Pharmacology is the science of medical drugs and medications, including a substance's origin, composition, pharmacokinetics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals.
Actaea racemosa, the black cohosh, black bugbane, black snakeroot, rattle-top, or fairy candle, is a species of flowering plant of the family Ranunculaceae. It is native to eastern North America from the extreme south of Ontario to central Georgia, and west to Missouri and Arkansas. It grows in a variety of woodland habitats, and is often found in small woodland openings. The roots and rhizomes are used in traditional medicine by Native Americans. Its extracts are manufactured as herbal medicines or dietary supplements. Most dietary supplements containing black cohosh are not well-studied or recommended for safe and effective use in treating menopause symptoms or any disease. In contrast, some herbal medicinal products containing black cohosh extract hold a marketing authorization in several states of the European Union and are well-studied and recommended for safe and effective use for the relief of menopausal symptoms such as hot flushes and profuse sweating attacks. Such differentiation between the product types seems to be important.
Herbal medicine is the study of pharmacognosy and the use of medicinal plants, which are a basis of traditional medicine. With worldwide research into pharmacology, some herbal medicines have been translated into modern remedies, such as the anti-malarial group of drugs called artemisinin isolated from Artemisia annua, a herb that was known in Chinese medicine to treat fever. There is limited scientific evidence for the safety and efficacy of many plants used in 21st-century herbalism, which generally does not provide standards for purity or dosage. The scope of herbal medicine sometimes include fungal and bee products, as well as minerals, shells and certain animal parts.
Medicinal plants, also called medicinal herbs, have been discovered and used in traditional medicine practices since prehistoric times. Plants synthesize hundreds of chemical compounds for various functions, including defense and protection against insects, fungi, diseases, and herbivorous mammals.
The regulation of therapeutic goods, defined as drugs and therapeutic devices, varies by jurisdiction. In some countries, such as the United States, they are regulated at the national level by a single agency. In other jurisdictions they are regulated at the state level, or at both state and national levels by various bodies, as in Australia.
Pharmacovigilance, also known as drug safety, is the pharmaceutical science relating to the "collection, detection, assessment, monitoring, and prevention" of adverse effects with pharmaceutical products. The etymological roots for the word "pharmacovigilance" are: pharmakon and vigilare. As such, pharmacovigilance heavily focuses on adverse drug reactions (ADR), which are defined as any response to a drug which is noxious and unintended, including lack of efficacy. Medication errors such as overdose, and misuse and abuse of a drug as well as drug exposure during pregnancy and breastfeeding, are also of interest, even without an adverse event, because they may result in an adverse drug reaction.
The European Medicines Agency (EMA) is an agency of the European Union (EU) in charge of the evaluation and supervision of pharmaceutical products. Prior to 2004, it was known as the European Agency for the Evaluation of Medicinal Products or European Medicines Evaluation Agency (EMEA).
Ethnomedicine is a study or comparison of the traditional medicine based on bioactive compounds in plants and animals and practiced by various ethnic groups, especially those with little access to western medicines, e.g., indigenous peoples. The word ethnomedicine is sometimes used as a synonym for traditional medicine.
Ethnoveterinary medicine (EVM) considers that traditional practices of veterinary medicine are legitimate and seeks to validate them. Many non-Western traditions of veterinary medicine exist, such as acupuncture and herbal medicine in China, Tibetan veterinary medicine, Ayurveda in India, etc. These traditions have written records that go back thousands of years, for example the Jewish sources in the Old Testament and Talmud and the Sri Lankan 400-year-old palm-leaf frond records of veterinary treatments. Since colonial times scientists had always taken note of indigenous knowledge of animal health and diagnostic skills before implementing their Western-technology projects.
The European Directorate for the Quality of Medicines & HealthCare (EDQM) is a Directorate of the Council of Europe that traces its origins and statutes to the Convention on the Elaboration of a European Pharmacopoeia.
Pharmacy in China involves the activities engaged in the preparation, standardization and dispensing of drugs, and its scope includes the cultivation of plants that are used as drugs, the synthesis of chemical compounds of medicinal value, and the analysis of medicinal agents. Pharmacists in China are responsible for the preparation of the dosage forms of drugs, such as tablets, capsules, and sterile solutions for injection. They compound physicians', dentists', and veterinarians' prescriptions for drugs. Pharmacological activities are also closely related to pharmacy in China.
Baidyanath Group is an Ayurvedic pharmaceutical company in India.
Rotheca myricoides is a species of flowering plant in the family Lamiaceae. It is native to Africa and widely cultivated elsewhere. In cultivation, it is frequently known by one of its synonyms, such as Clerodendrum myricoides.
Traditional African medicine is a range of traditional medicine disciplines involving indigenous herbalism and African spirituality, typically including diviners, midwives, and herbalists. Practitioners of traditional African medicine claim, largely without evidence, to be able to cure a variety of diverse conditions including cancer, psychiatric disorders, high blood pressure, cholera, most venereal diseases, epilepsy, asthma, eczema, fever, anxiety, depression, benign prostatic hyperplasia, urinary tract infections, gout, and healing of wounds and burns and Ebola.
Quercus infectoria or the Aleppo oak is a species of oak well known for producing galls that have been traditionally used for centuries in Asia medicinally while also used in softening leather and in making black dye and ink.
BGR-34 is an Ayurvedic-derived product that is sold in India as an over-the-counter pill for the management of type 2 diabetes. It was developed in 2015 by two government-owned laboratories and launched commercially in 2016. It has been tested in only one, modest-sized, human trial. The drug has been heavily criticized, and without more clinical trials, its efficacy remains unproven. The manufacturers have refused to acknowledge the claims of inefficacy and other concerns.
The European Scientific Cooperative on Phytotherapy (ESCOP) was founded in 1989 as an umbrella organisation, representing national European phytotherapy associations. Associations in non-EU states can also be members of ESCOP.
The medical ethnobotany of India is the study of Indian medicinal plants and their traditional uses. Plants have been used in the Indian subcontinent for treatment of disease and health maintenance for thousands of years, and remain important staples of health and folk medicine for millions. Indians today utilize plants for both primary medical care and as supplementary treatment alongside modern medical science. It is estimated that 70% of rural Indians use traditional plant based remedies for primary healthcare needs. This reliance of plants for medicine is consistent with trends widely observed in the developing world, where between 65% and 80% of people use medicinal plant remedies.
T. Parimelazhagan is currently working as a Professor and Head of the Department of Botany, Bharathiar University, Tamil Nadu. He is known for his expertise in phytomedicine and bioprospecting of medicinal plants. He has committed his research to analyse and isolating various phytocompounds and evaluating the valuable properties of traditional medicinal plants.
