USP37

USP37
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3U12
Identifiers
Aliases	USP37 , ubiquitin specific peptidase 37
External IDs	MGI: 2442483 HomoloGene: 10858 GeneCards: USP37
Gene location (Human)
Chr.	Chromosome 2 (human)
End	218,568,351 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	74,583,443 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; Achilles tendon; ; sperm; ; corpus callosum; ; thymus; ; palpebral conjunctiva; ; bone marrow cells; ; testicle; ; thymus; ; visceral pleura;
	Top expressed in
	spermatocyte; ; spermatid; ; hand; ; secondary oocyte; ; otolith organ; ; utricle; ; morula; ; ureter; ; primitive streak; ; foot;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase activity ; cysteine-type endopeptidase activity ; cysteine-type peptidase activity ; protein binding ; protein kinase binding ; hydrolase activity ; thiol-dependent deubiquitinase ;
Cellular component	nucleus ; nucleoplasm ;
Biological process	cell cycle ; protein K48-linked deubiquitination ; ubiquitin-dependent protein catabolic process ; protein K11-linked deubiquitination ; proteolysis ; cell division ; regulation of DNA replication ; protein deubiquitination ; G1/S transition of mitotic cell cycle ;
	Sources:Amigo / QuickGO
Orthologs
	57695
	319651
	ENSG00000135913
	ENSMUSG00000033364
	Q86T82
	Q8C0R0
	NM_020935
	NM_176972 ; NM_001310662
	NP_065986
	NP_001297591 ; NP_795946
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Ubiquitin specific processing protease 37 is an enzyme that in humans, is encoded by the USP37 gene.^[5]^[6]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000135913 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033364 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346. S2CID 2856065.
↑ "Entrez Gene: USP37 ubiquitin specific peptidase 37".

Nagase T, Kikuno R, Nakayama M, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (4): 273–81. doi: 10.1093/dnares/7.4.271 . PMID 10997877.
Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732 . PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Quesada V, Díaz-Perales A, Gutiérrez-Fernández A, et al. (2004). "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases". Biochem. Biophys. Res. Commun. 314 (1): 54–62. doi:10.1016/j.bbrc.2003.12.050. PMID 14715245.
Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. doi: 10.1016/j.cub.2004.07.051 . PMID 15324660. S2CID 2371325.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID 17081983. S2CID 7827573.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000135913 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033364 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12838346-5] Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346. S2CID 2856065.

[entrez-6] "Entrez Gene: USP37 ubiquitin specific peptidase 37".

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USP37

Related Research Articles

References

Further reading