Scarabiasis

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Scarabiasis
Other namesCanthariasis or "beetle-disease"
Scarab-beetle-9239327.jpg
Top view image of a scarab beetle
Specialty Infectious disease
Symptoms Loss of appetite, diarrhea, abdominal cramps, vomiting, nausea, and insects in stool.
PreventionAvoidance of unsanitary foods and use of clothing when defecating or indulging in outdoor activities.
TreatmentMetronidazole and saline purgatives

Scarabiasis, or "beetle-disease", is a condition where beetles temporarily infest the digestive tract of other animals. It can also affect humans, and despite being a rare phenomenon, [1] it is the second most important insectal disease in humans after myiasis, which is caused by the larva of flies. The term is commonly used as a synonym of canthariasis, but the latter refers to the infection of animal tissues by beetle larva, whereas the Scarabiasis refers to the infection by adult beetles. Moreover, Scarabiasis refers to the passing of live beetles in animal faeces. [2] Reported symptoms of scarabiasis include loss of appetite, diarrhea, abdominal cramps, vomiting, nausea, and insects in stool. Scarabiasis has been known to infect the gastrointestinal tract, urogenital system, nasal sinuses, ears, and faces of mammals and other animals. [3]

Contents

Agents

Coleoptera constitutes the second most represented insect order in the infections of human organisms, only after Diptera. One of the known agents which can potentially infect humans is the beetle Tenebrio molitor, commonly known as “mealworm”, of the family Tenebrionidae. The life cycle of this organism comprises four stages including egg, larva, pupa and adult forms. The entire life cycle lasts approximately one year. Adult and the larvae feed on grains (hence the name mealworm), meat or decomposing animals including birds, spiders, rodents, lizards and some other beetles. They usually originate from damp, dark places, often in decaying cereals. Larvae of T. molitor are widely available as pet food for birds, fish, and reptiles, and they are growing their importance as food for humans, due to the fact that they are rich in proteins and they are traditionally consumed as food in many Asian countries. The insect is native to Europe, but it is now distributed worldwide. Despite being relatively popular, little is known about the mammalian parasitism of T. molitor. The worm is not obligate parasite of animals. The cigarette beetle, Lasioderma serricorne, is also reported to be an agent of Scarabiasis in humans. In 2016, the Department of Parasitology of the Sun Yat-sen University in Ghuanzhou, China, reported the first case of an eight-year-old baby girl infected by this beetle.

Infection

Given the limited number of records of scarabiasis occurrence in animals, the most frequent portal of entry of the agent in the host organism is still partially unknown. Some reported cases of scarabiasis in humans from the early 20th century were collected in rural India by Strickland and Roy, [4] professors of medical entomology at the School of Tropical Sciences in Calcutta. The authors hypothised two possible forms of entry in human organism, both equally probable. The first is the oral ingestion (per os) accidentally with food, when, for instance, young children eat food picked up from dirt or mud floors. The second one is through the anus (per anum). For example, as scarabiasis is more common in children, the time of entrance is possibly when children play outside naked, while they are sleeping, or while they are defecating. The authors speculated that the dung beetles could be attracted to the scent of human feces and crawl into the anus during defecation, but this theory was never confirmed. The more recent evidences described the oral ingestion as the most common way how the parasite entered the host. Infected humans usually host those organisms in the gastro-intestine tract, probably after ingesting it accidentally with contaminated or dirt food. Beetle larvae have been recovered, more rarely, from other human organs, such as tonsils, nose and urinary bladder, or the umbilical cord. Children are, in general. more susceptible hosts given their underdeveloped immune system. Moreover, canthariasis has been reported in a case with HIV/AIDS patients associated with skin ulcer. Ulcers in HIV patients and other diseases related to skin damages could increase susceptibility to a wide range of infections such as canthariasis. The beetles (or their larvae) which may cause canthariasis, can be intermediate hosts of other pathogens. For instance, Tenebrio molitor can be the intermediate hosts of the rat tapeworm, Hymenolepis diminuta. Only anecdotal infections by this organism were recorded in humans, and the large majority of the infected individuals were asymptomatic. However, abdominal pain, irritability, itching, and eosinophilia are among the existing symptoms in a few of the reported cases.

Diagnosis and Cure

Clinical manifestations of canthariasis vary greatly depending on the entry site of the invasion, the insect species, the number of larvae and their target tissue. It should be remembered that canthariasis may, at least initially, not give clear clinical symptoms. Infections may lead to severe damage to infant and older patient upon involvement of important organs of the body. The patients once diagnosed having canthariasis or scarabiasis should be treated in time. Dermatologic symptoms include boils, pruritus, erythema, and severe pain caused by the movement of larvae in the skin and in subcutaneous tissues. During the invasion, a polymorphic inflammatory infiltrate may be observed in neighboring tissues. The most frequently reported complication in this disease is a secondary bacterial infection. Gastric canthariasis, caused by swallowed eggs or larvae, manifests as nausea and vomiting, stomachache and abdominal bloating, loss of appetite and weight loss, or diarrhea resembling intestinal parasite infection. In extreme cases, the larvae penetrate through the wall of the digestive tract and invade other organs; this, however, is rare, because most die before reaching the small intestines. Untreated canthariasis may lead to death of the animal as a result of anaphylactic shock, intoxication or secondary bacterial infection of damaged host tissues. Fatalities among humans are not reported in the scientific literature. However, mortality in other mammals due to canthariasis infection was confirmed, for example, in weaned pigs in large-scale farming. A canthariasis case reported in Iran on a 10-year-old boy who was hit by an urogenital infection was a rare occurrence in which the beetle was hosted in the urinary system. Symptoms were intermittent, and urine contained brown sediments similar to bladder stones. Debris, hyperemia and inflammation were identified in bladder and in the urethra cystoscopy. However, no larva was seen in bladder and urethra. The patient recovered after oral Ivermectin therapy. The clinical symptoms of the only known infection by Lasioderma serricorne in the human gastrointestinal tract were relatively light.

Related Research Articles

Toxocariasis is an illness of humans caused by larvae of either the dog roundworm, the cat roundworm or the fox roundworm. Toxocariasis is often called visceral larva migrans (VLM). Depending on geographic location, degree of eosinophilia, eye and/or pulmonary signs, the terms ocular larva migrans (OLM), Weingarten's disease, Frimodt-Møller's syndrome, and eosinophilic pseudoleukemia are applied to toxocariasis. Other terms sometimes or rarely used include nematode ophthalmitis, toxocaral disease, toxocarose, and covert toxocariasis. This zoonotic, helminthic infection is a rare cause of blindness and may provoke rheumatic, neurologic, or asthmatic symptoms. Humans normally become infected by ingestion of embryonated eggs from contaminated sources.

Myiasis Infestation of parasitic maggots

Myiasis is the parasitic infestation of the body of a live animal by fly larvae (maggots) which grow inside the host while feeding on its tissue. Although flies are most commonly attracted to open wounds and urine- or feces-soaked fur, some species can create an infestation even on unbroken skin and have been known to use moist soil and non-myiatic flies as vector agents for their parasitic larvae.

Hymenolepiasis is infestation by one of two species of tapeworm: Hymenolepis nana or H. diminuta. Alternative names are dwarf tapeworm infection and rat tapeworm infection. The disease is a type of helminthiasis which is classified as a neglected tropical disease.

<i>Echinococcus multilocularis</i> Species of flatworm

Echinococcus multilocularis is a small cyclophyllid tapeworm found extensively in the northern hemisphere. E. multilocularis, along with other members of the Echinococcus genus, produce diseases known as echinococcosis. Unlike E. granulosus,E. multilocularis produces many small cysts that spread throughout the internal organs of the infected animal. The resultant disease is called Alveolar echinococcosis, and is caused by ingesting the eggs of E. multilocularis.

<i>Hymenolepis diminuta</i> Species of flatworm

Hymenolepis diminuta, also known as rat tapeworm, is a species of Hymenolepis tapeworm that causes hymenolepiasis. It has slightly bigger eggs and proglottids than H. nana and infects mammals using insects as intermediate hosts. The adult structure is 20 to 60 cm long and the mature proglottid is similar to that of H. nana, except it is larger.

<i>Taenia crassiceps</i> Species of Cestoda

Taenia crassiceps is a tapeworm in the family Taeniidae. It is a parasitic organism whose adult form infects the intestine of carnivores, like canids. It is related to Taenia solium, the pork tapeworm, and to Taenia saginata, the beef tapeworm. It is commonly found in the Northern Hemisphere, especially throughout Canada and the northern United States.

Eucestoda Subclass of tapeworms

Eucestoda, commonly referred to as tapeworms, are the larger of the two subclasses of flatworms in the class Cestoda. Larvae have six posterior hooks on the scolex (head), in contrast to the ten-hooked Cestodaria. All tapeworms are endoparasites of vertebrates, living in the digestive tract or related ducts. Examples are the pork tapeworm with a human definitive host, and pigs as the secondary host, and Moniezia expansa, the definitive hosts of which are ruminants.

Spirometra erinaceieuropaei is a parasitic tapeworm that infects domestic animals and humans. The medical term for this infection in humans and other animals is sparganosis. Morphologically, these worms are similar to other worms in the genus Spirometra. They have a long body consisting of three sections: the scolex, the neck, and the strobilia. They have a complex life cycle that consists of three hosts, and can live in varying environments and bodily tissues. Humans can contract this parasite in three main ways. Historically, humans are considered a paratenic host; however, the first case of an adult S. erinaceieuropaei infection in humans was reported in 2017. Spirometra tapeworms exist worldwide and infection is common in animals, but S. erinaceieuropaei infections are rare in humans. Treatment for infection typically includes surgical removal and anti-worm medication.

Sparganosis is a parasitic infection caused by the plerocercoid larvae of the genus Spirometra including S. mansoni, S. ranarum, S. mansonoides and S. erinacei. It was first described by Patrick Manson from China in 1882, and the first human case was reported by Charles Wardell Stiles from Florida in 1908. The infection is transmitted by ingestion of contaminated water, ingestion of a second intermediate host such as a frog or snake, or contact between a second intermediate host and an open wound or mucous membrane. Humans are the accidental hosts in the life cycle, while dogs, cats, and other mammals are definitive hosts. Copepods are the first intermediate hosts, and various amphibians and reptiles are second intermediate hosts.

Phycomycosis is an uncommon condition of the gastrointestinal tract and skin most commonly found in dogs and horses. The condition is caused by a variety of molds and fungi, and individual forms include pythiosis, zygomycosis, and lagenidiosis. Pythiosis is the most common type and is caused by Pythium, a type of water mould. Zygomycosis can also be caused by two types of zygomycetes, Entomophthorales and Mucorales. The latter type of zygomycosis is also referred to as mucormycosis. Lagenidiosis is caused by a Lagenidium species, which like Pythium is a water mould. Since both pythiosis and lagenidiosis are caused by organisms from the class Oomycetes, they are sometimes collectively referred to as oomycosis.

Abdominopelvic cavity

The abdominopelvic cavity is a body cavity that consists of the abdominal cavity and the pelvic cavity. It contains the stomach, liver, pancreas, spleen, gallbladder, kidneys, and most of the small and large intestines. It also contains the urinary bladder and internal reproductive organs. The abdominal pelvic cavity is a little pocket sac that lies way low in the base of the abdominal pelvis cavity. There's no membrane that separates out the abdominal cavity from the pelvic cavity so it is sometimes referred to as the abdominal pelvis or the peritoneal cavity. There are many diseases and disorders associated with the organs of the abdominopelvic cavity.

The discovery of disease-causing pathogens is an important activity in the field of medical science. Many viruses, bacteria, protozoa, fungi, helminthes and prions are identified as a confirmed or potential pathogen. In the United States, a Centers for Disease Control program, begun in 1995, identified over a hundred patients with life-threatening illnesses that were considered to be of an infectious cause, but that could not be linked to a known pathogen. The association of pathogens with disease can be a complex and controversial process, in some cases requiring decades or even centuries to achieve.

<i>Gongylonema pulchrum</i> Species of human parasite

Gongylonema pulchrum is the only parasite of the genus Gongylonema capable of infecting humans.

<i>Toxocara cati</i> Species of worm

Toxocara cati, also known as the feline roundworm, is a parasite of cats and other felids. It is one of the most common nematodes of cats, infecting both wild and domestic felids worldwide. Adult worms are localised in the gut of the host. In adult cats, the infection – which is called toxocariasis – is usually asymptomatic. However, massive infection in juvenile cats can be fatal.

Amoebiasis Human disease caused by amoeba protists

Amoebiasis, or amoebic dysentery, is an infection caused by Entamoeba histolytica. Amoebiasis can be present with no, mild, or severe symptoms. Symptoms may include lethargy, loss of weight, colonic ulcerations, abdominal pain, diarrhea, or bloody diarrhea. Complications can include inflammation and ulceration of the colon with tissue death or perforation, which may result in peritonitis. Anemia may develop due to prolonged gastric bleeding.

Baylisascaris procyonis, common name raccoon roundworm, is a roundworm nematode, found ubiquitously in raccoons, the definitive hosts. It is named after H. A. Baylis, who studied them in the 1920s–30s, and Greek askaris. Baylisascaris larvae in paratenic hosts can migrate, causing visceral larva migrans (VLM). Baylisascariasis as the zoonotic infection of humans is rare, though extremely dangerous due to the ability of the parasite's larvae to migrate into brain tissue and cause damage. Concern for human infection has been increasing over the years due to urbanization of rural areas resulting in the increase in proximity and potential human interaction with raccoons.

<i>Moniliformis moniliformis</i> Species of thorny-headed worm

Moniliformis moniliformis is a parasite of the Acanthocephala phylum in the family Moniliformidae. The adult worms are usually found in intestines of rodents or carnivores such as cats and dogs. The species can also infest humans, though this is rare.

Taenia serialis, also known as a canid tapeworm, is found within canines such as foxes and dogs. Adult T. serialis are parasites of carnivores, particularly dogs, with herbivorous lagomorph mammals such as rabbits and hares, serving as intermediate hosts. In definitive hosts, T. serialis is acquired by eating tissues from a variety of intermediate hosts. Accidental infection of humans though, can occur when eggs are ingested from food or water contaminated with dog feces and the human then becomes the T. serialis intermediate host.

<i>Anisakis simplex</i>

Anisakis simplex, known as the herring worm, is a species of nematode in the genus Anisakis. Like other nematodes, it infects and settles in the organs of marine animals, such as salmon, mackerels and squids. It is commonly found in cold marine waters, such as the Pacific Ocean and Atlantic Ocean.

Trematodiases Medical condition

Trematodiases, also known as trematode infections, are a group of diseases caused by the parasite trematodes. Symptoms can range from mild to severe depending on the species, number and location of trematodes in the infected organism. Symptoms depend on type of trematode present, and include chest and abdominal pain, high temperature, digestion issues, cough and shortness of breath, diarrhoea and change in appetite.

References

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  2. Karthikeyan G, Ganesh R, Sathiasekeran M (August 2008). "Scarabiasis". Indian Pediatrics. 45 (8): 697–699. PMID   18723917.
  3. Sun X, Wang LF, Feng Y, Xie H, Zheng XY, He A, et al. (May 2016). "A case report: A rare case of infant gastrointestinal canthariasis caused by larvae of Lasioderma serricorne (Fabricius, 1792) (Coleoptera: Anobiidae)". Infectious Diseases of Poverty. 5 (1): 34. doi:10.1186/s40249-016-0129-6. PMC   4853848 . PMID   27138301.
  4. Strickland C, Roy DN (July 1939). "Scarabiasis or the Presence of Beetles in the Intestine". The Indian Medical Gazette. 74 (7): 416–419. PMC   5151429 . PMID   29011819.