Sevoflurane, sold under the brand name Sevorane, among others, is a sweet-smelling, nonflammable, highly fluorinated methyl isopropyl ether used as an inhalational anaesthetic for induction and maintenance of general anesthesia. After desflurane, it is the volatile anesthetic with the fastest onset. While its offset may be faster than agents other than desflurane in a few circumstances, its offset is more often similar to that of the much older agent isoflurane. While sevoflurane is only half as soluble as isoflurane in blood, the tissue blood partition coefficients of isoflurane and sevoflurane are quite similar. For example, in the muscle group: isoflurane 2.62 vs. sevoflurane 2.57. In the fat group: isoflurane 52 vs. sevoflurane 50. As a result, the longer the case, the more similar will be the emergence times for sevoflurane and isoflurane.
Anesthesiology, anaesthesiology, or anaesthesia is the medical specialty concerned with the total perioperative care of patients before, during and after surgery. It encompasses anesthesia, intensive care medicine, critical emergency medicine, and pain medicine. A physician specialized in anesthesiology is called an anesthesiologist, anaesthesiologist, or anaesthetist, depending on the country. In some countries, the terms are synonymous, while in other countries they refer to different positions, and anesthetist is only used for non-physicians, such as nurse anesthetists.
Emery Neal Brown is an American statistician, neuroscientist, and anesthesiologist. He is the Warren M. Zapol Professor of Anesthesia at Harvard Medical School and at Massachusetts General Hospital (MGH), and a practicing anesthesiologist at MGH. At MIT he is the Edward Hood Taplin Professor of Medical Engineering and professor of computational neuroscience, the associate director of the Institute for Medical Engineering and Science, and the Director of the Harvard–MIT Program in Health Sciences and Technology.
Paul Frederick White, FANZCA is a researcher in anesthesiology, research consultant at Cedars-Sinai Medical Center at Los Angeles, retired professor and former holder of the Margaret Milam McDermott Distinguished Chair of Anesthesiology at The University of Texas Southwestern Medical Center at Dallas, and the author and editor of several journals and textbooks on the subject. With over 450 peer-reviewed publications and authorship in 9 anesthesiology textbooks, White has helped shape and revolutionize the field of ambulatory anesthesia and intravenous anesthesia.
David Spiegel is an American psychiatrist and the Wilson Professor and Associate Chair of Psychiatry at Stanford University School of Medicine, where he is known for his research into psycho-oncology; the neurobiology of therapeutic hypnosis, and the role of the mind-brain-body connection in cancer outcomes and management among other topics. He directs the Stanford Center on Stress and Health and is a recognized authority on hypnosis's clinical utility and neuroscience.
Jesse Menachem Ehrenfeld is an American physician. Ehrenfeld is President of the American Medical Association and Professor of Anesthesiology at the Medical College of Wisconsin. He is also a former Speaker of the Massachusetts Medical Society, where he was the youngest officer in the 228-year history of the organization. He is also a former Vice-President of the Massachusetts Society of Anesthesiologists. The inaugural recipient on the NIH Sexual and Gender Minority Research Award from the NIH Director, Ehrenfeld has been recognized for his contributions to advancing health equity. A 2008 recipient of the AMA Foundation Leadership Award, Ehrenfeld is a researcher in the field of biomedical informatics. Ehrenfeld's research interests include bioinformatics and the application of information technology to increase quality, reliability and patient safety. Ehrenfeld's work has led to the presentation of over 200 abstracts at national/international meetings and the publication of over 175 manuscripts in peer-reviewed journals. He serves as Editor-in-Chief of the Journal of Medical Systems, and is a fellow of the American Medical Informatics Association and the American Society of Anesthesiologists.
Neurosurgical anesthesiology, neuroanesthesiology, or neurological anesthesiology is a subspecialty of anesthesiology devoted to the total perioperative care of patients before, during, and after neurological surgeries, including surgeries of the central (CNS) and peripheral nervous systems (PNS). The field has undergone extensive development since the 1960s correlating with the ability to measure intracranial pressure (ICP), cerebral blood flow (CBF), and cerebral metabolic rate (CMR).
Clinical neuroscience is a branch of neuroscience that focuses on the scientific study of fundamental mechanisms that underlie diseases and disorders of the brain and central nervous system. It seeks to develop new ways of conceptualizing and diagnosing such disorders and ultimately of developing novel treatments.
Certified anesthesiologist assistants (CAAs) are highly trained master’s degree level non-physician anesthesia care providers. CAAs are integral members of the anesthesia care team as described by the American Society of Anesthesiologists (ASA). This designation must be disambiguated from the Certified Clinical Anesthesia Assistant (CCAA) designation conferred by the Canadian Society of Respiratory Therapists. All CAAs possess a baccalaureate degree, and complete an intensive didactic and clinical program at a postgraduate level. CAAs are trained in the delivery and maintenance of all types of anesthesia care as well as advanced patient monitoring techniques. The goal of CAA education is to guide the transformation of student applicants into competent clinicians.
Peter Sean Staats is an American physician, specializing in interventional pain medicine. He is the founder of the Division of Pain Medicine at the Johns Hopkins School of Medicine, and was the Division's chief for nearly a decade. He is a past president of the North American Neuromodulation Society, the New Jersey Society of Interventional Pain Medicine,the American Society of Interventional Pain Physicians ( ASIPP) the World Institute of Pain ( WIP), The Southern Pain Society.
Chi Ho Ban Tsui is a Canadian anesthesiologist known for medical innovation in the field of anesthesia. Examples include describing the Tsui Test and developing the StimuLong Sono-Tsui for ease of pediatric epidural placement. Recently along with his son, Dr. Jonathan Jenkin Tsui, Dr. Tsui developed a catheter-over-needle kit allowing a continuous catheter placement to be performed with the ease of a single shot during peripheral nerve blocks.
The SUNY Downstate Health Sciences University is a public medical school in New York City and one of the three components of SUNY Downstate Health Sciences University: University Hospital at Long Island College Hospital, SUNY Downstate at Bay Ridge, and University Hospital of Brooklyn in East Flatbush, whose staffing is provided by SUNY Downstate College of Medicine.
Kathryn Ann Kelly "Kelly" McQueen is an American anesthesiologist and global health expert. She currently practices anesthesiology at the UW Health University Hospital in Madison, Wisconsin and serves as the chair for the Department of Anesthesiology at the University of Wisconsin School of Medicine and Public health.
Vitaly Napadow is a Ukrainian-born American neuroscientist and acupuncturist. He is a full professor of Physical Medicine & Rehabilitation and Radiology at Harvard Medical School. He is also the Director of the Scott Schoen and Nancy Adams Discovery Center for Recovery from Chronic Pain at Spaulding Rehabilitation Hospital and Director of the Center for Integrative Pain NeuroImaging at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital. He is a former president of the Society for Acupuncture Research. He has been a pain neuroimaging researcher for more than 20 years. Somatosensory, cognitive, and affective factors all influence the malleable experience of chronic pain, and Dr. Napadow’s Lab has applied human functional and structural neuroimaging to localize and suggest mechanisms by which different brain circuitries modulate pain perception. Dr. Napadow’s neuroimaging research also aims to better understand how non-pharmacological therapies, from acupuncture and transcutaneous neuromodulation to cognitive behavioral therapy and mindfulness meditation training, ameliorate aversive perceptual states such as pain. In fact, his early career was known for researching acupuncture and its effects on the brain. He has also researched the brain circuitry underlying nausea and itch. He is also known for developing a novel approach in applying measures of resting state brain connectivity as potential biomarkers for spontaneous clinical pain in chronic pain disorders such as fibromyalgia.
Beth Darnall is American scientist, pain psychologist, author, and Associate Professor of Anesthesiology, Perioperative and Pain Medicine at Stanford University where she directs the Stanford Pain Relief Innovations Lab. From 2005 to 2012, Darnall was an assistant professor and associate professor at Oregon Health & Science University.
Alex Bekker is a physician, author and academic. He is a professor and chair at the Department of Anesthesiology, Rutgers New Jersey Medical School. He is also professor at the Department of Physiology, Pharmacology & Neurosciences. He serves as the Chief of Anesthesiology Service at the University Hospital in Newark.
Lee Alan Fleisher is an American anesthesiologist. In 2020, Fleisher was named Chief Medical Officer and Director of the Centers for Medicare & Medicaid Services Center for Clinical Standards and Quality. He previously served as Chair of Anesthesiology and Critical Care at the Perelman School of Medicine at the University of Pennsylvania.
Alex Macario is an American anesthesiologist, academic and author. He is a vice-chair for education, a professor in the Department of Anesthesiology, Perioperative and Pain Medicine, and program director for the anesthesiology residency at Stanford University School of Medicine.
Talmage D. Egan is an anesthesiologist, academic, entrepreneur, and author. He is a professor and chair in the department of anesthesiology, and an adjunct professor in the departments of pharmaceutics, bioengineering, and neurosurgery at the University of Utah School of Medicine.
