Stacey Finley

Last updated
Stacey Finley
Stacey-Finley.jpg
Born
Alma mater Northwestern University
Florida A & M University
Scientific career
Institutions University of Southern California
Johns Hopkins University
Thesis Computational approaches to systems biology: Applications in xenobiotic metabolism and cellular signaling [1]  (2009)
Doctoral advisor Linda Broadbelt
Website CSBL

Stacey Finley is the Nichole A. and Thuan Q. Pham Professor and professor of biomedical engineering, chemical engineering and materials science, and quantitative and computational biology at the University of Southern California. [2] Finley has a joint appointment in the department of chemical engineering and materials science, and she is a member of the USC Norris Comprehensive Cancer Center. Finley is also a standing member of the MABS Study Section at NIH. Her research has been supported by grants from the NSF, NIH, and American Cancer Society.

Contents

Early life and education

Finley held an interest in science and math since an early age and so pursued engineering, stating that it was an "analytical decision" for her: "I had this equation -- what am I good at, what am I interested in, and how do those things fit together?" [3] Finley studied chemical engineering at Florida A&M University, graduating summa cum laude. [4] She went on to study at Northwestern University for her graduate program, working with Linda Broadbelt and Vassily Hatzimanikatis. During her doctorate she developed a computational framework, BNICE, to predict novel biodegradation pathways with applications for bioremediation. [5] Finley was a postdoctoral fellow at Johns Hopkins University, where she worked with Aleksander S. Popel. There she studied the signaling pathways of VEGF, a protein that contributes to angiogenesis. She created a physiologically-based computational framework to study VEGF kinetics and transport that can better inform cancer therapies. [6]

Research and career

Finley started her computational systems biology lab at USC Viterbi in 2013. Her lab leverages computational models to interrogate angiogenesis, metabolism, and immunotherapy. Finley's lab has built mathematical models to predict CAR T cell response to variations in protein expression. [7]

In 2017 Finley was appointed the Gordon S. Marshall Early Career Chair Director for Computational Modeling of Cancer. She is also an active participant in increasing diversity in STEM, either by visiting middle and high schools or through panels to encourage under-represented minorities to pursue STEM careers. [4] [8]

In 2022, she served as a visiting professor at EPFL - École polytechnique fédérale de Lausanne. [9]

Awards and honors

Her awards and honors include:

References

  1. "Computational approaches to systems biology: Applications in xenobiotic metabolism and cellular signaling". ProQuest   304971872 . Retrieved 2023-03-01.
  2. "USC - Viterbi School of Engineering - Viterbi Faculty Directory". viterbi.usc.edu. Retrieved 2026-02-04.
  3. "USC - Viterbi School of Engineering - Counting Toward a Cancer Cure". viterbi.usc.edu. Retrieved 2021-06-17.
  4. 1 2 "Emerging Scholars | Diverse". diverseeducation.com. Retrieved 2021-06-17.
  5. Finley, Stacey D.; Broadbelt, Linda J.; Hatzimanikatis, Vassily (2009-12-15). "Computational Framework for Predictive Biodegradation". Biotechnology and Bioengineering. 104 (6): 1086–1097. doi:10.1002/bit.22489. ISSN   0006-3592. PMC   4073782 . PMID   19650084.
  6. Finley, Stacey D.; Popel, Aleksander S. (2013-06-05). "Effect of Tumor Microenvironment on Tumor VEGF During Anti-VEGF Treatment: Systems Biology Predictions". JNCI: Journal of the National Cancer Institute. 105 (11): 802–811. doi:10.1093/jnci/djt093. ISSN   0027-8874. PMC   3672077 . PMID   23670728.
  7. Cess, Colin G.; Finley, Stacey D. (2020-03-21). "Data-driven analysis of a mechanistic model of CAR T cell signaling predicts effects of cell-to-cell heterogeneity". Journal of Theoretical Biology. 489 110125. Bibcode:2020JThBi.48910125C. doi:10.1016/j.jtbi.2019.110125. ISSN   0022-5193. PMC   7467855 . PMID   31866395.
  8. "Outreach | Computational Systems Biology Laboratory" . Retrieved 2021-06-17.
  9. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 "Finley Lab Website".
  10. 1 2 3 4 5 "Viterbi Faculty Directory" . Retrieved 2023-03-01.
  11. "NSF Award Search: Award # 1552065 - CAREER: Mathematical modeling of angiogenesis signaling and crosstalk in tumor cells". www.nsf.gov. Retrieved 2021-06-17.
  12. "Stacey Finley selected as AACR NextGen Star". USC Viterbi | Department of Biomedical Engineering. 2017-12-05. Retrieved 2021-06-17.
  13. "Stacey D. Finley, Ph.D. COF-6050 - AIMBE" . Retrieved 2021-06-17.