U.S. Route 19 or U.S. Highway 19 (US 19) is a north–south United States Numbered Highway in the Eastern United States. Despite encroaching Interstate Highways, the route has remained a long-haul road, connecting the Gulf of Mexico with Lake Erie.
State Route 168 is a state highway in Knox County, Tennessee, that is 18.1 miles long. Its western terminus is with US 129/SR 115, and its eastern terminus is with US 11/US 11E/US 11W/US 70/SR 1.
U.S. Route 11W (US 11W), locally known as Bloody 11W, is a divided highway of US 11 in the U.S. states of Tennessee and Virginia. The United States Numbered Highway, which is complemented by US 11E to the south and east, runs 110.28 miles (177.48 km) from US 11, US 11E, and US 70 in Knoxville, Tennessee, north and east to US 11, US 11E, US 19, and US 421 in Bristol, Virginia. US 11W connects Knoxville and the twin cities of Bristol, Virginia, and Bristol, Tennessee, with the East Tennessee communities of Rogersville and Kingsport. The U.S. Highway has an unsigned concurrency with State Route 1 (SR 1) for its whole length in Tennessee. In 2021, the route in its entirety was labeled among the top 25 deadliest highways in the U.S.
U.S. Route 11E (US 11E) is a divided highway of US 11 in the U.S. states of Tennessee and Virginia. The United States Numbered Highway, which is complemented by US 11W to the north and west, runs 120.94 miles (194.63 km) from US 11, US 11W, and US 70 in Knoxville, Tennessee, north and east to US 11, US 11W, US 19, and US 421 in Bristol, Virginia. US 11E connects Knoxville and the twin cities of Bristol, Virginia, and Bristol, Tennessee, with the East Tennessee communities of Morristown, Greeneville, and Johnson City. The U.S. Highway runs concurrently with US 70 and US 25W east of Knoxville, US 321 from Greeneville and Johnson City, and both US 19W and US 19 between Johnson City and Bristol. US 11E also has an unsigned concurrency with State Route 34 (SR 34) for almost all of its course in Tennessee.
U.S. Route 11 (US 11) is a north–south United States Numbered Highway in western Virginia. At 339 miles (546 km), it is the second longest numbered route and longest primarily north–south route in the state. It enters the state from Tennessee as the divided routes US 11E and US 11W at Bristol, roughly follows the West Virginia border through the Blue Ridge Mountains and Shenandoah Valley, and enters the Eastern Panhandle of West Virginia from Frederick County. Most of the route closely parallels I-81. From south to north, US 11 serves the cities and towns of Bristol, Abingdon, Wytheville, Christiansburg, Roanoke, Lexington, Staunton, Harrisonburg, Strasburg, and Winchester. As one of the original U.S. Highways, it was first designated through Virginia in 1926 and has largely followed the same route since. Prior to the construction of the Interstate Highway System, it was the primary long-distance route for traversing the western part of the state. Much of it roughly follows the Great Wagon Road, a colonial-era road that followed the Appalachian Mountains from Georgia to Pennsylvania.
U.S. Route 421 (US 421) is a part of the U.S. Highway System that runs from Fort Fisher, North Carolina to Michigan City, Indiana. In Virginia, the U.S. Highway runs 69.23 miles (111.41 km) from the Tennessee state line between the twin cities of Bristol, Tennessee and Bristol, Virginia north and west to the Kentucky state line near St. Charles. Between its endpoints, US 421 has lengthy concurrencies with US 23 and US 58 during its course through Bristol, Weber City, Gate City, Duffield, and Pennington Gap in Southwest Virginia.
U.S. Route 19 (US 19) is a part of the United States Numbered Highway System that runs from Memphis, Florida, to Erie, Pennsylvania. In Virginia, the highway runs 88.89 miles (143.05 km) between two pairs of twin cities: Bristol, Tennessee, and Bristol, Virginia, at the Virginia–Tennessee state line, and Bluefield, Virginia, and Bluefield, West Virginia, at the Virginia–West Virginia state line. Between its endpoints, US 19 has lengthy concurrencies with US 11, US 58 Alternate, and US 460 during its course connecting Abingdon, Lebanon, and Tazewell within Washington, Russell, and Tazewell counties in Southwest Virginia.
State Route 66 is a state-maintained highway in eastern Tennessee, including a six-lane divided highway known as Winfield Dunn Parkway in Sevier County, a four-lane expressway in Hamblen and Jefferson counties and a two-lane rural collector through mountainous terrain continuing to the northeast terminus in Hancock County.
State Route 5 is a 120-mile-long (190 km) north–south state highway in the western part of the U.S. state of Tennessee. Except for the section northwest of Union City, it is entirely concurrent with U.S. Route 45 and US 45W.
State Route 67 is a state-maintained highway in northeastern Tennessee, including a four-lane divided highway segments in both Washington County and Carter County, and part of a significant two-lane segment passing over the Butler Bridge some 80 feet (24 m) above the TVA Watauga Reservoir near Butler in Johnson County, Tennessee.
U.S. Route 19 (US 19) traverses approximately 11.8 miles (19.0 km) across the Tri-Cities area of East Tennessee. The highway begins at Bluff City, where the highway splits into US 19E and US 19W, which both head into North Carolina and rejoin to form US 19 in North Carolina. US 19's Tennessee portion ends at the Virginia state line at the twin cities of Bristol, Tennessee, and Bristol, Virginia.
State Route 70 is a state-maintained highway in East Tennessee, beginning at the border with North Carolina in the midst of the Cherokee National Forest and the Great Smoky Mountains and ending at the Virginia border in the extremely rural and mountainous terrain of Hancock County.
U.S. Route 421 is a north–south United States highway that runs for 43.4 miles (69.8 km) in East Tennessee, connecting the cities of Mountain City and Bristol.
State Route 75 is state highway in Tennessee in the northeastern portion of the state. The highway begins at US 11E and US 321 in Limestone and ends at SR 126 in Blountville.
State Route 36 (SR 36) is a 28.6-mile-long (46.0 km) state highway, broken in two segments. In Unicoi County, it serves as the hidden concurrency of U.S. Route 19W; in Washington and Sullivan counties, it serves as a stand-alone secondary road connecting the cities of Johnson City and Kingsport.
State Route 394 is a west-east state highway in Sullivan County, Tennessee. It serves as southern bypass of Bristol and as a connector route from Interstate 81 (I-81) to Bristol Motor Speedway. The western terminus is at an intersection with U.S. Route 11W northwest of Blountville and the eastern terminus is at a junction with US 421 southeast of Bristol. The route heads southeast and crosses I-81 before passing through Blountville. From here, SR 394 continues southeast to an interchange with US 11E/US 19 near Bristol Motor Speedway, where it turns northeast and continues to US 421.
State Route 32 is a state highway in East Tennessee. For most of its route, it is an unsigned companion route concurrent with U.S. Route 25E. The highway stretches 89 miles from the North Carolina state line to the Tennessee-Kentucky state line near the town of Cumberland Gap.
State Route 126 is a 24.6-mile-long (39.6 km) state highway that travels through Sullivan County in East Tennessee. It connects Kingsport and Bristol.
State Route 91 is a state highway in the northeastern portion of the U.S. state of Tennessee, in the area known as the Tri-Cities region. The route connects Johnson City with Damascus, Virginia via Elizabethton, Hunter, and Mountain City.
State Route 34 is a state highway located in East Tennessee. The 155.7-mile-long (250.6 km) route traverses several cities through eight counties from the Knoxville area to the North Carolina state line via Greeneville and Bristol. The portion from Carter to Bristol is concurrent with U.S. Route 11E (US 11E) while the portion from Bristol to North Carolina is concurrent with US 421.
US 11E / US 19W / SR 34 in Bluff City 
SR 75 near Abingdon, VA 
