Ultra-processed food

Last updated

Bowl of Froot Loops cereal, an ultra-processed cereal Froot-Loops-Cereal-Bowl.jpg
Bowl of Froot Loops cereal, an ultra-processed cereal
Aisle of ultra-processed foods in an American supermarket Walmart Wenatchee.jpg
Aisle of ultra-processed foods in an American supermarket

An ultra-processed food (UPF) is an industrially formulated edible substance derived from natural food or synthesized from other organic compounds. [1] [2] The resulting products are designed to be highly profitable, convenient, and hyperpalatable, often through food additives such as preservatives, colourings, and flavourings. [3] UPFs have often undergone processes such as moulding/extruding, hydrogenation or frying. [4]

Contents

Ultra-processed foods first became ubiquitous in the 1980s, [5] though the term "ultra-processed food" gained prominence from a 2009 paper by Brazilian researchers as part of the Nova classification system. [6] In the Nova system, UPFs include most bread and other massed-produced baked goods, frozen pizza, instant noodles, flavored yogurt, fruit and milk drinks, “diet” products, baby food, and most of what is considered junk food. [7] [8] The Nova definition considers ingredients, processing, and how products are marketed; [9] nutritional content is not evaluated. [10] As of 2024, research into the effects of UPFs is rapidly evolving. [11] [4]

Since the 1990s, UPF sales have been increasing or remained high in most countries. In the limited available national data, as of 2023, consumption is highest in the United States (58% of daily calories) and United Kingdom (57%), and ranges widely, with Chile, France, Mexico and Spain among the countries in the 25-35% range, and Colombia, Italy, and Taiwan among those at or below 20%. [4]

Epidemiological data suggest that consumption of ultra-processed foods is associated with non-communicable diseases and obesity. [12] A 2024 meta analysis published in The BMJ , identified 32 studies that associated UPF with negative health outcomes, though the specific mechanism of the effects was not clear. [11]

Some authors have criticised the concept of "ultra-processed foods" as poorly defined, and the Nova classification system as too focused on the type rather than the amount of food consumed. [13] Other authors, mostly in the field of nutrition, have been critical of the lack of attributed mechanisms for the health effects, focusing on how the current research evidence does not provide specific explanations for how ultra-processed food affects body systems. [14]

Definitions

Concerns about food processing have existed since at least the Industrial Revolution. [15] The origin of ultra-processed food is more recent: Michael Pollan's influential book The Omnivore's Dilemma (2006) referred to highly processed industrial food as 'edible food-like substances'. [16] Carlos Augusto Monteiro cited Pollan as an influence in coining the term 'ultra-processed food' in a 2009 commentary. [9] Some sources have described UPF as "predigested food". [17] [18] [19] [20]

Monteiro's team developed the Nova classification for grouping unprocessed and processed foods beginning in 2010, whose definition of ultra-processing became the most widely accepted, refined through successive publications. [7] The identification of ultra-processed foods, as well as the category itself, is a subject of debate among nutrition and public health scientists, and other definitions have been proposed. [21]

A survey of systems for classifying levels of food processing in 2021 identified four 'defining themes':

Monteiro's 2009 commentary

Carlos Monteiro, working with a team of researchers at the University of São Paulo, first published the concept of ultra-processed foods:

Ultra-processed foods are basically confections of group 2 ingredients [substances extracted from whole foods], typically combined with sophisticated use of additives, to make them edible, palatable, and habit-forming. They have no real resemblance to group 1 foods [minimally processed foods], although they may be shaped, labelled and marketed so as to seem wholesome and 'fresh'. Unlike the ingredients included in group 2, ultra-processed foods are typically not consumed with or as part of minimally processed foods, dishes and meals. On the contrary, they are designed to be ready-to-eat (sometimes with addition of liquid such as milk) or ready-to-heat, and are often consumed alone or in combination (such as savoury snacks with soft drinks, bread with burgers). [9]

This definition is as much social as one based on specific ingredients, which makes the understanding of ultra-processed foods highly intuitive, even among untrained consumers. [23] [24] A letter responding to Monteiro's 2009 commentary suggested that the definition 'lacks precision', since it lacks the measurable definitions of traditional food science. [25] Because of this, researchers disagree whether the definition can form a valid basis for scientific control. [13] Researchers have developed a quantitative definition for hyperpalatable food, but not for ultra-processed food. [26]

Nova classification

Label for Nova group 4, 'ultra-processed foods' NOVA group 4.svg
Label for Nova group 4, 'ultra-processed foods'

Monteiro's team subsequently presented ultra-processed foods as a group in the Nova food classification system. [6] The system focuses on food processing rather than foods types or nutrients. Nova categorizes foods into four groups: [3] unprocessed or minimally processed foods, processed ingredients, processed foods, and ultra-processed foods.

Nova is an open classification that refines its definitions gradually through scientific publications rather than through a central advisory board. [7] The most recent overview of Nova defines ultra-processed food as:

Industrially manufactured food products made up of several ingredients (formulations) including sugar, oils, fats and salt (generally in combination and in higher amounts than in processed foods) and food substances of no or rare culinary use (such as high-fructose corn syrup, hydrogenated oils, modified starches and protein isolates). Group 1 [un- or minimally processed] foods are absent or represent a small proportion of the ingredients in the formulation. Processes enabling the manufacture of ultra-processed foods include industrial techniques such as extrusion, moulding and pre-frying; application of additives including those whose function is to make the final product palatable or hyperpalatable such as flavours, colourants, non-sugar sweeteners and emulsifiers; and sophisticated packaging, usually with synthetic materials. Processes and ingredients here are designed to create highly profitable (low-cost ingredients, long shelf-life, emphatic branding), convenient (ready-to-(h)eat or to drink), tasteful alternatives to all other Nova food groups and to freshly prepared dishes and meals.

Ultra-processed foods are further defined as measurably distinguishable from processed foods by ingredients "of no culinary use (varieties of sugars such as fructose, high-fructose corn syrup, 'fruit juice concentrates', invert sugar, maltodextrin, dextrose and lactose; modified starches; modified oils such as hydrogenated or interesterified oils; and protein sources such as hydrolysed proteins, soya protein isolate, gluten, casein, whey protein and 'mechanically separated meat') or of additives with cosmetic functions (flavours, flavour enhancers, colours, emulsifiers, emulsifying salts, sweeteners, thickeners and anti-foaming, bulking, carbonating, foaming, gelling and glazing agents) in their list of ingredients." [27]

The Nova definition of ultra-processed food does not comment on the nutritional content of food and is not intended to be used for nutrient profiling. [10]

International Agency for Research on Cancer (IARC)

The International Agency for Research on Cancer, an intergovernmental agency that forms part of the World Health Organization, classifies foods by their degree of processing. This system breaks food into 'non-processed', 'moderately processed', and 'highly processed' food. [28] [ clarification needed ] The system does not take into account the nature or purpose of changes. [29]

Siga Index

The Siga Index is a classification system for processed foods developed in France. [5] It is based on the degree of processing and the nutritional quality of foods, using a holistic and reductionist approach. [30]

The Siga Index assigns a score from 1 to 100 to each food product, where higher scores indicate higher nutritional quality and lower processing. The Siga Index also defines ultra-processed foods (UPFs) as those with a score below 40, which are considered to have low nutritional value and high levels of additives, preservatives, and artificial ingredients. [31]

International Food Information Council (IFIC)

The International Food Information Council defines five levels of food processing: minimally processed, foods processed for preservation, mixtures of combined ingredients, ready-to-eat processed foods, and prepared foods/meals. [32] [33]

NUPENS

The Center for Epidemiological Research in Nutrition and Health at the University of São Paulo has proposed a variant on the Nova classification consisting of: unprocessed, minimally, or moderately processed foods; processed foods; and ultra-processed foods. [34]

Economics

The high amount of processing lends ultra-processed food to be subject to different economic constraints compared to natural food.

Profitability

Nestle is one of the world's major distributors of ultra-processed food, with a presence in 188 countries. Nestle Israel ice cream delivery truck.jpg
Nestlé is one of the world's major distributors of ultra-processed food, with a presence in 188 countries.

Ultra-processed foods often use less expensive ingredients, allowing ultra-processed food to be priced lower. [35] Furthermore, ultra-processed foods are more consistently available in stores. [36] [37] Global production networks of multinational food companies creating ultra-processed food are supported by high brand awareness, aggressive globalization tactics, and the purchasing of local companies selling similar products. [38]

Companies selling ultra-processed food frequently target youth consumers and middle income countries. [36] [39] Many of these companies use big data to choose which consumers to market to. [40] Furthermore, the ultra-processed food industry uses indirect and direct lobbying in large countries to influence local food policy. [41] [42]

Affordability for consumers

Ultra-processed food as a percentage of household purchases in some European countries, as of 2018 Ultra-processed food as a %25 of household purchases (en).svg
Ultra-processed food as a percentage of household purchases in some European countries, as of 2018

They often have an extended shelf life, an important consideration for lower income consumers without reliable access to refrigeration. Among other reasons for the popularity of ultra-processed foods are the inexpensive cost of their main ingredients. The price of ultra-processed food fluctuated less than unprocessed food over a twelve-year period. [35]

Health effects

The effect of ultra-processed foods on health has mainly been investigated using nutritional epidemiology and so far there has been no randomized controlled trial to investigate the effect of these foods on any health outcome other than weight gain. These studies have shown an overall increased risk for disease, [12] [43] although studies separating different types of ultra-processed food have found adverse effects mainly for only some sub-groups such as soft drinks. [44] Overall, there is an association between certain poor health outcomes including poor cardiometabolic and mental health, and reduced life expectancy and consumption of UPF. [11] One study proposed that food addiction may also be associated with consumption of ultra-processed foods. [45]

One possible explanation for the adverse effect on health are the high amounts of sugar, fat and salt in these foods, although that does not apply to all ultra-processed foods. Other potential explanations are the presence of contaminants, certain food additives, and the high heat treatment of these foods. [46] There is currently however no scientific consensus. [47]

The publicizing of these findings has sparked debate over the categoric demonization of ultra-processed foods, with some critics calling for a more balanced view, and others arguing that promoting UPFs could undermine public health communication about their risks. [10] [48] [49] [50] [51] Jessica Wilson, a registered dietitian in California, challenged the negative stereotypes with an experiment where she consumed 80% ultra-processed food for a month. Contrary to expectations, Wilson reported she felt less hungry, experienced less fatigue, and was more physically active. She highlighted that UPFs are a significant part of the diet for many low-income families due to their affordability and convenience, and said that the public deserves more nuanced discussions rather than just "scary stories" about them. Her stance is partly driven by the view that fearmongering around UPFs overlooks socioeconomic factors like access to healthier alternatives. [52]

Environmental impact

Beyond health implications, the production of ultra-processed foods also has significant environmental impacts. [53] These foods require extensive processing and packaging, resulting in higher energy consumption and waste production compared to minimally processed foods. Moreover, the globalized supply chains for the ingredients of ultra-processed foods contribute to greenhouse gas emissions. [54]

Regulation and policy

Given the health and environmental impacts of ultra-processed foods, there have been calls for better regulation and policy surrounding these products. These measures face significant challenges, including industry opposition and the global nature of food supply chains. Future policy efforts may require a combination of regulation, education, and incentives to promote healthier, more sustainable food choices.

Four Latin American countries—Brazil, [55] Uruguay, [56] Peru, [57] and Ecuador [58] —have so far published national official dietary guidelines that recommend avoiding ultra-processed foods. Chile requires warning labels on some ultra-processed foods and taxes sugar-sweetened beverages. [59] A report on obesity published by the World Bank in 2020 mentions ultra-processed foods as a potential contributor. [60]

In 2022, the Scientific Advisory Committee on Nutrition (SACN) reviewed scientific literature to consider whether the British government should adopt a position on ultra-processed food and recommended further research, scheduling a review on its position for June 2024. [47]

Criticism

Following the publication of the Nova classification, some researchers questioned whether food processing should itself be considered a factor in nutrient intake, especially in a prominent 2017 criticism written by researchers, one of which was funded by Nestlé and the Kerry Group. [61] UPFs are imprecisely defined and it is unclear how any adverse effects on health may come about. [62]

In 2022, Carlos Monteiro and Arne Astrup argued for and against the Nova classification in a series of three articles written in the style of an Oxford debate. Monteiro's 'yes' argument states that the effects of ultra-processed food are demonstrated by representative dietary surveys and long-term cohort studies; that consuming ultra-processed food is associated with negative health outcomes; and that the associations are supported by discussions of specific mechanisms. [63] Astrup's 'no' argument states that the Nova definition of ultra-processed foods is ambiguous and inherently leads to misclassification of foods; that evidence is lacking for effects that are not already accounted for by known factors such as nutrient composition; that existing evidence is limited to observational studies rather than being supported by randomized controlled trials; and that some ultra-processing techniques are valuable in achieving the transition to sustainable food production. [64] The two researchers nonetheless agreed that food processing significantly affects diet quality and health outcomes; that most types of food processing are harmless or beneficial, with a minority being harmful; that some characteristics of food processing are useful for food classification systems; and that further study is required to understand the effect of food processing on human health. [65]

A number of studies show that although UPFs in general are associated with higher health risks, there exists a large heterogenity among UPF subgroups. For example, although bread and cereals are classfied as UPFs, a large 2023 study published in The Lancet finds them not associated with cancer and cardiometabolic diseases in the European population. [66] The study found that animal-based products and artificially and sugar-sweetened beverages are most strongly associated with diseases among UPFs. [67] Robinson and Johnstone (2024) cite a similar study conducted in the US population. They argue that there should be a balanced approach in approaching UPFs: consumers should not be prematurely advised to avoid all UPFs, not just because of physical health concerns, but also because of social costs of the removal of UPFs (unnecessary anxiety and mistrust of science). [68]

See also

Related Research Articles

<span class="mw-page-title-main">Abdominal obesity</span> Excess fat around the stomach and abdomen

Abdominal obesity, also known as central obesity and truncal obesity, is the human condition of an excessive concentration of visceral fat around the stomach and abdomen to such an extent that it is likely to harm its bearer's health. Abdominal obesity has been strongly linked to cardiovascular disease, Alzheimer's disease, and other metabolic and vascular diseases.

<span class="mw-page-title-main">Obesity</span> Medical condition in which excess body fat harms health

Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it can potentially have negative effects on health. People are classified as obese when their body mass index (BMI)—a person's weight divided by the square of the person's height—is over 30 kg/m2; the range 25–30 kg/m2 is defined as overweight. Some East Asian countries use lower values to calculate obesity. Obesity is a major cause of disability and is correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis.

<span class="mw-page-title-main">Human nutrition</span> Nutrients supporting human health

Human nutrition deals with the provision of essential nutrients in food that are necessary to support human life and good health. Poor nutrition is a chronic problem often linked to poverty, food security, or a poor understanding of nutritional requirements. Malnutrition and its consequences are large contributors to deaths, physical deformities, and disabilities worldwide. Good nutrition is necessary for children to grow physically and mentally, and for normal human biological development.

<span class="mw-page-title-main">Plant-based diet</span> Diet consisting mostly or entirely of plant-based foods

A plant-based diet is a diet consisting mostly or entirely of plant-based foods. Plant-based diets encompass a wide range of dietary patterns that contain low amounts of animal products and high amounts of fiber-rich plant products such as vegetables, fruits, whole grains, legumes, nuts and seeds. They do not need to be vegan or vegetarian, but are defined in terms of low frequency of animal food consumption.

<span class="mw-page-title-main">Maltodextrin</span> Polysaccharide of glucose

Maltodextrin is a name shared by two different families of chemicals. Both families are glucose polymers, but have little chemical or nutritional similarity.

<span class="mw-page-title-main">Healthy diet</span> Type of diet

A healthy diet is a diet that maintains or improves overall health. A healthy diet provides the body with essential nutrition: fluid, macronutrients such as protein, micronutrients such as vitamins, and adequate fibre and food energy.

<span class="mw-page-title-main">Refined grains</span> Cereal containing endosperm, but not bran nor germ

Refined grains have been significantly modified from their natural composition, in contrast to whole grains. The modification process generally involves the mechanical removal of bran and germ, either through grinding or selective sifting.

<span class="mw-page-title-main">Antinutrient</span> Compound that affects the absorption of nutrients

Antinutrients are natural or synthetic compounds that interfere with the absorption of nutrients. Nutrition studies focus on antinutrients commonly found in food sources and beverages. Antinutrients may take the form of drugs, chemicals that naturally occur in food sources, proteins, or overconsumption of nutrients themselves. Antinutrients may act by binding to vitamins and minerals, preventing their uptake, or inhibiting enzymes.

<span class="mw-page-title-main">Diet and obesity</span> Effect of diet on obesity


Diet plays an important role in the genesis of obesity. Personal choices, food advertising, social customs and cultural influences, as well as food availability and pricing all play a role in determining what and how much an individual eats.

<span class="mw-page-title-main">Weight management</span> Techniques for maintaining body weight

Weight management refers to behaviors, techniques, and physiological processes that contribute to a person's ability to attain and maintain a healthy weight. Most weight management techniques encompass long-term lifestyle strategies that promote healthy eating and daily physical activity. Moreover, weight management involves developing meaningful ways to track weight over time and to identify the ideal body weights for different individuals.

<span class="mw-page-title-main">Health effects of salt</span> Conditions associated with the consumption of either too much or too little salt

The health effects of salt are the conditions associated with the consumption of either too much or too little salt. Salt is a mineral composed primarily of sodium chloride (NaCl) and is used in food for both preservation and flavor. Sodium ions are needed in small quantities by most living things, as are chloride ions. Salt is involved in regulating the water content of the body. The sodium ion itself is used for electrical signaling in the nervous system.

Nutrition psychology is the psychological study of the relationship between dietary intake and different aspects of psychological health. It is an applied field that uses an interdisciplinary approach to examine the influence of diet on mental health. Nutrition psychology seeks to understand the relationship between nutritional behavior, mental health and general well-being. It is a sub-field of psychology and more specifically of health psychology, and may be applied to numerous related fields, including psychology, dietetics, nutrition, and marketing.

<span class="mw-page-title-main">Added sugar</span> Caloric sweeteners added to food and beverages

Added sugars or free sugars are sugar carbohydrates added to food and beverages at some point before their consumption. These include added carbohydrates, and more broadly, sugars naturally present in honey, syrup, fruit juices and fruit juice concentrates. They can take multiple chemical forms, including sucrose, glucose (dextrose), and fructose.

The Australian paradox is an observation of diverging trends in sugar consumption and obesity rates in Australia. The term was first used in a 2011 study published in Nutrients by Professor Jennie Brand-Miller, in which she and co-author Dr. Alan Barclay reported that, in Australia, "a substantial decline in refined sugars intake occurred over the same timeframe that obesity has increased."

<span class="mw-page-title-main">Preventive nutrition</span> Branch of nutrition science

Preventive Nutrition is a branch of nutrition science with the goal of preventing, delaying, and/or reducing the impacts of disease and disease-related complications. It is concerned with a high level of personal well-being, disease prevention, and diagnosis of recurring health problems or symptoms of discomfort which are often precursors to health issues. The overweight and obese population numbers have increased over the last 40 years and numerous chronic diseases are associated with obesity. Preventive nutrition may assist in prolonging the onset of non-communicable diseases and may allow adults to experience more "healthy living years." There are various ways of educating the public about preventive nutrition. Information regarding preventive nutrition is often communicated through public health forums, government programs and policies, or nutritional education. For example, in the United States, preventive nutrition is taught to the public through the use of the food pyramid or MyPlate initiatives.

<span class="mw-page-title-main">Geoffrey Cannon</span> English journalist and scholar

Geoffrey Cannon is an English author, journalist and former magazine editor, and scholar. From 1968 to 1972, he was the music critic for The Guardian, a role that made him the first dedicated rock critic at a British daily newspaper. Having worked as the arts editor for New Society magazine, he became editor of the BBC publication Radio Times from 1969 to 1979. During that time, he also wrote on music and popular culture for The Listener, the Los Angeles Times, the Chicago Sun-Times, Creem, Rock et Folk, Melody Maker and Time Out.

<span class="mw-page-title-main">Hyperpalatable food</span> Food that triggers the brains reward system

Hyperpalatable food (HPF) combines high levels of fat, sugar, sodium, and/or carbohydrates to trigger the brain's reward system, encouraging excessive eating. The concept of hyperpalatability is foundational to ultra-processed foods, which are usually engineered to have enjoyable qualities of sweetness, saltiness, or richness. Hyperpalatable foods can stimulate the release of metabolic, stress, and appetite hormones that play a role in cravings and may interfere with the body's ability to regulate appetite and satiety.

<span class="mw-page-title-main">Nova classification</span> System of food processing groups

The Nova classification is a framework for grouping edible substances based on the extent and purpose of food processing applied to them. Researchers at the University of São Paulo, Brazil, proposed the system in 2009.

Carlos Augusto Monteiro is a Brazilian epidemiologist who coined the term ultra-processed food and introduced the Nova classification.

<span class="mw-page-title-main">Health effects of ultra-processed foods</span>

Ultra-processed foods (UPFs) are industrially manufactured foods that are designed to be convenient, palatable, and affordable. These foods often contain multiple ingredients and additives such as preservatives, sweeteners, colorings, and emulsifiers, which are not typically found in home kitchens. They tend to be low in fiber and high in calories, salt, added sugar and fat, which are all related to poor health outcomes when eaten excessively. Common examples include packaged snacks, soft drinks, ready meals, and processed meats.

References

  1. Monteiro C (2010). "The big issue is ultra-processing". World Nutrition. 1 (6): 237–269. ISSN   2041-9775.
  2. Monteiro C (2011). "The big issue is ultra-processing. Why bread, hot dogs – and margarine – are ultra-processed". World Nutrition. 2 (10): 534–549. ISSN   2041-9775.
  3. 1 2 Monteiro CA, Cannon G, Levy RB, Moubarac JC, Louzada ML, Rauber F, et al. (April 2019). "Ultra-processed foods: what they are and how to identify them". Public Health Nutrition. 22 (5): 936–941. doi: 10.1017/S1368980018003762 . PMC   10260459 . PMID   30744710.
  4. 1 2 3 Touvier M, da Costa Louzada ML, Mozaffarian D, Baker P, Juul F, Srour B (October 2023). "Ultra-processed foods and cardiometabolic health: public health policies to reduce consumption cannot wait". BMJ. 383: e075294. doi: 10.1136/bmj-2023-075294 . PMC   10561017 . PMID   37813465.
  5. 1 2 Fardet A (2018). "Characterization of the Degree of Food Processing in Relation With Its Health Potential and Effects". Advances in Food and Nutrition Research. Vol. 85. Elsevier. pp. 79–129. doi:10.1016/bs.afnr.2018.02.002. ISBN   978-0-12-815089-4. PMID   29860978.
  6. 1 2 Monteiro CA, Levy RB, Claro RM, Castro IR, Cannon G (November 2010). "A new classification of foods based on the extent and purpose of their processing". Cadernos de Saude Publica. 26 (11): 2039–2049. doi: 10.1590/S0102-311X2010001100005 . PMID   21180977.
  7. 1 2 3 Gibney MJ (February 2019). "Ultra-Processed Foods: Definitions and Policy Issues". Current Developments in Nutrition. 3 (2): nzy077. doi:10.1093/cdn/nzy077. PMC   6389637 . PMID   30820487.
  8. Dixon R (Sep 6, 2023). "Ultra-processed foods: the 19 things everyone needs to know". The Guardian . Retrieved Sep 24, 2024.
  9. 1 2 3 Monteiro CA (May 2009). "Nutrition and health. The issue is not food, nor nutrients, so much as processing". Public Health Nutrition. 12 (5): 729–731. doi: 10.1017/S1368980009005291 . PMID   19366466. S2CID   42136316.
  10. 1 2 3 Lockyer S, Spiro A, Berry S, He J, Loth S, Martinez-Inchausti A, et al. (June 2023). "How do we differentiate not demonise - Is there a role for healthier processed foods in an age of food insecurity? Proceedings of a roundtable event". Nutrition Bulletin. 48 (2): 278–295. doi:10.1111/nbu.12617. PMID   37164357. S2CID   258618401.
  11. 1 2 3 Lane MM, Gamage E, Du S, Ashtree DN, McGuinness AJ, Gauci S, et al. (February 2024). "Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses". BMJ. 384: e077310. doi:10.1136/bmj-2023-077310. PMC   10899807 . PMID   38418082.
  12. 1 2 Pagliai G, Dinu M, Madarena MP, Bonaccio M, Iacoviello L, Sofi F (February 2021). "Consumption of ultra-processed foods and health status: a systematic review and meta-analysis". The British Journal of Nutrition. 125 (3): 308–318. doi:10.1017/S0007114520002688. PMC   7844609 . PMID   32792031.
  13. 1 2 Visioli F, Marangoni F, Fogliano V, Del Rio D, Martinez JA, Kuhnle G, et al. (December 2023). "The ultra-processed foods hypothesis: a product processed well beyond the basic ingredients in the package". Nutrition Research Reviews. 36 (2): 340–350. doi:10.1017/S0954422422000117. hdl: 11577/3451280 . PMID   35730561.
  14. Valicente VM, Peng CH, Pacheco KN, Lin L, Kielb EI, Dawoodani E, et al. (July 2023). "Ultraprocessed Foods and Obesity Risk: A Critical Review of Reported Mechanisms". Advances in Nutrition. 14 (4): 718–738. doi:10.1016/j.advnut.2023.04.006. PMC   10334162 . PMID   37080461.
  15. Moubarac JC, Parra DC, Cannon G, Monteiro CA (June 2014). "Food Classification Systems Based on Food Processing: Significance and Implications for Policies and Actions: A Systematic Literature Review and Assessment". Current Obesity Reports. 3 (2): 256–272. doi:10.1007/s13679-014-0092-0. PMID   26626606. S2CID   23606942.
  16. Pollan M (2006). The omnivore's dilemma: A natural history of four meals. New York: Penguin Press. ISBN   978-1-59420-082-3.
  17. LaMotte S (February 1, 2024). "You may be eating predigested food. Here's why". CNN.
  18. O'Connor A, Steckelberg A (June 27, 2023). "Melted, pounded, extruded: Why many ultra-processed foods are unhealthy". Washington Post.
  19. Al-Sibai N (February 3, 2024). "Experts Warn That the Food You're Eating May Have Been "Pre-Digested". Futurism.
  20. Boyce H (February 5, 2024). "You might be eating 'predigested' food. Seriously". Atlanta Journal-Constitution.
  21. Fardet A, Rock E (November 2019). "Ultra-processed foods: A new holistic paradigm?". Trends in Food Science & Technology. 93: 174–184. doi:10.1016/j.tifs.2019.09.016. ISSN   0924-2244. S2CID   203896042.
  22. Sadler CR, Grassby T, Hart K, Raats M, Sokolović M, Timotijevic L (June 2021). "Processed food classification: Conceptualisation and challenges". Trends in Food Science & Technology. 112: 149–162. doi: 10.1016/j.tifs.2021.02.059 . ISSN   0924-2244. S2CID   233647428.
  23. Hässig A, Hartmann C, Sanchez-Siles L, Siegrist M (August 2023). "Perceived degree of food processing as a cue for perceived healthiness: The NOVA system mirrors consumers' perceptions". Food Quality and Preference. 110: 104944. doi: 10.1016/j.foodqual.2023.104944 . hdl: 20.500.11850/625580 . ISSN   0950-3293. S2CID   259941132.
  24. Ares G, Vidal L, Allegue G, Giménez A, Bandeira E, Moratorio X, et al. (October 2016). "Consumers' conceptualization of ultra-processed foods". Appetite. 105: 611–617. doi:10.1016/j.appet.2016.06.028. PMID   27349706. S2CID   3554621.
  25. Darmon N (October 2009). "The good, the bad, and the ultra-processed". Public Health Nutrition. 12 (10): 1967–1968. doi: 10.1017/S1368980009991212 . PMID   19732488. S2CID   233340283.
  26. Fazzino TL, Rohde K, Sullivan DK (November 2019). "Hyper-Palatable Foods: Development of a Quantitative Definition and Application to the US Food System Database". Obesity. 27 (11): 1761–1768. doi:10.1002/oby.22639. hdl: 1808/29721 . PMID   31689013. S2CID   207899275.
  27. Martinez-Steele E, Khandpur N, Batis C, Bes-Rastrollo M, Bonaccio M, Cediel G, et al. (June 2023). "Best practices for applying the Nova food classification system". Nature Food. 4 (6): 445–448. doi:10.1038/s43016-023-00779-w. PMID   37264165. S2CID   259024679.
  28. Chajès V, Biessy C, Byrnes G, Deharveng G, Saadatian-Elahi M, Jenab M, et al. (November 2011). "Ecological-level associations between highly processed food intakes and plasma phospholipid elaidic acid concentrations: results from a cross-sectional study within the European prospective investigation into cancer and nutrition (EPIC)". Nutrition and Cancer. 63 (8): 1235–1250. doi:10.1080/01635581.2011.617530. PMID   22043987. S2CID   23413731.
  29. Slimani N, Deharveng G, Southgate DA, Biessy C, Chajès V, van Bakel MM, et al. (November 2009). "Contribution of highly industrially processed foods to the nutrient intakes and patterns of middle-aged populations in the European Prospective Investigation into Cancer and Nutrition study". European Journal of Clinical Nutrition. 63 (Suppl 4): S206–S225. doi:10.1038/ejcn.2009.82. PMID   19888275.
  30. Davidou S, Christodoulou A, Fardet A, Frank K (March 2020). "The holistico-reductionist Siga classification according to the degree of food processing: an evaluation of ultra-processed foods in French supermarkets". Food & Function. 11 (3): 2026–2039. doi:10.1039/C9FO02271F. PMID   32083627. S2CID   211231016.
  31. Fardet A (October 2018). "Vers une classification des aliments selon leur degré de transformation: Approches holistique et/ou réductionniste". Pratiques en Nutrition (in French). 14 (56): 32–36. doi:10.1016/j.pranut.2018.09.008. S2CID   187435561.
  32. Eicher-Miller HA, Fulgoni VL, Keast DR (June 2015). "Energy and Nutrient Intakes from Processed Foods Differ by Sex, Income Status, and Race/Ethnicity of US Adults". Journal of the Academy of Nutrition and Dietetics. 115 (6): 907–18.e6. doi:10.1016/j.jand.2014.11.004. PMID   25578928.
  33. Eicher-Miller HA, Fulgoni VL, Keast DR (November 2012). "Contributions of processed foods to dietary intake in the US from 2003-2008: a report of the Food and Nutrition Science Solutions Joint Task Force of the Academy of Nutrition and Dietetics, American Society for Nutrition, Institute of Food Technologists, and International Food Information Council". The Journal of Nutrition. 142 (11): 2065S–2072S. doi:10.3945/jn.112.164442. PMC   3593301 . PMID   22990468.
  34. Louzada ML, Baraldi LG, Steele EM, Martins AP, Canella DS, Moubarac JC, et al. (December 2015). "Consumption of ultra-processed foods and obesity in Brazilian adolescents and adults". Preventive Medicine. 81: 9–15. doi:10.1016/j.ypmed.2015.07.018. PMID   26231112.
  35. 1 2 Gupta S, Hawk T, Aggarwal A, Drewnowski A (2019-05-28). "Characterizing Ultra-Processed Foods by Energy Density, Nutrient Density, and Cost". Frontiers in Nutrition. 6: 70. doi: 10.3389/fnut.2019.00070 . PMC   6558394 . PMID   31231655.
  36. 1 2 Monteiro CA, Moubarac JC, Cannon G, Ng SW, Popkin B (November 2013). "Ultra-processed products are becoming dominant in the global food system". Obesity Reviews. 14 (Suppl 2): 21–28. doi: 10.1111/obr.12107 . PMID   24102801.
  37. Stuckler D, Nestle M (2012-06-19). "Big food, food systems, and global health". PLOS Medicine. 9 (6): e1001242. doi: 10.1371/journal.pmed.1001242 . PMC   3378592 . PMID   22723746.
  38. Baker P, Machado P, Santos T, Sievert K, Backholer K, Hadjikakou M, et al. (December 2020). "Ultra-processed foods and the nutrition transition: Global, regional and national trends, food systems transformations and political economy drivers". Obesity Reviews. 21 (12): e13126. doi:10.1111/obr.13126. hdl: 11343/276118 . PMID   32761763.
  39. Monteiro CA, Cannon G, Moubarac JC, Levy RB, Louzada ML, Jaime PC (January 2018). "The UN Decade of Nutrition, the NOVA food classification and the trouble with ultra-processing". Public Health Nutrition. 21 (1): 5–17. doi: 10.1017/S1368980017000234 . PMC   10261019 . PMID   28322183.
  40. Montgomery K, Chester J, Nixon L, Levy L, Dorfman L (January 2019). "Big Data and the transformation of food and beverage marketing: undermining efforts to reduce obesity?". Critical Public Health. 29 (1): 110–117. doi:10.1080/09581596.2017.1392483. ISSN   0958-1596.
  41. Mialon M, Gaitan Charry DA, Cediel G, Crosbie E, Scagliusi FB, Perez Tamayo EM (June 2021). "'I had never seen so many lobbyists': food industry political practices during the development of a new nutrition front-of-pack labelling system in Colombia". Public Health Nutrition. 24 (9): 2737–2745. doi:10.1017/s1368980020002268. PMC   10195544 . PMID   32819452.
  42. Slater S, Lawrence M, Wood B, Serodio P, Baker P (February 2024). "Corporate interest groups and their implications for global food governance: mapping and analysing the global corporate influence network of the transnational ultra-processed food industry". Globalization and Health. 20 (1): 16. doi: 10.1186/s12992-024-01020-4 . PMC   10882744 . PMID   38388413.
  43. Isaksen IM, Dankel SN (June 2023). "Ultra-processed food consumption and cancer risk: A systematic review and meta-analysis". Clinical Nutrition. 42 (6): 919–928. doi:10.1016/j.clnu.2023.03.018. PMID   37087831. S2CID   257872002.
  44. Chen Z, Khandpur N, Desjardins C, Wang L, Monteiro CA, Rossato SL, et al. (July 2023). "Ultra-Processed Food Consumption and Risk of Type 2 Diabetes: Three Large Prospective U.S. Cohort Studies". Diabetes Care. 46 (7): 1335–1344. doi:10.2337/dc22-1993. PMC   10300524 . PMID   36854188.
  45. LaFata EM, Gearhardt AN (2022-11-07). "Ultra-Processed Food Addiction: An Epidemic?". Psychotherapy and Psychosomatics. 91 (6): 363–372. doi:10.1159/000527322. PMID   36349805.
  46. Kliemann N, Al Nahas A, Vamos EP, Touvier M, Kesse-Guyot E, Gunter MJ, et al. (July 2022). "Ultra-processed foods and cancer risk: from global food systems to individual exposures and mechanisms". British Journal of Cancer. 127 (1): 14–20. doi:10.1038/s41416-022-01749-y. hdl:10362/153976. PMC   9276654 . PMID   35236935.
  47. 1 2 Scientific Advisory Committee on Nutrition (2023-07-11). "SACN statement on processed foods and health". GOV.UK.
  48. Kelly A (December 9, 2019). "Demonising processed food undermines our trust in science". The Conversation . Retrieved Sep 24, 2024.
  49. Schober C (2024-08-29). "Time Magazine Suggests Ultra-Processed Foods Really Aren't That Bad, And The Comments Are Hilarious". Evie Magazine. Retrieved 2024-09-19.
  50. Nichols L (2024-05-20). "Beyond the Headlines: Unpacking the Truth About "Ultra-Processed" Foods and Health". Consumer Brands Association. Retrieved 2024-09-19.
  51. "Here are the surprising results a dietitian got after eating ultra-processed food for a whole month". scoop.upworthy.com. 2024-09-04. Retrieved 2024-09-19.
  52. Ducharme J (2024-08-27). "Why One Dietitian is Speaking Up for "Ultra-Processed" Foods". TIME. Retrieved 2024-09-19.
  53. Leite FH, Khandpur N, Andrade GC, Anastasiou K, Baker P, Lawrence M, et al. (March 2022). "Ultra-processed foods should be central to global food systems dialogue and action on biodiversity". BMJ Global Health. 7 (3): e008269. doi:10.1136/bmjgh-2021-008269. PMC   8895941 . PMID   35346976.
  54. Seferidi P, Scrinis G, Huybrechts I, Woods J, Vineis P, Millett C (October 2020). "The neglected environmental impacts of ultra-processed foods". The Lancet. Planetary Health. 4 (10): e437–e438. doi: 10.1016/S2542-5196(20)30177-7 . hdl: 11343/252595 . PMID   33038314. S2CID   222280757.
  55. Dietary Guidelines for the Brazilian Population (Report). Brasília: Brazilian Ministry of Health. 2014.
  56. "Guías Alimentarias para la Población Uruguaya". Montevideo: Ministerio de Salud del Uruguay. 2016.
  57. Guías Alimentarias para la Población Peruana (Report). Lima: Ministerio de Salud del Perú. 2018.
  58. Documento Técnico de las Guías Alimentarias Basadas en Alimentos (GABA) del Ecuador. GABA-ECU (Report). Quito: Ministerio de Salud Pública del Ecuador y Organización de las Naciones Unidas para la Alimentación y la Agricultura. 2018.
  59. Colchero MA, Paraje G, Popkin BM (2021-12-02). Vadiveloo MK (ed.). "The impacts on food purchases and tax revenues of a tax based on Chile's nutrient profiling model". PLOS ONE. 16 (12): e0260693. Bibcode:2021PLoSO..1660693C. doi: 10.1371/journal.pone.0260693 . PMC   8638973 . PMID   34855853.
  60. Shekar M, Popkin B (2020-02-13). Shekar M, Popkin B (eds.). Obesity: Health and economic consequences of an impending global challenge. The World Bank. doi:10.1596/978-1-4648-1491-4. hdl:10986/32383. ISBN   978-1-4648-1491-4. S2CID   219141840.
  61. Gibney MJ, Forde CG, Mullally D, Gibney ER (September 2017). "Ultra-processed foods in human health: a critical appraisal". The American Journal of Clinical Nutrition. 106 (3): 717–724. doi: 10.3945/ajcn.117.160440 . PMID   28793996.
  62. Tobias DK, Hall KD (December 2021). "Eliminate or reformulate ultra-processed foods? Biological mechanisms matter". Cell Metabolism. 33 (12): 2314–2315. doi: 10.1016/j.cmet.2021.10.005 . PMID   34699743. S2CID   239986991.
  63. Monteiro CA, Astrup A (December 2022). "Does the concept of "ultra-processed foods" help inform dietary guidelines, beyond conventional classification systems? YES". The American Journal of Clinical Nutrition. 116 (6): 1476–1481. doi: 10.1093/ajcn/nqac122 . PMID   35670127.
  64. Astrup A, Monteiro CA (December 2022). "Does the concept of "ultra-processed foods" help inform dietary guidelines, beyond conventional classification systems? NO". The American Journal of Clinical Nutrition. 116 (6): 1482–1488. doi: 10.1093/ajcn/nqac123 . PMID   35670128.
  65. Astrup A, Monteiro CA (December 2022). "Does the concept of "ultra-processed foods" help inform dietary guidelines, beyond conventional classification systems? Debate consensus". The American Journal of Clinical Nutrition. 116 (6): 1489–1491. doi: 10.1093/ajcn/nqac230 . PMID   36253965.
  66. Campbell D (13 November 2023). "Some ultra-processed foods are good for your health, WHO-backed study finds". The Guardian.
  67. Cordova R, Viallon V, Fontvieille E, Peruchet-Noray L, Jansana A, Wagner KH, et al. (December 2023). "Consumption of ultra-processed foods and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study". The Lancet Regional Health - Europe. 35: 100771. doi:10.1016/j.lanepe.2023.100771. PMID   38115963.
  68. Robinson E, Johnstone AM (15 October 2024). "Ultraprocessed food (UPF), health, and mechanistic uncertainty: What should we be advising the public to do about UPFs?". PLOS Medicine. 21 (10): e1004439. doi: 10.1371/journal.pmed.1004439 . PMID   39405438.