Tim Clausen | |
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Born | Tim Clausen 12 March 1969 |
Alma mater | |
Awards |
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Scientific career | |
Fields | structural biology, protein folding |
Institutions | |
Thesis | (1997) |
Doctoral advisor | Robert Huber |
Website | clausen |
Tim Clausen (born 12 March 1969) is a structural biologist [1] and a senior scientist at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria. [2]
Tim Clausen was born in Flensburg, West Germany, in 1969. He did his undergraduate studies in biology at the University of Konstanz from 1988. He graduated with a diploma following research at the lab of Sandro Ghisla in 1994. Following his graduation, Clausen joined the lab of Robert Huber at the Max Planck Institute of Biochemistry in Martinsried for his PhD studies. Clausen obtained his PhD in chemistry summa cum laude in 1997.
In 1997, Tim Clausen became a postdoctoral researcher with Albrecht Messerschmidt at the Max Planck Institute of Biochemistry, leading from 1999 on a small group studying pyridoxal phosphate enzymes. He obtained a lecture qualification (Habilitation) in biochemistry by the University of Konstanz in 2001. [3]
In 2002, Tim Clausen became a group leader in structural biology at the Research Institute of Molecular Pathology (IMP) in Vienna. In 2009, he was promoted to senior scientist. [4]
Tim Clausen studies the protein quality control system that cells evolved, and through which molecular chaperones and proteases monitor the functionality of each protein, thereby reducing the amount of misfolded molecules that may undergo dangerous interactions. Tim Clausen and his lab perform structure-function analyses of several eukaryotic and prokaryotic quality control factors to find novel strategies to combat protein-folding diseases and bacterial pathogenicity. [2]
Tim Clausen was awarded a Max Planck Fellowship in 1994; the Heinz Mayer-Leibnitz Award of the Deutsche Forschungsgemeinschaft in 2004; [5] he was selected EMBO young investigator in 2005 and elected European Molecular Biology Organization EMBO member in 2010. [6] He was awarded a European Research Council (ERC) advanced grant in 2016. [7]
The Gottfried Wilhelm Leibniz Prize, in short Leibniz Prize, is awarded by the German Research Foundation to "exceptional scientists and academics for their outstanding achievements in the field of research". Since 1986, up to ten prizes are awarded annually to individuals or research groups working at a research institution in Germany or at a German research institution abroad. It is considered the most important research award in Germany.
Franz-Ulrich Hartl is a German biochemist and Managing Director of the Max Planck Institute of Biochemistry. He is known for his pioneering work in the field of protein-mediated protein folding and is a recipient of the 2011 Lasker Award along with Arthur L. Horwich.
The Heinz Maier-Leibnitz-Preis, in honor and memory of the German physicist Heinz Maier-Leibnitz, is funded by the Bundesministerium für Bildung und Forschung, and it is awarded by a selection committee appointed by the Deutsche Forschungsgemeinschaft and the BMBF. Since 2013, there are ten recipients of the prize and each receives 20,000 Euros, which is an increase over the original 16,000 Euros that had been given to six recipients per year until 2012.
Heinz Maier-Leibnitz was a German physicist. He made contributions to nuclear spectroscopy, coincidence measurement techniques, radioactive tracers for biochemistry and medicine, and neutron optics. He was an influential educator and an advisor to the Federal Republic of Germany on nuclear programs.
The Research Institute of Molecular Pathology (IMP) is a biomedical research center, which conducts curiosity-driven basic research in the molecular life sciences.
Dietmar Vestweber is a biochemist and cell biologist. He is the founding director of the Max Planck Institute for Molecular Biomedicine in Münster, Germany.
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Jörg Vogel is a German scientist in the field of RNA biology and microbiology. He holds a position as full professor, chairs the Institute for Molecular Infection Biology (IMIB) at the University of Würzburg, Germany, and is a founding Helmholtz-Institute director. Vogel studied biochemistry at the Humboldt University of Berlin and the Imperial College London. After his PhD work (1996–1999) he performed postdoctoral research at the Uppsala University, Sweden and was an EMBO fellow at the Hebrew University Jerusalem, Israel. From 2004 to 2009 he was a group leader at the Max Planck Institute for Infection Biology. Since 2009 he is a full professor at the IMIB and head of the institute as successor to Jörg Hacker. Furthermore, he is founding director of the Helmholtz-Institute for RNA-based Infection Research (HIRI) in Würzburg that was established in 2017.
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Andreas Plückthun is a scientist whose research is focused on the field of protein engineering. Andreas Plückthun is the director of the department of biochemistry at the University of Zurich. Plückthun was appointed to the faculty of the University of Zurich as a Full professor of biochemistry in 1993. Plückthun was group leader at the Max Planck Institute of Biochemistry, Germany (1985-1993). He was elected to the European Molecular Biology Organization (EMBO) in 1992, and named a member of the German National Academy of Science (Leopoldina) in 2003. He is cofounder of the biotechnology companies Morphosys Molecular Partners AG and G7 Therapeutics..
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Jan-Michael Peters is a cell- and molecular biologist. Since 2013, he is Scientific Director of the Research Institute of Molecular Pathology (IMP) in Vienna.
Alexander Stark is a biochemist and computational biologist working on the regulation of gene expression in development. He is a senior scientist at the Research Institute of Molecular Pathology (IMP) at the Vienna Biocenter and adjunct professor of the Medical University of Vienna.
Elena Conti is an Italian biochemist and molecular biologist. She serves as Director and Scientific Member of the Max Planck Institute of Biochemistry in Martinsried, Germany, where she uses structural biology and biophysical techniques to study RNA transport and RNA metabolism. Together with Elisa Izaurralde, she helped characterize proteins important for exporting mRNA out of the nucleus.
Elisa Izaurralde was an Uruguayan biochemist and molecular biologist. She served as Director and Scientific Member of the Department of Biochemistry at the Max Planck Institute for Developmental Biology in Tübingen from 2005 until her death in 2018. In 2008, she was awarded the Gottfried Wilhelm Leibniz Prize, shared with Elena Conti, for "fundamental new insights into intracellular RNA transport and RNA metabolism". Together with Conti, she helped characterize proteins important for exporting mRNA out of the nucleus and later in her career she helped elucidate mechanisms of mRNA silencing, translational repression, and mRNA decay.
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Andrea Pauli is a developmental biologist and biochemist studying how the egg transitions into an embryo, and more specifically the molecular mechanisms underlying vertebrate fertilisations, egg dormancy, and subsequent egg activation. Her lab uses zebrafish as the main model organism. Andrea Pauli is a group leader at the Research Institute of Molecular Pathology (IMP) at the Vienna Biocenter in Austria.