RAB40A

RAB40A
Identifiers
Aliases	RAB40A , RAR2, RAR2A, member RAS oncogene family
External IDs	HomoloGene: 89095; GeneCards: RAB40A; OMA:RAB40A - orthologs
Gene location (Human) Chr. X chromosome (human) [1] Band Xq22.2 Start 103,499,130 bp [1] End 103,519,489 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle corpus epididymis right ovary left ovary stromal cell of endometrium body of uterus left uterine tube tail of epididymis gastric mucosa canal of the cervix n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GTP binding GTPase activity Cellular component membrane endosome plasma membrane synaptic vesicle secretory granule membrane Golgi membrane Biological process intracellular signal transduction protein ubiquitination vesicle docking involved in exocytosis protein secretion protein localization to plasma membrane regulation of exocytosis intracellular protein transport Rab protein signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 142684 n/a Ensembl ENSG00000172476 n/a UniProt Q8WXH6 n/a RefSeq (mRNA) NM_080879 n/a RefSeq (protein) NP_543155 n/a Location (UCSC) Chr X: 103.5 – 103.52 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Ras-related protein Rab-40A is a protein that in humans is encoded by the RAB40A gene. ^{[3] [4]}

References

1. GRCh38: Ensembl release 89: ENSG00000172476 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Pereira-Leal JB, Seabra MC (Nov 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): 889–901. doi:10.1006/jmbi.2001.5072. PMID   11697911.
4. "Entrez Gene: RAB40A RAB40A, member RAS oncogene family".

Further reading

• Kile BT, Schulman BA, Alexander WS, et al. (2002). "The SOCS box: a tale of destruction and degradation". Trends Biochem. Sci. 27 (5): 235–41. doi:10.1016/S0968-0004(02)02085-6. PMID   12076535.
• Kuroda TS, Fukuda M, Ariga H, Mikoshiba K (2002). "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain". J. Biol. Chem. 277 (11): 9212–8. doi: 10.1074/jbc.M112414200 . PMID   11773082.
• Fukuda M, Kuroda TS, Mikoshiba K (2002). "Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport". J. Biol. Chem. 277 (14): 12432–6. doi: 10.1074/jbc.C200005200 . PMID   11856727.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. 278 (17): 15373–80. doi: 10.1074/jbc.M212341200 . PMID   12578829.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC   2665286 . PMID   15772651.
• Itoh T, Satoh M, Kanno E, Fukuda M (2006). "Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity". Genes Cells. 11 (9): 1023–37. doi:10.1111/j.1365-2443.2006.00997.x. PMID   16923123. S2CID   43042490.