USP44

USP44
Identifiers
Aliases	USP44 , ubiquitin specific peptidase 44
External IDs	OMIM: 610993; MGI: 3045318; HomoloGene: 12961; GeneCards: USP44; OMA:USP44 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q22 Start 95,516,560 bp [1] End 95,551,476 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 C2 Start 93,667,417 bp [2] End 93,693,950 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte sperm testicle left testis right testis buccal mucosa cell lower lobe of lung cerebellar hemisphere tibial nerve right hemisphere of cerebellum Top expressed in spermatid seminiferous tubule spermatocyte epiblast tail of embryo embryo embryo ventricular zone primitive streak thymus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function zinc ion binding peptidase activity cysteine-type peptidase activity protein binding hydrolase activity metal ion binding thiol-dependent deubiquitinase Cellular component nucleus nucleoplasm cytoplasm Biological process cell cycle regulation of mitotic cell cycle spindle assembly checkpoint ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process proteolysis cell division negative regulation of ubiquitin protein ligase activity protein deubiquitination chromosome segregation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84101 327799 Ensembl ENSG00000136014 ENSMUSG00000020020 UniProt Q9H0E7 Q8C2S0 RefSeq (mRNA) NM_001042403 NM_001278393 NM_032147 NM_001347936 NM_001347937 NM_001206851 NM_183199 NM_001376981 NM_001400981 RefSeq (protein) NP_001035862 NP_001265322 NP_115523 NP_001334865 NP_001334866 NP_001193780 NP_001363910 NP_001387910 Location (UCSC) Chr 12: 95.52 – 95.55 Mb Chr 10: 93.67 – 93.69 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase 44 is an enzyme that in humans is encoded by the USP44 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000136014 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000020020 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID   12838346. S2CID   2856065.
6. "Entrez Gene: USP44 ubiquitin specific peptidase 44".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Quesada V, Díaz-Perales A, Gutiérrez-Fernández A, et al. (2004). "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases". Biochem. Biophys. Res. Commun. 314 (1): 54–62. doi:10.1016/j.bbrc.2003.12.050. PMID   14715245.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Stegmeier F, Rape M, Draviam VM, et al. (2007). "Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities". Nature. 446 (7138): 876–81. Bibcode:2007Natur.446..876S. doi:10.1038/nature05694. PMID   17443180. S2CID   4321083.