Gertrude Mary Cox was an American statistician and founder of the department of Experimental Statistics at North Carolina State University. She was later appointed director of both the Institute of Statistics of the Consolidated University of North Carolina and the Statistics Research Division of North Carolina State University. Her most important and influential research dealt with experimental design; In 1950 she published the book Experimental Designs, on the subject with W. G. Cochran, which became the major reference work on the design of experiments for statisticians for years afterwards. In 1949 Cox became the first woman elected into the International Statistical Institute and in 1956 was President of the American Statistical Association.
Bioconductor is a free, open source and open development software project for the analysis and comprehension of genomic data generated by wet lab experiments in molecular biology.
Within computational biology, an MA plot is an application of a Bland–Altman plot for visual representation of genomic data. The plot visualizes the differences between measurements taken in two samples, by transforming the data onto M and A scales, then plotting these values. Though originally applied in the context of two channel DNA microarray gene expression data, MA plots are also used to visualise high-throughput sequencing analysis.
Terence Paul "Terry" Speed, FAA FRS is an Australian statistician. A senior principal research scientist at the Walter and Eliza Hall Institute of Medical Research, he is known for his contributions to the analysis of variance and bioinformatics, and in particular to the analysis of microarray data.
Robert Clifford Gentleman is a Canadian statistician and bioinformatician who is currently the founding executive director of the Center for Computational Biomedicine at Harvard Medical School. He was previously the vice president of computational biology at 23andMe. Gentleman is recognized, along with Ross Ihaka, as one of the originators of the R programming language and the Bioconductor project.
Bin Yu is a Chinese-American statistician. She is currently Chancellor's Professor in the Departments of Statistics and of Electrical Engineering & Computer Sciences at the University of California, Berkeley.
David Sankoff is a Canadian mathematician, bioinformatician, computer scientist and linguist. He holds the Canada Research Chair in Mathematical Genomics in the Mathematics and Statistics Department at the University of Ottawa, and is cross-appointed to the Biology Department and the School of Information Technology and Engineering. He was founding editor of the scientific journal Language Variation and Change (Cambridge) and serves on the editorial boards of a number of bioinformatics, computational biology and linguistics journals. Sankoff is best known for his pioneering contributions in computational linguistics and computational genomics. He is considered to be one of the founders of bioinformatics. In particular, he had a key role in introducing dynamic programming for sequence alignment and other problems in computational biology. In Pavel Pevzner's words, "[ Michael Waterman ] and David Sankoff are responsible for transforming bioinformatics from a ‘stamp collection' of ill-defined problems into a rigorous discipline with important biological applications."
Mark Johannes van der Laan is the Jiann-Ping Hsu/Karl E. Peace Professor of Biostatistics and Statistics at the University of California, Berkeley. He has made contributions to survival analysis, semiparametric statistics, multiple testing, and causal inference. He also developed the targeted maximum likelihood estimation methodology. He is a founding editor of the Journal of Causal Inference.
Bonnie Anne Berger is an American mathematician and computer scientist, who works as the Simons professor of mathematics and professor of electrical engineering and computer science at the Massachusetts Institute of Technology. Her research interests are in algorithms, bioinformatics and computational molecular biology.
Lior Samuel Pachter is a computational biologist. He works at the California Institute of Technology, where he is the Bren Professor of Computational Biology. He has widely varied research interests including genomics, combinatorics, computational geometry, machine learning, scientific computing, and statistics.
Daniel Mier Gusfield is an American computer scientist, Distinguished Professor of Computer Science at the University of California, Davis. Gusfield is known for his research in combinatorial optimization and computational biology.
Rafael Irizarry is a professor of biostatistics at the Harvard T.H. Chan School of Public Health and professor of biostatistics and computational biology at the Dana–Farber Cancer Institute. Irizarry is known as one of the founders of the Bioconductor project.
Kathryn M. Roeder is an American statistician known for her development of statistical methods to uncover the genetic basis of complex disease and her contributions to mixture models, semiparametric inference, and multiple testing. Roeder holds positions as professor of statistics and professor of computational biology at Carnegie Mellon University, where she leads a project focused on discovering genes associated with autism.
Jean Yee Hwa Yang is an Australian statistician known for her work on variance reduction for microarrays, and for inferring proteins from mass spectrometry data. Yang is a Professor in the School of Mathematics and Statistics at the University of Sydney.
Mona Singh is a Professor of Computer Science in the Lewis-Sigler Institute for Integrative Genomics at Princeton University.
Peter Lukas Bühlmann is a Swiss mathematician and statistician.
Katherine Snowden Pollard is the Director of the Gladstone Institute of Data Science and Biotechnology and a professor at the University of California, San Francisco (UCSF). She is a Chan Zuckerberg Biohub Investigator. She was awarded Fellowship of the International Society for Computational Biology in 2020 and the American Institute for Medical and Biological Engineering in 2021 for outstanding contributions to computational biology and bioinformatics.
Haiyan Huang is a Chinese-American biostatistician. She works as a professor of statistics at the University of California, Berkeley, where she directs the Center for Computational Biology. She is the coauthor of highly cited work on the human genome, published as part of the ENCODE research consortium, and has also published foundational work on the statistical modeling of experimental reproducibility.
Sündüz Keleş is a Turkish statistician specializing in statistical methods in genomics. She is a professor of statistics and of biostatistics and medical informatics at the University of Wisconsin–Madison. Her research has included the development of the FreeHi-C system for generating synthetic Hi-C data.
Barbara Elizabeth Engelhardt is an American computer scientist and specialist in bioinformatics. Working as a Professor at Stanford University, her work has focused on latent variable models, exploratory data analysis for genomic data, and QTLs. In 2021, she was awarded the Overton Prize by the International Society for Computational Biology.
