Stimulator of chondrogenesis 1

SCRG1
Identifiers
Aliases	SCRG1 , SCRG-1, stimulator of chondrogenesis 1
External IDs	OMIM: 603163 MGI: 1328308 HomoloGene: 5269 GeneCards: SCRG1
Gene location (Human)
Chr.	Chromosome 4 (human)
End	173,406,380 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	57,477,585 bp
Gene ontology
Molecular function	• GO:0001948 protein binding ;
Cellular component	• Golgi apparatus ; • neuron projection terminus ; • extracellular region ; • cytoplasm ; • extracellular space ;
Biological process	• nervous system development ;
	Sources:Amigo / QuickGO
Orthologs
	11341
	20284
	ENSG00000164106
	ENSMUSG00000031610
	O75711
	O88745
	NM_007281 ; NM_001329597
	NM_009136
	NP_001316526 ; NP_009212
	NP_033162
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated May 16, 2021

Stimulator of chondrogenesis 1 is a protein that in humans is encoded by the SCRG1 gene. ^[5]

Function

Scrapie-responsive gene 1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The scrapie responsive protein 1 may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus. In addition, the encoded protein can interact with bone marrow stromal cell antigen 1 (BST1) to enhance the differentiation potentials of human mesenchymal stem cells during tissue and bone regeneration. [provided by RefSeq, Jul 2016].

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000164106 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000031610 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Stimulator of chondrogenesis 1" . Retrieved 2018-10-01.

Stimulator of chondrogenesis 1

Contents

Function

Related Research Articles

References

Further reading