-Mortem Caloricity of Yellow Fever". The Boston Medical and Surgical Journal. 33 (1): 14–17. 1845-08-06. doi:10.1056/nejm184508060330104. ISSN   0096-6762.

Sources