YY1AP1

YY1AP1
Identifiers
Aliases	YY1AP1 , HCCA1, HCCA2, YAP, YY1AP, YY1 associated protein 1, GRNG
External IDs	OMIM: 607860 HomoloGene: 130398 GeneCards: YY1AP1
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q22 Start 155,659,443 bp [1] End 155,689,000 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon oocyte secondary oocyte blood corpus callosum gastrocnemius muscle saphenous vein nipple spongy bone superficial temporal artery n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytoplasm nucleus fibrillar center Ino80 complex nucleoplasm nucleolus Biological process regulation of transcription, DNA-templated transcription, DNA-templated cell differentiation regulation of cell cycle cell population proliferation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55249 n/a Ensembl ENSG00000163374 n/a UniProt Q9H869 n/a RefSeq (mRNA) NM_001198899 NM_001198900 NM_001198901 NM_001198902 NM_001198903 NM_001198904 NM_001198905 NM_001198906 NM_018253 NM_139118 NM_139119 NM_139120 NM_139121 n/a RefSeq (protein) NP_001185828 NP_001185829 NP_001185830 NP_001185831 NP_001185832 NP_001185833 NP_001185834 NP_001185835 NP_060723 NP_620829 NP_620830 NP_620832 n/a Location (UCSC) Chr 1: 155.66 – 155.69 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

YY1-associated protein 1 is a protein that in humans is encoded by the YY1AP1 gene. ^{[3] [4]}

The encoded gene product presumably interacts with YY1 protein; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms. ^[4]

References

1. GRCh38: Ensembl release 89: ENSG00000163374 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Wang ZX, Wang HY, Wu MC (Nov 2001). "Identification and characterization of a novel human hepatocellular carcinoma-associated gene". Br J Cancer. 85 (8): 1162–7. doi:10.1054/bjoc.2001.2059. PMC   2375167 . PMID   11710830.
4. "Entrez Gene: YY1AP1 YY1 associated protein 1".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Wang Z, Hu G, Wang H, Wu M (2002). "[Clone of a novel liver cancer associated gene and analysis of the secondary structures of the predicted protein]". Zhonghua Gan Zang Bing Za Zhi. 10 (1): 25–7. PMID   11856496.
• Zeng JZ, Wang HY, Chen ZJ, et al. (2002). "Molecular cloning and characterization of a novel gene which is highly expressed in hepatocellular carcinoma". Oncogene. 21 (32): 4932–43. doi:10.1038/sj.onc.1205652. PMID   12118372. S2CID   30899427.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Wang CY, Liang YJ, Lin YS, et al. (2004). "YY1AP, a novel co-activator of YY1". J. Biol. Chem. 279 (17): 17750–5. doi: 10.1074/jbc.M310532200 . PMID   14744866.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC   514446 . PMID   15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.
• Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi: 10.1016/j.cell.2006.03.032 . PMID   16713569. S2CID   13709685.