SANA (drug)

SANA (drug)

Identifiers
IUPAC name 2-hydroxy-5-(2-nitroethenyl)benzoic acid
CAS Number	42571-07-3
PubChem CID	54133300
Chemical and physical data
Formula	C9H7NO5
Molar mass	209.157 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1=CC(=C(C=C1C=C[N+](=O)[O-])C(=O)O)O
InChI InChI=1S/C9H7NO5/c11-8-2-1-6(3-4-10(14)15)5-7(8)9(12)13/h1-5,11H,(H,12,13) Key:NVWQBWPWSNPTBM-UHFFFAOYSA-N

SANA (MVD1) is an experimental drug with thermogenic effects which has been researched as a potential weight loss medication. ^{[1] [2] [3]}

References

1. "Eolo Pharma Publishes First-in-Human Study in Nature Metabolism on Novel Obesity Drug Activating Energy-Burning Pathway". eolo-pharma.com.
2. "In search of an obesity drug: the story of the latin american company Eolo Pharma". CITES - Centro de Innovación Tecnológica, Empresarial y Social. 14 August 2024.
3. Cal K, Leyva A, Rodríguez-Duarte J, Ruiz S, Santos L, Garat MP, et al. (2025). "A nitroalkene derivative of salicylate, SANA, induces creatine-dependent thermogenesis and promotes weight loss". Nature Metabolism. 7 (8): 1550–1569. doi: 10.1038/s42255-025-01311-z . PMC   12373507 . PMID   40527924.