Tripartite motif containing 34

TRIM34
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2EGP
Identifiers
Aliases	TRIM34 , IFP1, RNF21, tripartite motif containing 34
External IDs	OMIM: 605684 HomoloGene: 136478 GeneCards: TRIM34
Gene location (Human)
Chr.	Chromosome 11 (human)
End	5,644,398 bp
RNA expression pattern
	Top expressed in
	monocyte; ; lymph node; ; blood; ; spleen; ; placenta; ; appendix; ; right adrenal gland; ; rectum; ; left adrenal gland; ; right uterine tube;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	zinc ion binding ; metal ion binding ; molecular function ;
Cellular component	cytoplasm ; cytosol ; intracellular anatomical structure ;
Biological process	protein trimerization ; positive regulation of DNA-binding transcription factor activity ; defense response to virus ; interferon-gamma-mediated signaling pathway ;
	Sources:Amigo / QuickGO
Orthologs
	53840
	n/a
	ENSG00000258659
	n/a
	Q9BYJ4
	n/a
	NM_130390 ; NM_001003827 ; NM_021616 ; NM_130389
	n/a
	NP_001003827 ; NP_067629 ; NP_569074
	n/a
	Wikidata
View/Edit Human

Last updated October 01, 2023

Tripartite motif containing 34 is a protein that, in humans, is encoded by the TRIM34 gene.^[3]

Function

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. Expression of this gene is up-regulated by interferon. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from the upstream TRIM6 gene has also been observed, which results in a fusion product from these neighboring family members.

Related Research Articles

Tripartite motif-containing protein 21, also known as E3 ubiquitin-protein ligase TRIM21, is a protein that in humans is encoded by the TRIM21 gene. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. It is expressed in most human tissues.

Tripartite motif-containing 24 (TRIM24) also known as transcriptional intermediary factor 1α (TIF1α) is a protein that, in humans, is encoded by the TRIM24 gene.

Zinc finger protein RFP is a protein that in humans is encoded by the TRIM27 gene.

Tripartite motif-containing protein 37 is an E3 ubiquitin ligase in humans that is encoded by the TRIM37 gene.

Tripartite motif-containing protein 25 is a protein that in humans is encoded by the TRIM25 gene.

Collagen alpha-1(XIII) chain is a protein that in humans is encoded by the COL13A1 gene.

Midline-2 is a protein that in humans is encoded by the MID2 gene.

Tripartite motif-containing protein 32 is a protein that in humans is encoded by the TRIM32 gene. Since its discovery in 1995, TRIM32 has been shown to be implicated in a number of diverse biological pathways.

GTP-binding protein ARD-1 is a protein that in humans is encoded by the TRIM23 gene.

Tripartite motif-containing 22, also known as TRIM22, is a protein which in humans is encoded by the TRIM22 gene.

Tripartite motif-containing protein 31 is a protein that in humans is encoded by the TRIM31 gene.

E3 ubiquitin-protein ligase TRIM33, also known as (ectodermin homolog and tripartite motif-containing 33) is a protein encoded in the human by the gene TRIM33, a member of the tripartite motif family.

Tripartite motif-containing protein 3 is a protein that in humans is encoded by the TRIM3 gene.

Tripartite motif-containing protein 16 is a protein that in humans is encoded by the TRIM16 gene.

Tripartite motif-containing protein 9 is a protein that in humans is encoded by the TRIM9 gene.

Tripartite motif-containing protein 6 is a protein that in humans is encoded by the TRIM6 gene.

Tripartite motif-containing protein 11 is a protein found in humans that is encoded by the TRIM11 gene.

Tripartite motif-containing protein 15 is a protein that in humans is encoded by the TRIM15 gene.

Tripartite motif containing 69 is a protein that in humans is encoded by the TRIM69 gene.

Tripartite motif containing 38 is a protein that in humans is encoded by the TRIM38 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000258659 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Tripartite motif containing 34" . Retrieved 2016-09-01.

Tripartite motif containing 34

Contents

Function

Related Research Articles

References

Further reading