Tadeusz Pacholczyk (born 1964) is an American Roman Catholic priest, neuroscientist and writer. [1]
Pacholczyk grew up in Tucson, Arizona to a Polish family. [2] His father Andrzej Pacholczyk [3] was a professor of astrophysics at the University of Arizona. He earned his doctorate in neuroscience from Yale University where he determined the gene sequence for the human norepinephrine transporter, [4] [5] which demonstrated significant amino-acid identity with the GABA transporter, thus identifying a new gene family for neurotransmitter transporter proteins. [6] He did post-doctoral research at Harvard University and Massachusetts General Hospital where his work focused on structural studies of the Na,K-ATPase. [7]
In 1999, he was ordained a priest, after studying in Rome. He quickly became a church spokesman on what he calls beginning-of-life and end-of-life issues. He is a proponent of the teachings of the Catholic Church in opposition to human cloning and embryonic stem cell research. [8] [9] (See Declaration on the Production and the Scientific and Therapeutic Use of Human Embryonic Stem Cells.) He has testified before state legislatures and been quoted in the press. [10] Pacholczyk writes a nationally-syndicated column, titled "Making Sense of Bioethics," that appears in numerous Catholic diocesan newspapers in the United States and has been reprinted in newspapers in Canada, England, Poland, and Australia. [11] [12] He has written on a broad range of medical ethical issues, [13] including ethical prescription and use of opioids, [14] use of performance-enhancing drugs in professional athletics, [15] animal/human hybrids, [13] artificial nutrition and hydration, [13] conscience rights for health care providers and patients, [13] in vitro fertilization, [13] palliative and hospice care, [13] and physician-assisted suicide. [13] Since 2001, he has given several hundred presentations [16] and invited lectures, [17] and continues to speak widely on contemporary bioethical themes throughout the U.S., Canada, and Europe. In July 2020, he was appointed by United States Secretary of Health and Human Services Alex Azar to serve on the National Institute of Health Human Fetal Tissue Research Ethics Advisory Board. [18] [10]
As of 2024 [update] , Pacholczyk is a priest of the Diocese of Fall River, [7] Massachusetts. He served as the director of education from 2003 to 2023, and currently serves as senior ethicist at The National Catholic Bioethics Center in Philadelphia, [19] whose long-time president, John Haas (retired 2019), served as an ordinary member of the Pontifical Academy for Life.
On October 7, 2012, Pacholczyk wrote a piece in the Wall Street Journal titled "Please Step Back From the Assisted-Suicide Ledge" [20] in which he notes, "If physician-assisted suicide really represents a good choice, we need to ask: Why should only physicians be able to participate?" He follows the rhetorical question to its conclusion by noting, "Why should doctors have a monopoly on undermining public trust? Police and lifeguards could help out too."
On October 22, 2018, Pacholczyk wrote a piece in the Catholic Herald titled "Sexual Orientation: Hope for restoration and healing with SOCE" (Sexual Orientation Change Efforts). [21] He describes the measured conclusion of a review by Peter Sprigg, Senior Fellow for Policy Studies at the Family Research Council in Washington, D.C. of six studies published between 2000 and 2018 which concludes that SOCE "can be effective for some clients in bringing about significant change in some components of sexual orientation", and that "few harms were reported".
In December 2001, Pacholczyk testified before the Massachusetts Senate that "embryonic human life is inviolable and deserving of unconditional respect." [22] On January 10, 2020, he wrote a piece in The Boston Pilot titled "The Foxes and the Henhouse" [23] in which he discusses the production of two gene-edited human babies in China, and the apparent inability of the scientific establishment to provide adequate ethical regulation and oversight of research involving embryonic humans.
Pacholczyk has written and commented about the ethics of COVID-19 vaccines and COVID-19 treatments. [24] [25] [12] [26] [27] His writings and comments have addressed issues such as the rationing of medical care (such as ventilators), [27] whether and when prisoners should be given priority to receive vaccinations for COVID-19, [24] whether public health officials can make it mandatory for people to receive a vaccine, [26] and whether medical treatments and vaccines derived from cell lines derived from aborted fetuses are ethical. [25] [12]
Human cloning is the creation of a genetically identical copy of a human. The term is generally used to refer to artificial human cloning, which is the reproduction of human cells and tissue. It does not refer to the natural conception and delivery of identical twins. The possibilities of human cloning have raised controversies. These ethical concerns have prompted several nations to pass laws regarding human cloning.
In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type.
Bioethics is both a field of study and professional practice, interested in ethical issues related to health, including those emerging from advances in biology, medicine, and technologies. It proposes the discussion about moral discernment in society and it is often related to medical policy and practice, but also to broader questions as environment, well-being and public health. Bioethics is concerned with the ethical questions that arise in the relationships among life sciences, biotechnology, medicine, politics, law, theology and philosophy. It includes the study of values relating to primary care, other branches of medicine, ethical education in science, animal, and environmental ethics, and public health.
Medical ethics is an applied branch of ethics which analyzes the practice of clinical medicine and related scientific research. Medical ethics is based on a set of values that professionals can refer to in the case of any confusion or conflict. These values include the respect for autonomy, non-maleficence, beneficence, and justice. Such tenets may allow doctors, care providers, and families to create a treatment plan and work towards the same common goal. These four values are not ranked in order of importance or relevance and they all encompass values pertaining to medical ethics. However, a conflict may arise leading to the need for hierarchy in an ethical system, such that some moral elements overrule others with the purpose of applying the best moral judgement to a difficult medical situation. Medical ethics is particularly relevant in decisions regarding involuntary treatment and involuntary commitment.
In philosophy and neuroscience, neuroethics is the study of both the ethics of neuroscience and the neuroscience of ethics. The ethics of neuroscience concerns the ethical, legal, and social impact of neuroscience, including the ways in which neurotechnology can be used to predict or alter human behavior and "the implications of our mechanistic understanding of brain function for society... integrating neuroscientific knowledge with ethical and social thought".
Arthur L. Caplan is an American ethicist and professor of bioethics at New York University Grossman School of Medicine.
Leon Richard Kass is an American physician, scientist, educator, and public intellectual. Kass is best known as a proponent of liberal arts education via the "Great Books," as a critic of human cloning, life extension, euthanasia and embryo research, and for his tenure as chairman of the President's Council on Bioethics from 2001 to 2005. Although Kass is often referred to as a bioethicist, he eschews the term and refers to himself as "an old-fashioned humanist. A humanist is concerned broadly with all aspects of human life, not just the ethical."
Human embryonic kidney 293 cells, also often referred to as HEK 293, HEK-293, 293 cells, are an immortalised cell line derived from HEK cells isolated from a female fetus in the 1970s.
A designer baby is a baby whose genetic makeup has been selected or altered, often to exclude a particular gene or to remove genes associated with disease. This process usually involves analysing a wide range of human embryos to identify genes associated with particular diseases and characteristics, and selecting embryos that have the desired genetic makeup; a process known as preimplantation genetic diagnosis. Screening for single genes is commonly practiced, and polygenic screening is offered by a few companies. Other methods by which a baby's genetic information can be altered involve directly editing the genome before birth, which is not routinely performed and only one instance of this is known to have occurred as of 2019, where Chinese twins Lulu and Nana were edited as embryos, causing widespread criticism.
The stem cell controversy concerns the ethics of research involving the development and use of human embryos. Most commonly, this controversy focuses on embryonic stem cells. Not all stem cell research involves human embryos. For example, adult stem cells, amniotic stem cells, and induced pluripotent stem cells do not involve creating, using, or destroying human embryos, and thus are minimally, if at all, controversial. Many less controversial sources of acquiring stem cells include using cells from the umbilical cord, breast milk, and bone marrow, which are not pluripotent.
Mumps vaccines are vaccines which prevent mumps. When given to a majority of the population they decrease complications at the population level. Effectiveness when 90% of a population is vaccinated is estimated at 85%. Two doses are required for long term prevention. The initial dose is recommended between 12 and 18 months of age. The second dose is then typically given between two years and six years of age. Usage after exposure in those not already immune may be useful.
The National Catholic Bioethics Center (NCBC) is a not-for-profit research center located in Philadelphia, Pennsylvania, after previous locations in St. Louis (1972–1985) and Boston (1985–2004). Its mission is "to uphold the dignity of the human person in health care and biomedical research, thereby sharing in the ministry of Jesus Christ and his Church." The chairman of the Board of Directors is Gregory M. Aymond, Archbishop of New Orleans. The Center publishes Ethics & Medics monthly and The National Catholic Bioethics Quarterly, as well as books including the Handbook on Critical Life Issues.
Paul Rodney McHugh is an American psychiatrist, researcher, and educator. He is currently the University Distinguished Service Professor of Psychiatry at the Johns Hopkins University School of Medicine, where he was previously the Henry Phipps Professor and director from 1975 to 2001.
The laws and policies regarding stem cell research in the People's Republic of China are relatively relaxed in comparison to that of other nations. The reason for this is due to different traditional and cultural views in relation to that of the West.
A biological patent is a patent on an invention in the field of biology that by law allows the patent holder to exclude others from making, using, selling, or importing the protected invention for a limited period of time. The scope and reach of biological patents vary among jurisdictions, and may include biological technology and products, genetically modified organisms and genetic material. The applicability of patents to substances and processes wholly or partially natural in origin is a subject of debate.
Françoise Elvina BaylisFISC is a Canadian bioethicist whose work is at the intersection of applied ethics, health policy, and practice. The focus of her research is on issues of women's health and assisted reproductive technologies, but her research and publication record also extend to such topics as research involving humans, gene editing, novel genetic technologies, public health, the role of bioethics consultants, and neuroethics. Baylis' interest in the impact of bioethics on health and public policy as well as her commitment to citizen engagement]and participatory democracy sees her engage with print, radio, television, and other online publications.
S. Matthew Liao is a Taiwanese-American philosopher specializing in bioethics and normative ethics. Liao currently holds the Arthur Zitrin Chair of Bioethics, and is the Director of the Center for Bioethics and Affiliated Professor in the Department of Philosophy at New York University. He has previously held appointments at Oxford, Johns Hopkins, Georgetown, and Princeton.
The use of fetal tissue in vaccine development is the practice of researching, developing, and producing vaccines through growing viruses in cultured (laboratory-grown) cells that were originally derived from human fetal tissue. Since the cell strains in use originate from abortions, there has been opposition to the practice and the resulting vaccines on religious and moral grounds.
Nir Eyal is a bioethicist and Henry Rutgers Professor of Bioethics and Director of the Center for Population–Level Bioethics at Rutgers University in New Jersey. He was formerly a bioethicist in the Department of Global Health and Population of the Harvard T.H. Chan School of Public Health and the Department of Global Health and Social Medicine of the Harvard Medical School. He has long worked closely with Harvard bioethicist Daniel Wikler. Eyal's current visibility concerns his role in studying the ethics of human challenge trials in HIV, malaria, and coronavirus vaccine development. He has also written on 'bystander risks' during pandemics and infectious diseases and contract tracing during ebola.
The Janssen COVID‑19 vaccine, (Ad26.COV2.S) sold under the brand name Jcovden, is a COVID‑19 vaccine that was developed by Janssen Vaccines in Leiden, Netherlands, and its Belgian parent company Janssen Pharmaceuticals, a subsidiary of American company Johnson & Johnson.