RHOXF2

RHOXF2
Identifiers
Aliases	RHOXF2 , CT107, PEPP-2, PEPP2, THG1, Rhox homeobox family member 2
External IDs	OMIM: 300447; HomoloGene: 129688; GeneCards: RHOXF2; OMA:RHOXF2 - orthologs
Gene location (Human) Chr. X chromosome (human) [1] Band Xq24 Start 120,158,613 bp [1] End 120,165,630 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad right testis left testis right uterine tube blood primary visual cortex human kidney human musculoskeletal system intestine n/a More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding sequence-specific DNA binding DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding Cellular component nucleus Biological process regulation of transcription, DNA-templated positive regulation of gene expression regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84528 n/a Ensembl ENSG00000131721 n/a UniProt Q9BQY4 n/a RefSeq (mRNA) NM_032498 n/a RefSeq (protein) NP_115887 n/a Location (UCSC) Chr X: 120.16 – 120.17 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Rhox homeobox family, member 2 also known as paired-like homeobox protein (PEPP-2) is a protein in humans that is encoded by the RHOXF2 gene. ^[3]

RHOXF2 contains a glutamine-rich N-terminus, a homeodomain, and a proline-rich C-terminus. ^[4]

References

1. GRCh38: Ensembl release 89: ENSG00000131721 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: Rhox homeobox family, member 2".
4. Wayne CM, MacLean JA, Cornwall G, Wilkinson MF (November 2002). "Two novel human X-linked homeobox genes, hPEPP1 and hPEPP2, selectively expressed in the testis". Gene. 301 (1–2): 1–11. doi:10.1016/S0378-1119(02)01087-9. PMID   12490318.