TKTL2

TKTL2
Identifiers
Aliases	TKTL2 , transketolase like 2
External IDs	MGI: 1921669; HomoloGene: 69456; GeneCards: TKTL2; OMA:TKTL2 - orthologs
Gene location (Human) Chr. Chromosome 4 (human) [1] Band 4q32.2 Start 163,471,095 bp [1] End 163,473,754 bp [1]
Gene location (Mouse) Chr. Chromosome 8 (mouse) [2] Band 8|8 B3.1 Start 66,964,408 bp [2] End 66,970,987 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm left testis right testis gonad monocyte lymph node human musculoskeletal system connective tissue adipose tissue muscular system Top expressed in spermatocyte spermatid secondary oocyte zygote seminiferous tubule primary oocyte blastocyst yolk sac More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity catalytic activity metal ion binding transketolase activity Cellular component cytoplasm Biological process metabolism Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84076 74419 Ensembl ENSG00000151005 ENSMUSG00000025519 UniProt Q9H0I9 Q9D4D4 RefSeq (mRNA) NM_032136 NM_001271574 NM_028927 RefSeq (protein) NP_115512 NP_001258503 NP_083203 Location (UCSC) Chr 4: 163.47 – 163.47 Mb Chr 8: 66.96 – 66.97 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Transketolase-like protein 2 is an enzyme that in humans is encoded by the TKTL2 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000151005 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000025519 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
6. "Entrez Gene: TKTL2 transketolase-like 2".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.