Susan Smalley

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Susan Smalley
SueSmalley.jpg
Born
Minneapolis, Minnesota, U.S.
NationalityAmerican
EducationUniversity of Michigan, BA, Anthropology, 1976
University of California, Los Angeles, MA, Anthropology, 1981
University of California, Ph.D, Anthropology, 1985
Occupation(s)Behavioral Geneticist, Writer, Activist, Investor
Known forGenetics of attention deficit hyperactivity Disorder (ADHD) and autism spectrum disorders
Mindfulness meditation
Spouse Kevin Wall
Scientific career
FieldsBehavioral genetics
mindfulness
InstitutionsUniversity of California, Los Angeles
Thesis Genetic influences on spatial ability: Transmission in an extended kindred (1985)
Website www.suesmalley.com

Susan Smalley is an American behavioral geneticist, writer and activist. The co-author of Fully Present: The Science, Art, and Practice of Mindfulness, she is the founder of the UCLA Mindful Awareness Research Center at the Jane and Terry Semel Institute for Neuroscience and Human Behavior (MARC), and professor emerita in the department of psychiatry and biobehavioral sciences at UCLA. Her research centers on the genetic basis of childhood-onset behavior disorders, such as ADHD, [1] and the cognitive and emotional impact of mindfulness meditation on health and wellbeing. [2] [3] She has published more than 100 peer-reviewed papers and lectured globally on the genetics of human behavior and the science of mindfulness. [4]

Contents

Career

PTK Capital

Smalley is the co-founder of PTK Capital, an investment fund that invests in early stage companies and venture capital funds. The firm's investment activities focus on transformative companies in the areas of Entertainment, Food and Wellness. PTK Capital supports "people and ideas with the potential to significantly benefit the human condition."

Smalley is also on the scientific advisory board for Stop Breathe and Think, an app for emotional well-being; [5] and the board of directors for Equality Now, an international human rights organization focused on women and girls; [6] and was honored by Equality Now in December 2019. [7]

UCLA, ADHD and behavior genetics

Smalley joined the faculty at UCLA after she completed post-doctoral fellowships in medical genetics and childhood psychopathology, moving from assistant to full professor until her retirement to emeritus in 2011. [8]

In 1988 she published a review paper on the genetics of autism in JAMA Psychiatry . Following its publication, she received a National Institute of Health (NIH) grant to investigate genetic determinants in autism, and pioneered an approach to behavioral genetics by studying known genetic disorders with behavioral sequelae, specifically, the study of tuberous sclerosis complex (TSC), a genetic disorder in which autistic disorder occurs at higher rates than the general population. [9] She continued to research autism for the following ten years, producing numerous papers on the genetics and subclinical variants of autism beyond the diagnostic classification as well as genetic and behavioral studies of TSC. [2]

Smalley's focus subsequently shifted to ADHD. Her lab produced more than 40 publications on the disorder, including the first genome-wide scan (in conjunction with investigators at Oxford University), [10] candidate gene investigations, [11] and a series of papers on ADHD among a northern Finnish birth cohort. [12] She wrote extensively on the strengths of those with ADHD, characterizing it as a different way of thinking rather than a deficit. [13]

Mindful awareness

Smalley was diagnosed with an early stage melanoma in 2002. She took a leave of absence to explore non-western wellness practices, and in addition to significant lifestyle changes, she developed a meditation practice. When she returned to UCLA, she began researching mindfulness meditation and its impact on ADHD and other disorders. She subsequently led seminal studies that demonstrated the relationship between mindfulness and common personality traits of those with ADHD, mindfulness as an intervention in ADHD, and school-based approaches to bringing mindfulness to children. [14]

Smalley founded the Mindful Awareness Research Center at the UCLA Semel Institute for Neuroscience and Human Behavior (MARC) to bring meditation practices to the general public through research and education. [15] In an article for the Huffington Post , she wrote: "As a scientist, I love the challenge of understanding my mind, from the inside, while learning what science tells us from the outside. The merging of these two approaches will yield knowledge far greater than either can alone." [16]

In 2010, Smalley and Diana Winston, a former Buddhist nun and the director of education at MARC, wrote Fully Present: The Science, Art, and Practice of Mindfulness. [17] It explores the science of meditation and provides guidance to develop a mindfulness practice. [18]

Smalley also writes regularly for the Huffington Post and Psychology Today. [19] She was the keynote speaker at the UCLA Department of Anthropology commencement ceremony in 2013, and the 2017 Children and Adults with Attention Deficit Hyperactivity Disorder (CHADD) annual conference. [20] [21]

Education

Smalley majored in biological anthropology at the University of Michigan, and as an undergraduate became interested in population genetics and human evolution. She received a BA in anthropology in 1976, and in 1981 earned an MA in anthropology from UCLA. She was awarded a Ph.D. in anthropology with specialization in population genetics from UCLA in 1985. Her dissertation examined the genetics of spatial ability. [8]

Personal life

Smalley is married to Kevin Wall, an entrepreneur, activist, and investor. They have three children. [22]

Selected publications

Mindful Awareness

Behavior Genetics and ADHD

Gender Equality

Related Research Articles

<span class="mw-page-title-main">Causes of mental disorders</span> Etiology of psychopathology

A mental disorder is an impairment of the mind disrupting normal thinking, feeling, mood, behavior, or social interactions, and accompanied by significant distress or dysfunction. The causes of mental disorders are very complex and vary depending on the particular disorder and the individual. Although the causes of most mental disorders are not fully understood, researchers have identified a variety of biological, psychological, and environmental factors that can contribute to the development or progression of mental disorders. Most mental disorders result in a combination of several different factors rather than just a single factor.

<span class="mw-page-title-main">Attention deficit hyperactivity disorder</span> Neurodevelopmental disorder

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by executive dysfunction occasioning symptoms of inattention, hyperactivity, impulsivity and emotional dysregulation that are excessive and pervasive, impairing in multiple contexts, and otherwise age-inappropriate.

Developmental disorders comprise a group of psychiatric conditions originating in childhood that involve serious impairment in different areas. There are several ways of using this term. The most narrow concept is used in the category "Specific Disorders of Psychological Development" in the ICD-10. These disorders comprise developmental language disorder, learning disorders, motor disorders, and autism spectrum disorders. In broader definitions ADHD is included, and the term used is neurodevelopmental disorders. Yet others include antisocial behavior and schizophrenia that begins in childhood and continues through life. However, these two latter conditions are not as stable as the other developmental disorders, and there is not the same evidence of a shared genetic liability.

<span class="mw-page-title-main">Hyperfocus</span> Intense form of mental concentration

Hyperfocus is an intense form of mental concentration or visualization that focuses consciousness on a subject, topic, or task. In some individuals, various subjects or topics may also include daydreams, concepts, fiction, the imagination, and other objects of the mind. Hyperfocus on a certain subject can cause side-tracking away from assigned or important tasks.

Adult Attention Deficit Hyperactivity Disorder is the persistence of attention deficit hyperactivity disorder (ADHD) in adults. It is a neurodevelopmental disorder, meaning symptoms must have been present in childhood except for when ADHD occurs after a traumatic brain injury. Specifically, multiple symptoms must be present before the age of 12, according to DSM-5 diagnostic criteria. The cutoff age of 12 is a change from the previous requirement of symptom onset, which was before the age of 7 in the DSM-IV. This was done to add flexibility in the diagnosis of adults. ADHD was previously thought to be a childhood disorder that improved with age, but recent research has disproved this. Approximately two-thirds of childhood cases of ADHD continue into adulthood, with varying degrees of symptom severity that change over time, and continue to affect individuals with symptoms ranging from minor inconveniences to impairments in daily functioning.

The hunter versus farmer hypothesis is a proposed explanation of the nature of attention-deficit hyperactivity disorder (ADHD) first suggested by radio host Thom Hartmann in his book Attention Deficit Disorder: A Different Perception. This hypothesis proposes that ADHD represents a lack of adaptation of members of hunter-gatherer societies to their transformation into farming societies. Hartmann developed the idea first as a mental model after his own son was diagnosed with ADHD, stating, "It's not hard science, and was never intended to be."

Cognitive disengagement syndrome (CDS) is an attention syndrome characterised by prominent dreaminess, mental fogginess, hypoactivity, sluggishness, slow reaction time, staring frequently, inconsistent alertness, and a slow working speed. To scientists in the field, it has reached the threshold of evidence and recognition as a distinct syndrome.

<span class="mw-page-title-main">Attention deficit hyperactivity disorder controversies</span> Controversies surrounding the topic of ADHDs nature, diagnosis, and treatment

Despite the scientifically well-established nature of attention deficit hyperactivity disorder (ADHD), its diagnosis, and its treatment, each of these has been controversial since the 1970s. The controversies involve clinicians, teachers, policymakers, parents, and the media. Positions range from the view that ADHD is within the normal range of behavior to the hypothesis that ADHD is a genetic condition. Other areas of controversy include the use of stimulant medications in children, the method of diagnosis, and the possibility of overdiagnosis. In 2009, the National Institute for Health and Care Excellence, while acknowledging the controversy, stated that the current treatments and methods of diagnosis are based on the dominant view of the academic literature.

In psychology and neuroscience, executive dysfunction, or executive function deficit, is a disruption to the efficacy of the executive functions, which is a group of cognitive processes that regulate, control, and manage other cognitive processes. Executive dysfunction can refer to both neurocognitive deficits and behavioural symptoms. It is implicated in numerous psychopathologies and mental disorders, as well as short-term and long-term changes in non-clinical executive control. Executive dysfunction is the mechanism underlying ADHD Paralysis, and in a broader context, it can encompass other cognitive difficulties like planning, organizing, initiating tasks and regulating emotions. It is a core characteristic of ADHD and can elucidate numerous other recognized symptoms.

<span class="mw-page-title-main">Susan Kaiser Greenland</span> American author and teacher

Susan Kaiser Greenland is an American author and teacher of mindfulness and meditation, practicing a state of present-moment awareness to develop overall attentiveness and social/emotional skills. Susan played a foundational role in making mindfulness practices developmentally appropriate for young people, and with her first book The Mindful Child she helped pioneer activity-based mindfulness. This technique is now practiced in American schools throughout the country to help children learn how to reduce and alleviate their stress levels.

<span class="mw-page-title-main">Sotos syndrome</span> Genetic overgrowth disorder

Sotos syndrome is a rare genetic disorder characterized by excessive physical growth during the first years of life. Excessive growth often starts in infancy and continues into the early teen years. The disorder may be accompanied by autism, mild intellectual disability, delayed motor, cognitive, and social development, hypotonia, and speech impairments. Children with Sotos syndrome tend to be large at birth and are often taller, heavier, and have relatively large skulls (macrocephaly) than is normal for their age. Signs of the disorder, which vary among individuals, include a disproportionately large skull with a slightly protrusive forehead, large hands and feet, large mandible, hypertelorism, and downslanting eyes. Clumsiness, an awkward gait, and unusual aggressiveness or irritability may also occur.

<span class="mw-page-title-main">Metadoxine</span> Medication used for alcohol intoxication

Metadoxine, also known as pyridoxine-pyrrolidone carboxylate, is a drug used to treat chronic and acute alcohol intoxication. Metadoxine accelerates alcohol clearance from the blood.

<span class="mw-page-title-main">Katya Rubia</span> British neuroscentist

Katya Rubia is a professor of Cognitive Neuroscience at the MRC Social, Genetic and Developmental Psychiatry Centre and Department of Child and Adolescent Psychiatry, both part of the Institute of Psychiatry, King's College London.

Virginia I. Douglas was a Canadian psychologist. She was a professor at McGill University in Montreal, Canada, noted for her contributions to the study of attention deficit hyperactivity disorder (ADHD).

<span class="mw-page-title-main">Stephen P. Hinshaw</span> American psychologist

Stephen P. Hinshaw is an American psychologist whose contributions lie in the areas of developmental psychopathology and combating the stigma that surrounds mental illness. He has authored more than 325 scientific articles and chapters as well as 14 authored and edited books. Currently, he is Professor in the Department of Psychology at the University of California, Berkeley, and Professor In Residence and Vice Chair for Child and Adolescent Psychology in the Department of Psychiatry at the University of California, San Francisco. His work focuses on child and adolescent mental disorders, clinical interventions, mechanisms of change in psychopathology, and stigma prevention efforts, with a specialization in ADHD and other neurodevelopmental disorders.

Susan Shur-Fen Gau, also known as Susan Gau, Shur-Fen Gau, Gau Shur-Fen and in Chinese:高淑芬, is a Taiwanese psychiatrist and academic with specialized in psychiatry, psychology, epidemiology, preventive medicine, occupational therapy, and brain and mind sciences.

Benjamin Michael Neale is a statistical geneticist with a specialty in psychiatric genetics. He is an institute member at the Broad Institute as well as an associate professor at both Harvard Medical School and the Analytic and Translational Genetics Unit at Massachusetts General Hospital. Neale specializes in genome-wide association studies (GWAS). He was responsible for the data analysis of the first GWAS on attention-deficit/hyperactivity-disorder, and he developed new analysis software such as PLINK, which allows for whole-genome data to be analyzed for specific gene markers. Related to his work on GWAS, Neale is the lead of the ADHD psychiatric genetics and also a member of the Psychiatric GWAS Consortium analysis committee.

Susan Y. Bookheimer is a professor of clinical neuroscience at UCLA School of Medicine. She is best known for her work developing brain imaging techniques to help patients with Alzheimer's disease, autism, attention deficit hyperactivity disorder, brain tumors, and epilepsy.

Deaf and hard of hearing individuals with additional disabilities are referred to as "Deaf Plus" or "Deaf+". Deaf children with one or more co-occurring disabilities could also be referred to as hearing loss plus additional disabilities or Deafness and Diversity (D.A.D.). About 40–50% of deaf children experience one or more additional disabilities, with learning disabilities, intellectual disabilities, autism spectrum disorder (ASD), and visual impairments being the four most concomitant disabilities. Approximately 7–8% of deaf children have a learning disability. Deaf plus individuals utilize various language modalities to best fit their communication needs.

<span class="mw-page-title-main">Jan K. Buitelaar</span>

Jan K. Buitelaar is a Dutch medical doctor, psychiatrist, author, and academic. He is a professor of psychiatry and child and adolescent psychiatry at Radboud University Medical Centre and former Head of Child and Adolescent Psychiatry at Karakter Child and Adolescent Psychiatry.

References

  1. McGough, Robert (October 22, 2002). "General Location of Gene Linked to ADHD Is Found". The Wall Street Journal. Retrieved March 12, 2018.
  2. 1 2 Baruchin, Aliyah (2008-03-13). "Nature, Nurture and Attention Deficit". The New York Times. ISSN   0362-4331 . Retrieved 2018-03-08.
  3. Goleman, Daniel. "Exercising the Mind to Treat Attention Deficits". New York Times. Retrieved 2018-03-08.
  4. "Research and Publications, Susan Smalley, Ph.D." scholar.google.com. Retrieved 2018-03-08.
  5. "Stop, Breathe & Think: A New Meditation App To Boost Compassion And Creativity". Fast Company. 2014-01-16. Retrieved 2018-02-22.
  6. "Susan Smalley, PhD (USA)". Equality Now. 2016-03-08. Retrieved 2018-03-08.
  7. "Sue Smalley, Ph.D. - Equality Now's 2018 Make Equality Reality Gala", Equality Now
  8. 1 2 "Sue Smalley at the University of California, Los Angeles". ucla.academia.edu. Retrieved 2018-03-08.
  9. Smalley, Susan. "Detection of Susceptibility Genes in Adhd". NIH Grants.
  10. "UCLA Geneticists Find Location Of Major Gene In ADHD; Targeted Region Also Linked To Autism". ScienceDaily. Retrieved 2018-03-12.
  11. "The DRD4 Gene: Psychiatry's Repeat Offender". Genome News Network. Retrieved 2018-03-08.
  12. Healy, Melissa (2008-01-28). "Growing up with, and out of, ADHD". Los Angeles Times. ISSN   0458-3035 . Retrieved 2018-03-08.
  13. Hallowell, Edward M. (2006-02-26). "ADD's black box scare". Los Angeles Times. ISSN   0458-3035 . Retrieved 2018-02-16.
  14. Fitzgerald, Patricia, Dr (2009-08-15). "What Inspired A Scientist To Open A Meditation Center At UCLA?". Huffington Post. Retrieved 2018-03-08.{{cite web}}: CS1 maint: multiple names: authors list (link)
  15. Brown, Patricia Leigh (2007-06-16). "In the Classroom, a New Focus on Quieting the Mind". The New York Times. ISSN   0362-4331 . Retrieved 2018-03-08.
  16. Smalley, Susan (2007-09-18). "Mindfulness And Meditation In The Modern World". Huffington Post. Retrieved 2018-02-22.
  17. Wilson, Jeff. Mindful America: the Mutual Transformation of Buddhist Meditation and American culture. New York. ISBN   9780199827824. OCLC   874557219.
  18. "Nonfiction Book Review: Fully Present: The Science, Art, and Practice of Mindfulness by Susan Smalley and Diana Winston". PublishersWeekly.com. Retrieved 2018-02-22.
  19. "Susan L. Smalley". Psychology Today. Retrieved 2018-03-08.
  20. ADHD, CHADD – The National Resource on. "General Conference Handout | CHADD Annual Conference". chadd.org. Retrieved 2018-03-08.
  21. "2013 College Report" (PDF). UCLA College Report. May 21, 2013. p. 21. Retrieved March 7, 2018.
  22. Smalley, Sue (2014-09-16). "Standing on Ceremony". Los Angeles Times. Retrieved 2023-06-22.