In a secret military laboratory operating under the guise of a pesticide manufacturer, a sealed tube is broken, starting an outbreak of a virulent bacteria. Detecting the release of the biological weapon, Joanie Morse, the plant's security officer, activates "Protocol One," a procedure sealing all of the workers inside from the outside world.
Tom Schmidt, believing the cause for the lock down to be a pump malfunction, and co-worker Bob restart the pump. In the biohazard P4 lab, Dr. Nielsen contacts Security, confirms "Protocol One", and advises Security to open the safe and contact USACT, the United States government's Accident Containment Team, to deal with the problem.
Cal Morse, a County Sheriff and Joanie's husband, is advised to retain the help of Dr. Dan Fairchild, a past employee who is a known alcoholic. Fairchild created an antidote to the weapon. Vic Flint, frustrated over the quarantine of his son Bob, attempts to shoot his way in. Fearing someone being shot accidentally, Cal confiscates his revolver after the bullet ricochets off the blast doors.
USACT, led by Major Connelly, arrives and sets up quarantine procedures. Connelly appeases the public with the cover story of a contamination of experimental yeast while a rescue team arrives to administer the antidote to the workers.
Upon the release of the weapon, the P4 lab workers sanitize the area, destroy lab animals, and inoculate themselves with the antidote. Hours later, the USACT team locate Nielsen and his team incapacitated on the floor near the P4 lab air lock. They later notice that the bodies have disappeared, the air lock smashed open from inside, and a power outage from inside the building caused by Dr. Ramesh Kapoor, a P4 worker, by destroying a power box.
A group of workers—including Bob, Schmidt, and Tippett—believe themselves to be unaffected and want to leave, despite the quarantine. Unbeknownst to the workers, they became infected by the breach of the air lock, the bypassed pump circulating contaminated air throughout the building, and Schmidt's contact lens contaminating the building with the weapon. Joanie destroyed the piece of paper containing the code to deactivate the lockdown, but remembers the code. The group, now led by Tippett, torture her for the code, which is discovered to be invalidated once USACT tapped into the system.
The rescue team eventually encounters this group of workers. The team order the group to remain under quarantine; Tippett is shot dead when he refuses. The rest are placed in a room to await inoculation when the team returns with the antidote.
Fairchild directs the team into an unoccupied service conduit as a direct way to the P4 lab. The team encounters Nielsen. Suspecting something to be wrong, Fairchild directs the team to retreat, leaving Nielsen behind. The team are ambushed and murdered by the P4 workers, one of which is murdered by Kapoor. Despite being inoculated, the antidote did not work; suffering from the effects of the weapon, all of the infected workers become enraged, homicidal maniacs.
Upon the rescue team's death, USACT activates "Protocol Two", leaving all employees to await the deadly effects of the weapon and sanitize the location afterwards. Hearing this, Cal urges Fairchild to assist him in retrieving the antidote, stopping the contagion, and saving Joanie. At the facility, Cal and Fairchild encounter an infected Bob. He tries to attack, but is shot dead by Cal, armed with the revolver.
Most of the workers succumb to their infections, but somehow Joanie is unaffected. Schmidt covinces her to go to the P4 lab to retrieve the antidote. En route, they encounter Nielsen, who wants to contain the knowledge of the incident, and Kapoor, who wants to kill them. They eventually escape the attack.
While in the P4 lab, Schmidt succumbs to his infection. Untreated, he becomes enraged as the P4 workers hunt them down. Joanie retrieves the antidote and flees while Schmidt attacks the P4 workers, breaking Kapoor's neck before being killed by the rest.
Joanie eventually encounters Cal and Fairchild. They later repel a group of workers who rip Fairchild's biohazard suit, exposing him. They enter the P4 lab to learn why Joanie is unaffected while the antidote did not work. A test discovers that her blood is full of estrogen, progesterone, and antibodies; she is pregnant. While attempting to enter P4 to attack the trio, workers are set on fire by booby traps. One worker rips Cal's biohazard suit before being killed by Joanie.
Before being incapacitated by his infection, Fairchild enters a recipe for a new antidote based on Joanie's condition into a computer; it contains thorazine to make the patient sleep during their recuperation. Using Fairchild as a guinea pig, they try out the new antidote on him; it works.
Armed with injection guns, Cal and Fairchild inoculate infected workers while Joanie takes a batch of the new antidote to the building's decontamination system. Nielsen, refusing to be injected, flees back to the lab. Celebrating their success, Fairchild reveals that their new antidote works. Realizing his failure, Nielsen commits suicide with the revolver Cal left behind.
Using the decontamination system, Joanie administers the new antidote throughout the building, eradicating the weapon and treating workers breathing in the aerosolized antidote. Joanie then deactivates the quarantine and Fairchild inoculates Cal.
The crisis over, USACT evacuates the victims, retrieves the dead and seals the building. Cal later nails a "DO NOT ENTER" sign on the entrance. Fairchild invites Cal and Joanie back to his home for breakfast - Zucchini pancakes and genetically modified corn on the cob.
Warning Sign has an approval rating of 20% on Rotten Tomatoes, based on 10 reviews.[3]
Rick Kogan of the Chicago Tribune wrote: "Warning Sign fails to deliver any substantive messages or any genuine thrills."[4]
The original title was Biohazard, which tested poorly with preview audiences, and the film was retitled but used the biohazard sign on the poster.[5]
Related Research Articles
Biosafety is the prevention of large-scale loss of biological integrity, focusing both on ecology and human health. These prevention mechanisms include the conduction of regular reviews of biosafety in laboratory settings, as well as strict guidelines to follow. Biosafety is used to protect from harmful incidents. Many laboratories handling biohazards employ an ongoing risk management assessment and enforcement process for biosafety. Failures to follow such protocols can lead to increased risk of exposure to biohazards or pathogens. Human error and poor technique contribute to unnecessary exposure and compromise the best safeguards set into place for protection.
A biological hazard, or biohazard, is a biological substance that poses a threat to the health of living organisms, primarily humans. This could include a sample of a microorganism, virus or toxin that can adversely affect human health. A biohazard could also be a substance harmful to other living beings.
The 2002–2004 outbreak of SARS, caused by severe acute respiratory syndrome coronavirus, infected over 8,000 people from 30 countries and territories, and resulted in at least 774 deaths worldwide.
Rinderpest was an infectious viral disease of cattle, domestic buffalo, and many other species of even-toed ungulates, including gaurs, buffaloes, large antelope, deer, giraffes, wildebeests, and warthogs. The disease was characterized by fever, oral erosions, diarrhea, lymphoid necrosis, and high mortality. Death rates during outbreaks were usually extremely high, approaching 100% in immunologically naïve populations. Rinderpest was mainly transmitted by direct contact and by drinking contaminated water, although it could also be transmitted by air.
Cold Fear is a 2005 survival horror third-person shooter video game developed by Darkworks and published by Ubisoft for PlayStation 2, Xbox and Microsoft Windows. It was Darkworks' second game, after Alone in the Dark: The New Nightmare in 2001. The game is centered on Tom Hansen, a member of the United States Coast Guard, who comes to the aid of a Russian whaler in the Bering Strait and finds a mysterious parasite has turned the crew into zombie-like creatures. Discovering the involvement of both the Russian mafia and the CIA, Hansen sets out to ensure the parasites don't reach land.
The Hot Zone: A Terrifying True Story is a best-selling 1994 nonfiction thriller by Richard Preston about the origins and incidents involving viral hemorrhagic fevers, particularly ebolaviruses and marburgviruses. The basis of the book was Preston's 1992 New Yorker article "Crisis in the Hot Zone".
"Babel" is the fifth episode of the American science fiction television series Star Trek: Deep Space Nine. The episode aired on television on January 25, 1993.
Doomsday is a 2008 science fiction action film written and directed by Neil Marshall. The film takes place in the future in Scotland, which has been quarantined because of a deadly virus. When the virus is found in London, political leaders send a team led by Major Eden Sinclair to Scotland to find a possible cure. Sinclair's team runs into two types of survivors: marauders and medieval knights. Doomsday was conceived by Marshall based on the idea of futuristic soldiers facing medieval knights. In producing the film, he drew inspiration from various movies, including Mad Max, Escape from New York and 28 Days Later.
Smallpox was an infectious disease caused by variola virus, which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, making smallpox the only human disease to have been eradicated to date.
Dead Space is a 1991 American science-fiction horror film directed by Fred Gallo and produced by Mike Elliott for Roger Corman's Concorde Pictures. It was a remake of Corman's Forbidden World (1982). According to writer Chris Koetting, "The plot was essentially the same— although this time the scientists were trying to find a cure for an AIDS-type virus— but the sex and gore quotient was substantially reduced, and the monster was even less convincing than the one that was fabricated by Steve Neill in 1982."
Dr. Venom is a fictional character who appears in the Marvel G.I. Joe comic series. He is a scientist who is the inventor of the Brainwave Scanner.
Resident Evil: Operation Raccoon City is a squad-based third-person shooter video game for Microsoft Windows, PlayStation 3 and Xbox 360, co-developed by Slant Six Games and Capcom. It was released on March 20, 2012 in North America, March 22, 2012 in Australia, March 23, 2012 in Europe and April 26, 2012 in Japan.
The Amazing Spider-Man is a 2012 action-adventure game. It was developed by Beenox and published by Activision. Based on the Marvel Comics character Spider-Man and the 2012 film of the same name. It was released on June 26 in North America and on June 29, 2012 in Europe for the Nintendo DS, PlayStation 3, Xbox 360, Wii, Nintendo 3DS, Android, iOS, and Microsoft Windows. A version for the Wii U was released in March 2013 in North America and Europe known as The Amazing Spider-Man: Ultimate Edition in both regions. A PlayStation Vita version was released in November 2013.
The San Francisco plague of 1900–1904 was an epidemic of bubonic plague centered on San Francisco's Chinatown. It was the first plague epidemic in the continental United States. The epidemic was recognized by medical authorities in March 1900, but its existence was denied for more than two years by California's Republican governor Henry Gage. His denial was based on business reasons, to protect the reputations of San Francisco and California and to prevent the loss of revenue due to quarantine. The failure to act quickly may have allowed the disease to establish itself among local animal populations. Federal authorities worked to prove that there was a major health problem, and they isolated the affected area; this undermined Gage's credibility, and he lost the governorship in the 1902 elections. The new governor, George Pardee, implemented public-health measures and the epidemic was stopped in 1904. There were 121 cases identified, resulting in 119 deaths.
An Ebola virus epidemic in Sierra Leone occurred in 2014, along with the neighbouring countries of Guinea and Liberia. At the time it was discovered, it was thought that Ebola virus was not endemic to Sierra Leone or to the West African region and that the epidemic represented the first time the virus was discovered there. However, US researchers pointed to lab samples used for Lassa fever testing to suggest that Ebola had been in Sierra Leone as early as 2006.
Patient Zero is a 2018 science fiction horror film directed by Stefan Ruzowitzky and written by Mike Le. The film stars Matt Smith, Natalie Dormer, John Bradley, Stanley Tucci, Agyness Deyn, and Clive Standen. The plot involves a group of survivors who set out to find an antidote for a highly contagious virus that turns the infected into a ravenous but highly intelligent new species.
"Aftershocks" is the eleventh episode of the second season of the American television series Agents of S.H.I.E.L.D. Based on the Marvel Comics organization S.H.I.E.L.D., it follows Phil Coulson and his team of S.H.I.E.L.D. agents as they race to strike back against Hydra after an apparent defeat to the latter, while several characters discover they have gained new abilities following the end of the previous episode. It is set in the Marvel Cinematic Universe (MCU) and acknowledges the franchise's films. The episode was written by Maurissa Tancharoen and Jed Whedon, and directed by Billy Gierhart.
On 31 December 2019, China announced the discovery of a cluster of pneumonia cases in Wuhan. The first Danish case was reported on 27 February, and prime minister Mette Frederiksen announced lockdown measures on 11 March effective from 13 March. Following a period of consistent increases in hospitalisations, the number of people in hospital with COVID-19 fell from March onwards, with the number of cases in need of intensive care and ventilator units, also peaking in late March. Starting on 15 April, a very slow and gradual reopening was initiated.
The Superdeep is a 2020 Russian horror film directed by Arseny Syuhin, based on the real-life Kola Superdeep Borehole.
The Baker family consists of fictional characters featured in Capcom's Resident Evil video game series. First appearing in Resident Evil 7: Biohazard, its main family members are a nuclear family consisting of married couple Jack and Marguerite and their two adult children, Lucas and Zoe. Inspired by characters from seminal films in horror cinema such as The Shining, The Evil Dead, and The Texas Chain Saw Massacre, the Bakers reside within their bayou estate in the fictional parish of Dulvey, Louisiana in the United States. Within the game's narrative, they are under the influence of Eveline, a biologically engineered being who "adopted" herself into the Baker family, granting the family superhuman powers at the expense of twisting most of them into insane and murderous individuals prior to the events of Resident Evil 7, with the exception of Zoe who retains a benevolent personality. The 2017 Resident Evil 7: End of Zoe DLC features Joe Baker, a member from the extended family who is unaffected by Eveline, as its protagonist.
This page is based on this Wikipedia article Text is available under the CC BY-SA 4.0 license; additional terms may apply. Images, videos and audio are available under their respective licenses.
