Henrietta Lacks was an African-American woman whose cancer cells are the source of the HeLa cell line, the first immortalized human cell line and one of the most important cell lines in medical research. An immortalized cell line reproduces indefinitely under specific conditions, and the HeLa cell line continues to be a source of invaluable medical data to the present day.
HeLa is an immortalized cell line used in scientific research. It is the oldest human cell line and one of the most commonly used. HeLa cells are durable and prolific, allowing for extensive applications in scientific study. The line is derived from cervical cancer cells taken on February 8, 1951, from Henrietta Lacks, a 31-year-old African American mother of five, after whom the line is named. Lacks died of cancer on October 4, 1951.
Courtney Bernard Vance is an American actor. He started his career on stage before moving to film and television. Vance has received various accolades, including a Tony Award and two Primetime Emmy Awards, as well as nominations for a Grammy Award, Golden Globe Award, and Screen Actors Guild Award.
Renée Elise Goldsberry is an American actress and singer. Known for her roles on stage and screen she has received a Tony Award, a Drama Desk Award, and a Grammy Award as well as a nomination for a Primetime Emmy Award.
Harpo Productions is an American multimedia production company founded by Oprah Winfrey and based in West Hollywood, California. The name "Harpo" is "Oprah" spelled backwards and it was also the name of her on-screen husband in the film The Color Purple (1985).
Adriane Lenox is an American actress, best known for her performances in Broadway theatre. Her performance in the play Doubt: A Parable garnered her the Tony Award for Best Featured Actress in a Play in 2005. She received another Tony Award nomination for After Midnight in 2014.
George Otto Gey was the cell biologist at Johns Hopkins Hospital who is credited with propagating the HeLa cell line from Henrietta Lacks' cervical tumor. He spent over 35 years developing numerous scientific breakthroughs under the Johns Hopkins Medical School and Hospital.
Rebecca L. Skloot is an American science writer who specializes in science and medicine. Her first book, The Immortal Life of Henrietta Lacks (2010), was one of the best-selling new books of 2010, staying on The New York Times Bestseller list for over 6 years and eventually reaching #1. It was adapted into a movie by George C. Wolfe, which premiered on HBO on April 22, 2017, and starred Rose Byrne as Skloot, and Oprah Winfrey as Lacks's daughter Deborah.
Merle Dandridge is an American actress and singer. She is best known for performing in Broadway musicals such as Jesus Christ Superstar, Spamalot, Rent, and Once on This Island, as well as her video game roles as Alyx Vance in Half-Life 2 and Marlene in The Last of Us franchise. She played the leading role of Grace Greenleaf in the Oprah Winfrey Network drama series, Greenleaf (2016–2020). She's had recurring roles on television series such as Sons of Anarchy and The Night Shift and starred as Kim Hammond in the first season of HBO Max comedy-drama series The Flight Attendant in 2020. In 2022, Dandridge began starring as Natasha Seo-Yeon Ross in the ABC action series Station 19. She reprised her role as Marlene in the 2023 television adaptation of The Last of Us.
The Oprah Winfrey Network (OWN) is an American multinational basic cable television network which launched on January 1, 2011, effectively replacing the Discovery Health Channel. OWN is a joint venture between Warner Bros. Discovery and Harpo Studios, conceptualized largely by popular talk show host, Oprah Winfrey—the name of Harpo Studios is Winfrey’s first name, spelled backwards.
Oprah Gail Winfrey, known mononymously as Oprah, is an American talk show host, television producer, actress, author, and media proprietor. She is best known for her talk show, The Oprah Winfrey Show, broadcast from Chicago, which ran in national syndication for 25 years, from 1986 to 2011. Dubbed the "Queen of All Media", she was the richest African-American of the 20th century and was once the world's only black billionaire. By 2007, she was often ranked as the most influential woman in the world.
The Immortal Life of Henrietta Lacks (2010) is a non-fiction book by American author Rebecca Skloot. It was the 2011 winner of the National Academies Communication Award for best creative work that helps the public understanding of topics in science, engineering or medicine.
An immortalised cell line is a population of cells from a multicellular organism that would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division. The cells can therefore be grown for prolonged periods in vitro. The mutations required for immortality can occur naturally or be intentionally induced for experimental purposes. Immortal cell lines are a very important tool for research into the biochemistry and cell biology of multicellular organisms. Immortalised cell lines have also found uses in biotechnology.
Lydia Dean Pilcher is an American film and television producer and director and founder of Cine Mosaic, a production company based in New York City.
Omar Dorsey is an American actor. He has appeared in films The Blind Side (2009), Django Unchained (2012), and Selma (2014) playing James Orange. In 2016, Dorsey began starring as Hollingsworth "Hollywood" Desonier in the Oprah Winfrey Network drama series Queen Sugar.
A Wrinkle in Time is a 2018 American science fantasy adventure film directed by Ava DuVernay and written by Jennifer Lee and Jeff Stockwell, based on Madeleine L'Engle's 1962 novel of the same name. Produced by Walt Disney Pictures and Whitaker Entertainment, the story follows a young girl who, with the help of three astral travelers, sets off on a quest to find her missing father. The film stars Oprah Winfrey, Reese Witherspoon, Mindy Kaling, Levi Miller, Storm Reid, Gugu Mbatha-Raw, Michael Peña, Zach Galifianakis, and Chris Pine.
Chester Milton Southam was an immunologist and oncologist at Memorial Sloan Kettering Cancer Center and Cornell University Medical College; he went to Thomas Jefferson University in 1971 and worked there until the end of his career. He ran many experiments involving the injection of live cancer cells into human subjects, without disclosing that they were cancer cells, and using subjects with questionable ability to consent, such as incarcerated people and senile patients in long-term care at a hospital. The New York State Attorney General encouraged the Board of Regents of the University of the State of New York to take away Southam's medical license. Regardless, he went on to be president of the American Association for Cancer Research. His work was labeled by both modern scientists and his contemporaries as highly dangerous and unethical.
Greenleaf is an American drama television series created by Craig Wright, and executive produced by Oprah Winfrey and Lionsgate Television. Clement Virgo also serves as an executive producer and director. It stars Keith David, Lynn Whitfield, and Merle Dandridge. Greenleaf premiered on the Oprah Winfrey Network (OWN) on June 21, 2016.
Deborah Joy Imani Winans is an American actress and singer, and member of the musical Winans family. She starred as Charity Greenleaf-Satterlee in the Oprah Winfrey Network drama series, Greenleaf.
On the Record is a 2020 American documentary film directed by Kirby Dick and Amy Ziering. It centers on allegations of sexual abuse and harassment against hip-hop mogul Russell Simmons. Executive producer Oprah Winfrey publicly withdrew from the film shortly before it was released, citing "creative differences", severing a production deal with Apple TV+. The film premiered at Sundance on January 25, 2020, and was acquired by HBO Max, which released it digitally on May 27, 2020.
