Zhankuic acid

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Zhankuic acids are sterols isolated from the fungus Taiwanofungus camphoratus . [1] Zhankuic acid C possesses in vitro anti-inflammatory properties due to its role as a selective TLR4/MD-2 antagonist. [2]

References

  1. ↑ Lin, Ming-Kuem; Lee, Meng-Shiou; Chang, Wen-Te; Chen, Hsing-Yu; Chen, Jin-Fu; Li, Yi-Rong; Lin, Chi-Chen; Wu, Tian-Shung (2015). "Immunosuppressive effect of zhankuic acid C from Taiwanofungus camphoratus on dendritic cell activation and the contact hypersensitivity response". Bioorganic & Medicinal Chemistry Letters. 25 (20): 4637–4641. doi:10.1016/j.bmcl.2015.08.038. PMID   26338360.
  2. ↑ Chen, Y.-F; Shiau, A.-L; Wang, S.-H; Yang, J.-S; Chang, S.-J; Wu, C.-L; Wu, T.-S (2014). "Zhankuic Acid A Isolated from Taiwanofungus camphoratus Is a Novel Selective TLR4/MD-2 Antagonist with Anti-Inflammatory Properties". The Journal of Immunology. 192 (6): 2778–2786. doi:10.4049/jimmunol.1301931. PMC   3948111 . PMID   24532584.
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