STK36

STK36
Identifiers
Aliases	STK36 , FU, serine/threonine kinase 36, CILD46
External IDs	OMIM: 607652 MGI: 1920831 HomoloGene: 49432 GeneCards: STK36
Gene location (Human) Chr. Chromosome 2 (human) [1] Band 2q35 Start 218,672,069 bp [1] End 218,702,716 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 C4 Start 74,640,604 bp [2] End 74,676,053 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube anterior pituitary right lobe of thyroid gland left lobe of thyroid gland body of pancreas stromal cell of endometrium canal of the cervix left uterine tube gallbladder body of stomach Top expressed in secondary oocyte spermatid seminiferous tubule Meckel's cartilage occiput occipital bone humerus spermatocyte rib tibia More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding protein binding protein kinase activity kinase activity transferase activity transcription factor binding metal ion binding protein serine/threonine kinase activity ATP binding Cellular component nucleus cytoplasm cytosol extracellular region Biological process phosphorylation cell projection organization regulation of DNA-binding transcription factor activity multicellular organism development epithelial cilium movement involved in extracellular fluid movement brain development positive regulation of smoothened signaling pathway positive regulation of hh target transcription factor activity protein phosphorylation post-embryonic development cilium assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 27148 269209 Ensembl ENSG00000163482 ENSMUSG00000033276 UniProt Q9NRP7 Q69ZM6 RefSeq (mRNA) NM_001243313 NM_015690 NM_001369423 NM_175031 RefSeq (protein) NP_001230242 NP_056505 NP_001356352 NP_778196 NP_001391006 NP_001391007 Location (UCSC) Chr 2: 218.67 – 218.7 Mb Chr 1: 74.64 – 74.68 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Serine/threonine-protein kinase 36 is an enzyme that in humans is encoded by the STK36 gene. ^{[5] [6]}

Interactions

STK36 has been shown to interact with GLI1. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000163482 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000033276 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Murone M, Luoh SM, Stone D, Li W, Gurney A, Armanini M, Grey C, Rosenthal A, de Sauvage FJ (Aug 2000). "Gli regulation by the opposing activities of fused and suppressor of fused". Nat Cell Biol. 2 (5): 310–2. doi:10.1038/35010610. PMID   10806483. S2CID   31424234.
6. "Entrez Gene: STK36 serine/threonine kinase 36, fused homolog (Drosophila)".

Further reading

• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC   1847948 . PMID   17353931.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Østerlund T, Everman DB, Betz RC, et al. (2005). "The FU gene and its possible protein isoforms". BMC Genomics. 5 (1): 49. doi:10.1186/1471-2164-5-49. PMC   512281 . PMID   15268766.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Nakayama M, Kikuno R, Ohara O (2003). "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs". Genome Res. 12 (11): 1773–84. doi:10.1101/gr.406902. PMC   187542 . PMID   12421765.
• Nagase T, Ishikawa K, Kikuno R, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (5): 337–45. doi: 10.1093/dnares/6.5.337 . PMID   10574462.
• Gold MO, Yang X, Herrmann CH, Rice AP (1998). "PITALRE, the catalytic subunit of TAK, is required for human immunodeficiency virus Tat transactivation in vivo". J. Virol. 72 (5): 4448–53. doi:10.1128/JVI.72.5.4448-4453.1998. PMC   109679 . PMID   9557739.