ZNF16

ZNF16
Identifiers
Aliases	ZNF16 , HZF1, KOX9, zinc finger protein 16
External IDs	OMIM: 601262 HomoloGene: 56008 GeneCards: ZNF16
Gene location (Human) Chr. Chromosome 8 (human) [1] Band 8q24.3 Start 144,930,358 bp [1] End 144,950,888 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte ganglionic eminence gastrocnemius muscle secondary oocyte skin of abdomen stromal cell of endometrium body of pancreas metanephric glomerulus gallbladder endothelial cell n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding protein binding metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus nucleolus Biological process positive regulation of cell cycle phase transition positive regulation of kinase activity cell cycle negative regulation of apoptotic process regulation of transcription, DNA-templated positive regulation of megakaryocyte differentiation positive regulation of cell division positive regulation of erythrocyte differentiation transcription, DNA-templated positive regulation of cell population proliferation cellular response to sodium dodecyl sulfate cell division regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7564 n/a Ensembl ENSG00000170631 n/a UniProt P17020 n/a RefSeq (mRNA) NM_001029976 NM_006958 n/a RefSeq (protein) NP_001025147 NP_008889 n/a Location (UCSC) Chr 8: 144.93 – 144.95 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Zinc finger protein 16 is a protein that in humans is encoded by the ZNF16 gene. ^[3]

The protein encoded by this gene contains a C2H2 type of zinc finger, and thus may function as a transcription factor. This gene is located in a region close to ZNF7/KOX4, a gene also encoding a zinc finger protein, on chromosome 8. Two alternatively spliced variants, encoding the same protein, have been identified. ^[3]

References

1. GRCh38: Ensembl release 89: ENSG00000170631 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: ZNF16 zinc finger protein 16".

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Dreier B, Segal DJ, Barbas CF (2000). "Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains". J. Mol. Biol. 303 (4): 489–502. doi:10.1006/jmbi.2000.4133. PMID   11054286.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Rousseau-Merck MF, Duro D, Berger R, Thiesen HJ (1995). "Chromosomal localization of two KOX zinc finger genes on chromosome bands 7q21-q22". Ann. Genet. 38 (2): 81–4. PMID   7486829.
• Thiesen HJ (1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–74. PMID   2288909.