After beginning the 2022 season with the Triple-AColumbus Clippers,Palacios was recalled by the Guardians on April 25,2022,and made his major league debut that same day,starting in left field. He collected his first career hit in the same game,a single off of Los Angeles Angels starter Michael Lorenzen.[10] He played in 54 games during his rookie campaign,hitting .232/.293/.286 with no home runs and 10 RBI.
Palacios was optioned to Triple-A Columbus to begin the 2023 season.[11] In 56 games with Columbus,Palacios batted .217/.351/.318 with 3 home runs,30 RBI,and 6 stolen bases. On June 11,2023,Palacios was designated for assignment by the Guardians after Cody Morris was returned from the injured list.[12]
St. Louis Cardinals
On June 16,2023,Palacios was traded to the St. Louis Cardinals in exchange for cash considerations.[13] In 32 games for the Cardinals,he batted .258/.307/.516 with 6 home runs and 16 RBI.
Tampa Bay Rays
On January 5,2024,the Cardinals traded Palacios to the Tampa Bay Rays for pitcher Andrew Kittredge.[14] In August,Palacios went on the injured list after injuring his knee while sliding headfirst into second base.[15] In his first season with the Rays,he played in a career-high 92 MLB games,batting .223 with 5 home runs and 19 stolen bases.[16] After starting the 2025 season on the injured list with a fractured right ring finger,he played in one Rays game,going 3-for-4,before returning to the injured list with another knee sprain.[17][18]
Palacios's brother,Joshua Palacios,also plays professional baseball and is in the Chicago White Sox organization. Their uncle,Rey Palacios,played in MLB from 1988 to 1990.[24][25][26] Their father,Richard also played baseball,reaching Triple-A.[27][28] Palacios' father is of Puerto Rican descent,[19] and his mother is from Curaçao.[20]
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