RNASE6

Last updated
RNASE6
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases RNASE6 , RAD1, RNS6, RNasek6, ribonuclease A family member k6
External IDs MGI: 1925666 HomoloGene: 4102 GeneCards: RNASE6
Gene location (Human)
Ideogram human chromosome 14.svg
Chr. Chromosome 14 (human) [1]
Human chromosome 14 ideogram.svg
HSR 1996 II 3.5e.svg
Red rectangle 2x18.png
Band 14q11.2Start20,781,051 bp [1]
End20,782,467 bp [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005615

NM_030098
NM_001360117

RefSeq (protein)

NP_005606
NP_005606.1

NP_084374
NP_001347046

Location (UCSC) Chr 14: 20.78 – 20.78 Mb Chr 14: 51.12 – 51.13 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ribonuclease A family member k6 is a protein that in humans is encoded by the RNASE6 gene. [5]

Protein biological molecule consisting of chains of amino acid residues

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity.

Gene Basic physical and functional unit of heredity

In biology, a gene is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic trait. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that constitute life.

Contents

Function

The protein encoded by this gene is a member of the ribonuclease A superfamily and functions in the urinary tract. The protein has broad-spectrum antimicrobial activity against pathogenic bacteria. [provided by RefSeq, Nov 2014].

Related Research Articles

b(0,+)-type amino acid transporter 1 protein-coding gene in the species Homo sapiens

b(0,+)-type amino acid transporter 1, also known as b(0,+)AT1, is a protein which in humans is encoded by the SLC7A9 gene.

Epigen protein-coding gene in the species Homo sapiens

Epigen also known as epithelial mitogen is a protein that in humans is encoded by the EPGN gene.

GPR45 protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 45 is a protein that in humans is encoded by the GPR45 gene.

GPRC5D protein-coding gene in the species Homo sapiens

G-protein coupled receptor family C group 5 member D is a protein that in humans is encoded by the GPRC5D gene.

RPP40 protein-coding gene in the species Homo sapiens

Ribonuclease P protein subunit p40 is an enzyme that in humans is encoded by the RPP40 gene.

OR5K1 protein-coding gene in the species Homo sapiens

Olfactory receptor 5K1 is a protein that in humans is encoded by the OR5K1 gene.

OR6K2 protein-coding gene in the species Homo sapiens

Olfactory receptor 6K2 is a protein that in humans is encoded by the OR6K2 gene.

OR6K6 protein-coding gene in the species Homo sapiens

Olfactory receptor 6K6 is a protein that in humans is encoded by the OR6K6 gene.

OR8K1 protein-coding gene in the species Homo sapiens

Olfactory receptor 8K1 is a protein that in humans is encoded by the OR8K1 gene.

DLX1 protein-coding gene in the species Homo sapiens

Homeobox protein DLX-1 is a protein that in humans is encoded by the DLX1 gene.

CAPN9 protein-coding gene in the species Homo sapiens

Calpain-9 is a protein that in humans is encoded by the CAPN9 gene.

KCNH3 protein-coding gene in the species Homo sapiens

Potassium voltage-gated channel subfamily H member 3 is a protein that in humans is encoded by the KCNH3 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

DEFA3 protein-coding gene in the species Homo sapiens

Defensin, alpha 3 (DEFA3) also known as human alpha defensin 3, human neutrophil peptide 3 (HNP-3) or neutrophil defensin 3 is a human protein that is encoded by the DEFA3 gene. Human alpha defensin 3 belongs to the alpha defensin family of antimicrobial peptides.

RPS6KA6 protein-coding gene in the species Homo sapiens

Ribosomal protein S6 kinase, 90kDa, polypeptide 6 is a protein in humans that is encoded by the RPS6KA6 gene.

CLTB protein-coding gene in the species Homo sapiens

Clathrin, light chain B is a protein in humans that is encoded by the CLTB gene.

CAMK1D protein-coding gene in the species Homo sapiens

Calcium/calmodulin-dependent protein kinase ID is a protein in humans that is encoded by the CAMK1D gene on chromosome 10.

Monocarboxylate transporter 6 protein-coding gene in the species Homo sapiens

Monocarboxylate transporter 6 (MCT6) is a protein in humans that is encoded by the SLC16A5 gene.

PAN3 protein-coding gene in the species Homo sapiens

PAN3 poly(A) specific ribonuclease subunit is a protein that in humans is encoded by the PAN3 gene.

RNASEH2C protein-coding gene in the species Homo sapiens

Ribonuclease H2 subunit C is a protein that in humans is encoded by the RNASEH2C gene. RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits, and degrades the RNA of RNA:DNA hybrids.

Ribosomal modification protein rimk like family member b protein-coding gene in the species Homo sapiens

Ribosomal modification protein rimK like family member B is a protein that in humans is encoded by the RIMKLB gene.

References

Further reading

Digital object identifier Character string used as a permanent identifier for a digital object, in a format controlled by the International DOI Foundation

In computing, a Digital Object Identifier or DOI is a persistent identifier or handle used to identify objects uniquely, standardized by the International Organization for Standardization (ISO). An implementation of the Handle System, DOIs are in wide use mainly to identify academic, professional, and government information, such as journal articles, research reports and data sets, and official publications though they also have been used to identify other types of information resources, such as commercial videos.

PubMed Central (PMC) is a free digital repository that archives publicly accessible full-text scholarly articles that have been published within the biomedical and life sciences journal literature. As one of the major research databases within the suite of resources that have been developed by the National Center for Biotechnology Information (NCBI), PubMed Central is much more than just a document repository. Submissions into PMC undergo an indexing and formatting procedure which results in enhanced metadata, medical ontology, and unique identifiers which all enrich the XML structured data for each article on deposit. Content within PMC can easily be interlinked to many other NCBI databases and accessed via Entrez search and retrieval systems, further enhancing the public's ability to freely discover, read and build upon this portfolio of biomedical knowledge.


This article incorporates text from the United States National Library of Medicine, which is in the public domain.

United States National Library of Medicine the worlds largest medical library, operated by the US federal government

The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library.

The public domain consists of all the creative works to which no exclusive intellectual property rights apply. Those rights may have expired, been forfeited, expressly waived, or may be inapplicable.