Rexford Ahima | |
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Born | Rexford Sefah Ahima |
Nationality | American-Ghanaian |
Alma mater | Accra Academy (1976; 1978) University of London (B.Sc.,1981) University of Ghana (M.D.,1986) Tulane University (Ph.D,1992) |
Scientific career | |
Fields | Medicine. |
Institutions | Johns Hopkins University University of Pennsylvania Harvard University Albert Einstein College of Medicine |
Rexford Sefah Ahima is a professor of medicine, Public Health and Nursing; Bloomberg Distinguished Professor of Diabetes at the Johns Hopkins Medical School; and the Director of the Division of Endocrinology, Diabetes and Metabolism, Johns Hopkins University School of Medicine. [1] Ahima's research focuses on central and peripheral actions of adipocyte hormones in energy homeostasis, and glucose and lipid metabolism. [2] [3]
Rexford Ahima had his high school education at Accra Academy in Ghana. He gained a Bachelor of Science degree in Endocrinology from the Middlesex Hospital Medical School, University of London in 1981. He received his M.D. from the University of Ghana Medical School in 1986 and a Ph.D. from Tulane University in New Orleans, Louisiana in 1992. Ahima had his residency training in Internal Medicine at the Albert Einstein College of Medicine, Jack D. Weiler Hospital and Jacobi Medical Center in New York. Ahima did his clinical and research fellowship training in Endocrinology, Diabetes and Metabolism at the Beth Israel Deaconess Medical Center and Harvard Medical School in Boston.
At Harvard, he had his research fellowship in the laboratory of Dr. Jeffrey S. Flier, after which he served as an instructor in medicine at Harvard before moving to the University of Pennsylvania in 1999. He became a tenured professor of medicine at the Perelman School of Medicine at the University of Pennsylvania and was the Director of Obesity Unit, Institute for Diabetes, Obesity and Metabolism and Director of Diabetes Research Center Mouse Phenotyping Core.
In 2016, Ahima joined Johns Hopkins University as a Bloomberg Distinguished Professor of Diabetes with appointments in the School of Medicine, School of Nursing, and Bloomberg School of Public Health. He was also appointed Leader of the Johns Hopkins University Diabetes Initiative and Director of the Division of Endocrinology, Diabetes and Metabolism. [3]
Dr. Ahima's laboratory investigates CNS and peripheral actions of adipokines in energy homeostasis, and glucose and lipid metabolism. He has performed seminal studies to define the roles of leptin, adiponectin and resistin in obesity and diabetes using genetic techniques and metabolic phenotyping of mouse models. Moreover, he is involved in clinical and population studies focusing on the pathogenesis of obesity and Diabetes.
Ahima was elected to the National Academy of Medicine in 2020, [4] [5] the American Academy of Arts and Sciences in 2023, the American Society for Clinical Investigation in 2005, the Association of American Physicians in 2010), [6] the Interurban Clinical Club, and is a fellow of the American Association for the Advancement of Science, the American College of Physicians, and the Obesity Society. He is a past associate editor of the journals Gastroenterology, Molecular Endocrinology , Endocrinology , and Endocrine Reviews. He was the editor-in-chief of the Journal of Clinical Investigation. [6] [7] He is currently the editor of the Annals of the New York Academy of Sciences Year in Diabetes and Obesity. [8] [9]
Ahima has more than 55,000 citations in Google Scholar and h-index of 93 [10]
Books
Leptin also obese protein is a protein hormone predominantly made by adipocytes. Its primary role is likely to regulate long-term energy balance.
Adipose tissue is a loose connective tissue composed mostly of adipocytes. It also contains the stromal vascular fraction (SVF) of cells including preadipocytes, fibroblasts, vascular endothelial cells and a variety of immune cells such as adipose tissue macrophages. Its main role is to store energy in the form of lipids, although it also cushions and insulates the body.
Resistin also known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) is a cysteine-rich peptide hormone derived from adipose tissue that in humans is encoded by the RETN gene.
The Pennington Biomedical Research Center is a health science-focused research center in Baton Rouge, Louisiana. It is part of the Louisiana State University System and conducts clinical, basic, and population science research. It is the largest academically-based nutrition research center in the world, with the greatest number of obesity researchers on faculty. The center's over 500 employees occupy several buildings on the 222-acre (0.90 km2) campus. The center was designed by the Baton Rouge architect John Desmond.
Adipose tissue is an endocrine organ that secretes numerous protein hormones, including leptin, adiponectin, and resistin. These hormones generally influence energy metabolism, which is of great interest to the understanding and treatment of type 2 diabetes and obesity.
Daniel Willett Foster was the John Denis McGarry, Ph.D. Distinguished Chair in Diabetes and Metabolic Research and Professor of Internal Medicine at the University of Texas Southwestern Medical School at Dallas. He was Chairman of the Department of Internal Medicine for 16 years. He was a Fellow of the American Academy of Arts and Sciences, a Fellow of the American Association for the Advancement of Science and a member of the Institute of Medicine of the National Academies. He was a Master of the American College of Physicians. He was also a former member of the President's Council on Bioethics.
Michael Cowley FTSE is an Australian physiologist. He is best known for his mapping of the neural circuits involved in metabolism and obesity and diabetes treatment. He is a professor in the Department of Physiology at Monash University in the Faculty of Biomedical and Psychological Sciences. He is also a director of the Australian diabetes drug development company, Verva Inc, and director of the Monash Obesity & Diabetes Institute] (modi).
JeffreyFlier is an American physician, endocrinologist; widely cited scientist; the Higginson Professor of Medicine and Physiology at Harvard Medical School; and a Distinguished Service Professor at the same institution. He was the 21st Dean of the Faculty of Medicine at Harvard University from 2007 to 2016.
Bernhard Ludvik is a Specialist in Internal Medicine, board certified in Endocrinology and Metabolism. He is currently an Associate Professor of Medicine at the Medical University of Vienna. He serves as the Deputy Head of the Division of Endocrinology and Metabolism at the General Hospital Vienna.
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José F. Caro is an American physician, scientist, and educator most notable for his research in obesity and diabetes. The Institute for Scientific Information listed him the third most cited investigator in the world in the field of obesity research during the 1991-2000 period for his work on Leptin. Caro is an artist and a signature member of the Pastel Society of America.
Matthias H. Tschöp is a German physician and scientist. He is the chief executive officer and scientific director of Helmholtz Zentrum München, German Research Center for Environmental Health. He is also Alexander von Humboldt Professor and chair of metabolic diseases at Technical University of Munich and serves as an adjunct professor at Yale University.
Christos Socrates Mantzoros is a Greek American physician-scientist, practicing internist-endocrinologist, teacher and researcher. He is a professor of medicine at Harvard Medical School and an adjunct professor at Boston University School of Medicine. He currently serves as the chief of endocrinology, diabetes and metabolism at the VA Boston Healthcare System, where he created de novo a leading academic division true to its tripartite mission and as the founding director of human nutrition at Beth Israel Deaconess Medical Center (BIDMC), Harvard Medical School. Finally, he holds the editor-in-chief position of the journal Metabolism: Clinical and Experimental.
Malcolm Daniel Lane was a biochemist who spent most of his career on the faculty at the Johns Hopkins School of Medicine in Baltimore, Maryland. Lane served as the head of the Department of Biological Chemistry from 1978 to 1997, was elected to the National Academy of Sciences in 1987, and was named a University Distinguished Service Professor – the institution's highest academic title – in 2001. Lane's research focused on the biochemistry of lipids and lipid metabolism, and the resulting physiological mechanisms regulating adipogenesis and obesity.
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Eleftheria Maratos-Flier is an American endocrinologist, and emerita Professor of Medicine at Harvard Medical School, best known for her expertise in the pathophysiology and prevention of obesity-related metabolic disorders, and for her discoveries on the neuroendocrine control of feeding behaviour. She is a contributing author to known textbooks and reviews in internal medicine, endocrinology, and physiology. Her marriage with professor Jeffrey Flier, was noted by Forbes as a lasting and productive bond between eminent medical scholars. They have two adult daughters who are also physicians. She is also known as Terry Maratos-Flier.