ZDHHC3

ZDHHC3
Identifiers
Aliases	ZDHHC3 , DHHC-3, GODZ, ZNF373, zinc finger DHHC-type containing 3, DHHC3, zinc finger DHHC-type palmitoyltransferase 3
External IDs	OMIM: 617150 MGI: 1926134 HomoloGene: 9582 GeneCards: ZDHHC3
Gene location (Human) Chr. Chromosome 3 (human) [1] Band 3p21.31 Start 44,915,257 bp [1] End 44,976,185 bp [1]
Gene location (Mouse) Chr. Chromosome 9 (mouse) [2] Band 9|9 F4 Start 123,066,160 bp [2] End 123,113,205 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in rectum stromal cell of endometrium Left adrenal gland Right adrenal gland sperm skin of abdomen gallbladder upper lobe of left lung right lung popliteal artery Top expressed in lip pontine nuclei left lung dorsal tegmental nucleus yolk sac cerebellar cortex right lung lobe superior frontal gyrus medial vestibular nucleus stomach More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein-cysteine S-palmitoyltransferase activity palmitoyltransferase activity transferase activity acyltransferase activity Cellular component integral component of membrane Golgi membrane Golgi apparatus membrane endoplasmic reticulum Biological process protein targeting protein palmitoylation protein targeting to membrane peptidyl-L-cysteine S-palmitoylation localization within membrane protein localization to photoreceptor outer segment Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51304 69035 Ensembl ENSG00000163812 ENSMUSG00000025786 UniProt Q9NYG2 Q8R173 RefSeq (mRNA) NM_001135179 NM_001135180 NM_016598 NM_001330761 NM_001349376 NM_001349377 NM_001349378 NM_001349379 NM_001349380 NM_001349381 NM_026917 RefSeq (protein) NP_001128651 NP_001317690 NP_057682 NP_001336305 NP_001336306 NP_001336307 NP_001336308 NP_001336309 NP_001336310 NP_081193 NP_001359467 NP_001359468 NP_001359469 NP_001359470 NP_001359471 NP_001359472 NP_001359473 NP_001359475 NP_001359476 NP_001359477 NP_001359478 NP_001359479 NP_001359480 NP_001359481 NP_001359482 Location (UCSC) Chr 3: 44.92 – 44.98 Mb Chr 9: 123.07 – 123.11 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Palmitoyltransferase ZDHHC3 is an enzyme that in humans is encoded by the ZDHHC3 gene that contains a DHHC domain. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000163812 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000025786 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: ZDHHC3 zinc finger, DHHC-type containing 3".

Further reading

• Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi: 10.1016/j.cell.2006.03.032 . PMID   16713569. S2CID   13709685.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC   442148 . PMID   15231748.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Uemura T, Mori H, Mishina M (2002). "Isolation and characterization of Golgi apparatus-specific GODZ with the DHHC zinc finger domain". Biochem. Biophys. Res. Commun. 296 (2): 492–6. doi:10.1016/S0006-291X(02)00900-2. PMID   12163046.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC   139146 . PMID   9110174.
• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID   8619474.