RRP1B

RRP1B
Identifiers
Aliases	RRP1B , KIAA0179, NNP1L, Nnp1, PPP1R136, RRP1, ribosomal RNA processing 1B
External IDs	OMIM: 610654; MGI: 1919712; HomoloGene: 57086; GeneCards: RRP1B; OMA:RRP1B - orthologs
Gene location (Human) Chr. Chromosome 21 (human) [1] Band 21q22.3 Start 43,659,560 bp [1] End 43,696,079 bp [1]
Gene location (Mouse) Chr. Chromosome 17 (mouse) [2] Band 17|17 B1 Start 32,255,074 bp [2] End 32,281,839 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in germinal epithelium gingival epithelium visceral pleura parietal pleura tibia retinal pigment epithelium endothelial cell tendon of biceps brachii skin of hip mucosa of paranasal sinus Top expressed in tail of embryo neural layer of retina Rostral migratory stream primitive streak genital tubercle epiblast embryo morula embryo blastocyst More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA binding transcription coactivator activity protein binding Cellular component heterochromatin preribosome, small subunit precursor cytosol euchromatin nucleolus nucleus preribosome, large subunit precursor granular component nucleoplasm chromosome Biological process negative regulation of phosphatase activity rRNA processing negative regulation of GTPase activity positive regulation of apoptotic process regulation of RNA splicing positive regulation of transcription by RNA polymerase II cellular response to virus mRNA processing apoptotic process RNA splicing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23076 72462 Ensembl ENSG00000160208 ENSMUSG00000058392 UniProt Q14684 Q91YK2 RefSeq (mRNA) NM_015056 NM_001163734 NM_028244 RefSeq (protein) NP_055871 NP_001157206 NP_082520 Location (UCSC) Chr 21: 43.66 – 43.7 Mb Chr 17: 32.26 – 32.28 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ribosomal RNA processing protein 1 homolog B is a protein encoded by RRP1B gene ^[5] which is located on Chromosome 21.

References

1. GRCh38: Ensembl release 89: ENSG00000160208 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000058392 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: KIAA0179 KIAA0179".

Further reading

• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.
• Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (October 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID   16964243. S2CID   14294292.
• Hu YH, Warnatz HJ, Vanhecke D, Wagner F, Fiebitz A, Thamm S, Kahlem P, Lehrach H, Yaspo ML, Janitz M (June 2006). "Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins". BMC Genomics. 7 155. doi: 10.1186/1471-2164-7-155 . PMC   1526728 . PMID   16780588.
• Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R (April 2006). "Phosphoproteome analysis of the human mitotic spindle". Proceedings of the National Academy of Sciences of the United States of America. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi: 10.1073/pnas.0507066103 . PMC   1459365 . PMID   16565220.
• Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (January 2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID   15635413. S2CID   4344740.
• Lehner B, Sanderson CM (July 2004). "A protein interaction framework for human mRNA degradation". Genome Research. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC   442147 . PMID   15231747.
• Scherl A, Couté Y, Déon C, Callé A, Kindbeiter K, Sanchez JC, Greco A, Hochstrasser D, Diaz JJ (November 2002). "Functional proteomic analysis of human nucleolus". Molecular Biology of the Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC   133617 . PMID   12429849.
• Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI (January 2002). "Directed proteomic analysis of the human nucleolus". Current Biology. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi: 10.1016/S0960-9822(01)00650-9 . PMID   11790298. S2CID   14132033.
• Nagase T, Seki N, Ishikawa K, Tanaka A, Nomura N (February 1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1". DNA Research. 3 (1): 17–24. doi: 10.1093/dnares/3.1.17 . PMID   8724849.