Schlieren imaging is a method to visualize density variations in transparent media. [1]
The term "schlieren imaging" is commonly used as a synonym for schlieren photography, though this article particularly treats visualization of the pressure field produced by ultrasonic transducers, generally in water or tissue-mimicking media. The method provides a two-dimensional (2D) projection image of the acoustic beam in real-time ("live video"). The unique properties of the method enable the investigation of specific features of the acoustic field (e.g. focal point in HIFU transducers), detection of acoustic beam-profile irregularities (e.g. due to defects in transducer) and on-line identification of time-dependent phenomena [2] (e.g. in phased array transducers). Some researchers[ who? ] say that schlieren imaging is equivalent to an X-ray radiograph of the acoustic field.[ citation needed ]
The optical setup of a schlieren imaging system may comprise the following main sections:[ citation needed ] Parallel beam, focusing element, stop (sharp edge) and a camera. The parallel beam may be achieved by a point-like light source (a laser focused into a pinhole is sometimes used) placed in the focal point of a collimating optical element. The collimating element may be a lens or a mirror. The optical stop may be realized by a razor placed horizontally or vertically in the focal point of the focusing element, carefully positioned to block the light spot image on its edge. The camera is positioned behind the stop and may be equipped with a suitable lens.[ citation needed ]
A parallel beam is described as a group of straight and parallel 'rays'.[ citation needed ] The rays cross through the transparent medium while potentially interacting with the contained acoustic field, and finally reach the focusing element.[ citation needed ] Note that the principle of a focusing element is directing (i.e. focusing) rays that are parallel - into a single point on the focal plane of the element. Thus, the population of rays crossing the focal plane of the focusing element can be divided into two groups: those that interacted with the acoustic field and those that didn't. The latter group is undisturbed by the acoustic field, so it remains parallel and forms a point in a well-defined position in the focal plane. The optical stop is positioned exactly at that point, so as to prevent all corresponding rays from further propagating through the system and to the camera.[ citation needed ] Thus we get rid of the portion of light that crossed the acoustic field without interaction. However, there are also rays that did interact with the acoustic field in the following manner: If a ray travels through a region of nonuniform density whose spatial gradient has a component orthogonal to the ray, that ray is deflected from its original orientation, as if it were passing through a prism. This ray is no longer parallel, so it doesn't intersect the focal point of the focusing element and is not blocked by the knife. In some circumstances the deflected ray escapes the knife-blade and reaches the camera to create a point-like image on the camera-sensor, with a position and intensity related to the inhomogeneity experienced by the ray. An image is formed in this way, exclusively by rays that interacted with the acoustic field, providing a mapping of the acoustic field.[ citation needed ]
The acousto-optic effect couples the optical refractive index of the medium with its density and pressure. Thus, spatial and temporal variations in pressure (e.g., due to ultrasound radiation) induces corresponding variations in refractive index. Optical wavelength and wavenumber in medium depend on refractive index. The phase acquired by electromagnetic wave traveling through the medium is related to the line-integral of the wavenumber along the propagation line.[ citation needed ]
For a plane-wave electromagnetic radiation traveling parallel to the Z-axis, the XY planes are iso-phase manifolds (regions of constant phase; the phase does not depend on coordinates (x,y)). However, when the wave emerges from the acoustic field, XY planes are not iso-phase manifolds anymore; the information about the accumulated pressure along each (x,y) line resides in the phase of the emerging radiation, forming a phase image (phasor) in the XY plane. The phase information is given by the Raman-Nath parameter: [3]
with - the piezooptic coefficient, the optical wavelength and the three-dimensional pressure field. [4] The schlieren technique converts the phase information into an intensity image, detectable by a camera or a screen.
The accepted gold-standard for quantitative acoustic measurement is the hydrophone. However, scanning the acoustic field with a hydrophone suffers from several limitations, giving rise to supplementary evaluation methods such as the schlieren imaging. The importance of the schlieren imaging technique is prominent in HIFU research and development. [5] Advantages of schlieren imaging include:
Diffraction is the interference or bending of waves around the corners of an obstacle or through an aperture into the region of geometrical shadow of the obstacle/aperture. The diffracting object or aperture effectively becomes a secondary source of the propagating wave. Italian scientist Francesco Maria Grimaldi coined the word diffraction and was the first to record accurate observations of the phenomenon in 1660.
A lens is a transmissive optical device that focuses or disperses a light beam by means of refraction. A simple lens consists of a single piece of transparent material, while a compound lens consists of several simple lenses (elements), usually arranged along a common axis. Lenses are made from materials such as glass or plastic and are ground, polished, or molded to the required shape. A lens can focus light to form an image, unlike a prism, which refracts light without focusing. Devices that similarly focus or disperse waves and radiation other than visible light are also called "lenses", such as microwave lenses, electron lenses, acoustic lenses, or explosive lenses.
Microscopy is the technical field of using microscopes to view objects and areas of objects that cannot be seen with the naked eye. There are three well-known branches of microscopy: optical, electron, and scanning probe microscopy, along with the emerging field of X-ray microscopy.
Schlieren photography is a process for photographing fluid flow. Invented by the German physicist August Toepler in 1864 to study supersonic motion, it is widely used in aeronautical engineering to photograph the flow of air around objects.
In optics, the Fraunhofer diffraction equation is used to model the diffraction of waves when plane waves are incident on a diffracting object, and the diffraction pattern is viewed at a sufficiently long distance from the object, and also when it is viewed at the focal plane of an imaging lens. In contrast, the diffraction pattern created near the diffracting object and is given by the Fresnel diffraction equation.
The point spread function (PSF) describes the response of a focused optical imaging system to a point source or point object. A more general term for the PSF is the system's impulse response; the PSF is the impulse response or impulse response function (IRF) of a focused optical imaging system. The PSF in many contexts can be thought of as the extended blob in an image that represents a single point object, that is considered as a spatial impulse. In functional terms, it is the spatial domain version of the optical transfer function (OTF) of an imaging system. It is a useful concept in Fourier optics, astronomical imaging, medical imaging, electron microscopy and other imaging techniques such as 3D microscopy and fluorescence microscopy.
Particle image velocimetry (PIV) is an optical method of flow visualization used in education and research. It is used to obtain instantaneous velocity measurements and related properties in fluids. The fluid is seeded with tracer particles which, for sufficiently small particles, are assumed to faithfully follow the flow dynamics. The fluid with entrained particles is illuminated so that particles are visible. The motion of the seeding particles is used to calculate speed and direction of the flow being studied.
Phase-contrast imaging is a method of imaging that has a range of different applications. It measures differences in the refractive index of different materials to differentiate between structures under analysis. In conventional light microscopy, phase contrast can be employed to distinguish between structures of similar transparency, and to examine crystals on the basis of their double refraction. This has uses in biological, medical and geological science. In X-ray tomography, the same physical principles can be used to increase image contrast by highlighting small details of differing refractive index within structures that are otherwise uniform. In transmission electron microscopy (TEM), phase contrast enables very high resolution (HR) imaging, making it possible to distinguish features a few Angstrom apart.
Photoacoustic imaging or optoacoustic imaging is a biomedical imaging modality based on the photoacoustic effect. Non-ionizing laser pulses are delivered into biological tissues and part of the energy will be absorbed and converted into heat, leading to transient thermoelastic expansion and thus wideband ultrasonic emission. The generated ultrasonic waves are detected by ultrasonic transducers and then analyzed to produce images. It is known that optical absorption is closely associated with physiological properties, such as hemoglobin concentration and oxygen saturation. As a result, the magnitude of the ultrasonic emission, which is proportional to the local energy deposition, reveals physiologically specific optical absorption contrast. 2D or 3D images of the targeted areas can then be formed.
In signal processing, apodization is the modification of the shape of a mathematical function. The function may represent an electrical signal, an optical transmission, or a mechanical structure. In optics, it is primarily used to remove Airy disks caused by diffraction around an intensity peak, improving the focus.
High-intensity focused ultrasound (HIFU), or MR-guided Focused Ultrasound Surgery is an incision-less therapeutic technique that uses non-ionizing ultrasonic waves to heat or ablate tissue. HIFU can be used to increase the flow of blood or lymph or to destroy tissue, such as tumors, via thermal and mechanical mechanisms. Given the prevalence and relatively low cost of ultrasound generation mechanisms, the premise of HIFU is that it is expected to be a non-invasive and low-cost therapy that can at least outperform care in the operating room.
Phased array ultrasonics (PA) is an advanced method of ultrasonic testing that has applications in medical imaging and industrial nondestructive testing. Common applications are to noninvasively examine the heart or to find flaws in manufactured materials such as welds. Single-element probes, known technically as monolithic probes, emit a beam in a fixed direction. To test or interrogate a large volume of material, a conventional probe must be physically scanned to sweep the beam through the area of interest. In contrast, the beam from a phased array probe can be focused and swept electronically without moving the probe. The beam is controllable because a phased array probe is made up of multiple small elements, each of which can be pulsed individually at a computer-calculated timing. The term phased refers to the timing, and the term array refers to the multiple elements. Phased array ultrasonic testing is based on principles of wave physics, which also have applications in fields such as optics and electromagnetic antennae.
Acoustic levitation is a method for suspending matter in air against gravity using acoustic radiation pressure from high intensity sound waves.
Acousto-optics is a branch of physics that studies the interactions between sound waves and light waves, especially the diffraction of laser light by ultrasound through an ultrasonic grating.
A Bessel beam is a wave whose amplitude is described by a Bessel function of the first kind. Electromagnetic, acoustic, gravitational, and matter waves can all be in the form of Bessel beams. A true Bessel beam is non-diffractive. This means that as it propagates, it does not diffract and spread out; this is in contrast to the usual behavior of light, which spreads out after being focused down to a small spot. Bessel beams are also self-healing, meaning that the beam can be partially obstructed at one point, but will re-form at a point further down the beam axis.
A laser beam profiler captures, displays, and records the spatial intensity profile of a laser beam at a particular plane transverse to the beam propagation path. Since there are many types of lasers—ultraviolet, visible, infrared, continuous wave, pulsed, high-power, low-power—there is an assortment of instrumentation for measuring laser beam profiles. No single laser beam profiler can handle every power level, pulse duration, repetition rate, wavelength, and beam size.
In physics, ray tracing is a method for calculating the path of waves or particles through a system with regions of varying propagation velocity, absorption characteristics, and reflecting surfaces. Under these circumstances, wavefronts may bend, change direction, or reflect off surfaces, complicating analysis.
Electronic speckle pattern interferometry (ESPI), also known as TV holography, is a technique that uses laser light, together with video detection, recording and processing, to visualise static and dynamic displacements of components with optically rough surfaces. The visualisation is in the form of fringes on the image, where each fringe normally represents a displacement of half a wavelength of the light used.
Thermoacoustic imaging was originally proposed by Theodore Bowen in 1981 as a strategy for studying the absorption properties of human tissue using virtually any kind of electromagnetic radiation. But Alexander Graham Bell first reported the physical principle upon which thermoacoustic imaging is based a century earlier. He observed that audible sound could be created by illuminating an intermittent beam of sunlight onto a rubber sheet. Shortly after Bowen's work was published, other researchers proposed methodology for thermoacoustic imaging using microwaves. In 1994 researchers used an infrared laser to produce the first thermoacoustic images of near-infrared optical absorption in a tissue-mimicking phantom, albeit in two dimensions (2D). In 1995 other researchers formulated a general reconstruction algorithm by which 2D thermoacoustic images could be computed from their "projections," i.e. thermoacoustic computed tomography (TCT). By 1998 researchers at Indiana University Medical Center extended TCT to 3D and employed pulsed microwaves to produce the first fully three-dimensional (3D) thermoacoustic images of biologic tissue [an excised lamb kidney ]. The following year they created the first fully 3D thermoacoustic images of cancer in the human breast, again using pulsed microwaves. Since that time, thermoacoustic imaging has gained widespread popularity in research institutions worldwide. As of 2008, three companies were developing commercial thermoacoustic imaging systems – Seno Medical, Endra, Inc. and OptoSonics, Inc.
Super-resolution photoacoustic imaging is a set of techniques used to enhance spatial resolution in photoacoustic imaging. Specifically, these techniques primarily break the optical diffraction limit of the photoacoustic imaging system. It can be achieved in a variety of mechanisms, such as blind structured illumination, multi-speckle illumination, or photo-imprint photoacoustic microscopy in Figure 1.