Reticulohistiocytosis | |
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Specialty | Dermatology |
Reticulohistiocytosis is a cutaneous condition of which there are two distinct forms: [1] :718–9
Reticulohistiocytoma is a cutaneous condition characterized by a solitary, firm, dermal skin lesion of less than 1 cm in diameter. It usually occurs in young adults or middle aged people, most commonly in females. Affected regions include the head and neck region and the upper part of the trunk. It may coexist with certain neoplasms or vasculitis, and in 30 percent of patients with xanthelasma.
Multicentric reticulohistiocytosis is a multisystem disease beginning usually around the age of 50 years, and is twice as common in women.
Langerhans cell histiocytosis (LCH) is a rare cancer involving clonal proliferation of Langerhans cells, abnormal cells deriving from bone marrow and capable of migrating from skin to lymph nodes. Clinically, its manifestations range from isolated bone lesions to multisystem disease. LCH is part of a group of clinical syndromes called histiocytoses, which are characterized by an abnormal proliferation of histiocytes. These diseases are related to other forms of abnormal proliferation of white blood cells, such as leukemias and lymphomas.
Crystal arthropathy is a class of joint disorder that is characterized by accumulation of tiny crystals in one or more joints. Polarizing microscopy and application of other crystallographic techniques have improved identification of different microcrystals including monosodium urate, calcium pyrophosphate dihydrate, calcium hydroxyapatite, and calcium oxalate.
Ronald P. Rapini, M.D., is an American dermatologist and dermatopathologist. He is the Josey Professor and Chair of the Department of Dermatology at the University of Texas Health Science Center at Houston and MD Anderson Cancer Center.
Non-Langerhans cell histiocytosis refers to a family of histiocytosis characterized by the absence of Langerhans cells.
Non-X histiocytoses are a clinically well-defined group of cutaneous syndromes characterized by infiltrates of monocytes/macrophages, as opposed to X-type histiocytoses in which the infiltrates contain Langerhans cells. Conditions included in this group are:
X-type histiocytoses are a clinically well-defined group of cutaneous syndromes characterized by infiltrates of Langerhans cells, as opposed to Non-X histiocytosis in which the infiltrates contain monocytes/macrophages. Conditions included in this group are:
Congenital self-healing reticulohistiocytosis is a condition that is a self-limited form of Langerhans cell histiocytosis.
Giant-cell reticulohistiocytoma is a cutaneous condition characterized by a solitary skin lesion.
Ken Hashimoto was a Japanese professor of dermatology resident in the United States, who pioneered research in skin disease using electron microscopy and histochemistry.
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