United States Preventive Services Task Force

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The United States Preventive Services Task Force (USPSTF) is "an independent panel of experts in primary care and prevention that systematically reviews the evidence of effectiveness and develops recommendations for clinical preventive services". [1] The task force, a volunteer panel of primary care clinicians (including those from internal medicine, pediatrics, family medicine, obstetrics and gynecology, nursing, and psychology) with methodology experience including epidemiology, biostatistics, health services research, decision sciences, and health economics, is funded, staffed, and appointed by the U.S. Department of Health and Human Services' Agency for Healthcare Research and Quality. [2] [3]

Contents

Intent

The USPSTF evaluates scientific evidence to determine whether medical screenings, counseling, and preventive medications work for adults and children who have no symptoms.

Methods

The methods of evidence synthesis used by the Task Force have been described in detail. [4] In 2007, their methods were revised. [5] [6]

No weight given to cost-effectiveness

The USPSTF explicitly does not consider cost as a factor in its recommendations, and it does not perform cost-effectiveness analyses. [7] American health insurance groups are required to cover, at no charge to the patient, any service that the USPSTF recommends, regardless of how much it costs or how small the benefit is. [8]

Grade definitions

The task force assigns the letter grades A, B, C, D, or I to each of its recommendations, and includes "suggestions for practice" for each grade. The Task Force also defined levels of certainty regarding net benefit. [9]

GradeResultMeaning
Grade ARecommendedThere is high certainty that the net benefit is substantial.
Grade BRecommendedThere is high certainty that the net benefit is moderate or there is moderate certainty that the net benefit is moderate to substantial.
Grade CNo recommendationClinicians may provide the service to selected patients depending on individual circumstances. However, for most individuals without signs or symptoms there is likely to be only a small benefit.
Grade DRecommended againstThe Task Force recommends against this service. There is moderate or high certainty that the service has no net benefit or that the harms outweigh the benefits.
I statementInsufficient evidenceThe current evidence is insufficient to assess the balance of benefits and harms.

Levels of certainty vary from high to low according to the evidence.

The USPSTF has evaluated many interventions for prevention and found several have an expected net benefit in the general population. [10]

Breast cancer screening

The USPSTF has changed its breast cancer screening recommendations over the years, including at what age women should begin routine screening. In 2009, the task force recommended women at average risk for developing breast cancer should be screened with mammograms every two years beginning at age 50. [12] Previously, they had recommended beginning screening at age 40. The recommendation to begin screening at an older age received significant attention, including proposed congressional intervention. [13] The 2016 recommendations maintained 50 as the age when routine screening should begin. [14]

In April 2024, The USPSTF lowered the recommended age to begin breast cancer screening. Citing rising rates of breast cancer diagnosis and substantially higher rates among Black women in the United States, the task force recommends screening mammograms every two years beginning at age 40. This recommendation applies to all cisgender women and all other people assigned female at birth who are at average risk for breast cancer. [15] [16] [17]

Prostate cancer screening

In the current recommendation published in 2018, the Task Force recommended that prostate-specific antigen (PSA)-based screening for prostate cancer screenings be an individual decision for men between the ages of 55 to 69. [18] In 2018 the Task Force gave PCa screening a C recommendation. [18]

A final statement published in 2018 recommends basing the decision to screen on shared decision making in those 55 to 69 years old. [19] It continues to recommend against screening in those 70 and older. [19]

History

The initial USPSTF was created in 1984 as a 5 year appointment to "develop recommendations for primary care clinicians on the appropriate content of periodic health examinations" and was modelled on the Canadian Task Force on Preventive Health Care, established in 1976. [20] This initial 5 year project concluded in 1989 with the release of their report, the Guide to Clinical Preventive Services. In July 1990, the Department of Health and Human Services reconstituted the Task Force to continue and update these scientific assessments of preventive services. [21]

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References

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  16. Johnson, Carla (April 30, 2024), "Breast cancer is on the rise in women in their 40s. An earlier mammogram may help catch it sooner", Associated Press
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  18. 1 2 "Screening for Prostate Cancer Recommendation Statement". US Preventive Services Task Force. October 2022.
  19. 1 2 "Prostate Cancer: Screening: Screening". US Preventive Services Task. Retrieved 10 October 2022.
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