Evan Flatow

Last updated
Evan Flatow
Born (1956-03-21) March 21, 1956 (age 67)
Nationality American
Alma mater Princeton University, Columbia University College of Physicians and Surgeons
Known for shoulder surgery, scientist, researcher
AwardsThe Neer Award for Excellence in Shoulder Research, American Shoulder and Elbow Surgeons, 1992, 1994, 1996, 2004

Lifetime Achievement Award, New York Chapter, Arthritis Foundation, 2009

Elected to College of Fellows, American Institute for Medical and Biological Engineering, 2010

Contents

Scientific career
Fields orthopaedic surgeon
InstitutionsPresident, Mount Sinai West

Evan Flatow (born March 21, 1956) is an American orthopaedic surgeon-scientist. As of 2023, he is President of Mount Sinai West (formerly Mount Sinai Roosevelt), part of the Mount Sinai Health System. He published more than 400 book chapters and peer-reviewed articles. [1] [2] Flatow is indicated as principal or co-principal investigator for nine research grants and listed on six patents for influential shoulder implant systems. [3] [4]

Before Flatow's appointment at Mount Sinai West, he served as the Bernard J. Lasker Professor and Chair of the Leni and Peter W. May Department of Orthopaedic Surgery at Icahn School of Medicine at Mount Sinai, where he established a basic science tendon research group in the Orthopaedic Research Laboratory, and he also served as Director of the Orthopaedic Surgery Service at Mount Sinai Hospital in New York City. [5] He was chosen by Castle Connolly as one of America's top doctors [6] and has won the American Shoulder and Elbow Surgeons' Neer Award, its highest honor, four times. [7] [8] He is the President of the Board of Trustees of St. Hilda's & St. Hugh's, where he graduated in 1973.

Career

Flatow graduated from Princeton University with an A.B. in biomedical sciences in 1977 after completing a 39-page long senior thesis titled "The Comparative Biochemistry of Microtubule Accessory Proteins." [9] He earned his medical degree from the Columbia University College of Physicians and Surgeons in 1981 and completed a surgical residency at St. Luke's-Roosevelt Hospital Center and an orthopaedic residency and fellowship at Columbia-Presbyterian Medical Center. [8]

In 1998, after 11 years on the faculty at Columbia University, Flatow joined the staff at Mount Sinai Hospital. He was Chair of Orthopaedics from 2005 until 2014, and then President of Mount Sinai West, a position he still holds as of 2023. In collaboration with Mount Sinai's Department of Anesthesiology, Flatow pioneered the use of regional blocks to diminish the need for general anesthesia in shoulder surgery. [5] [8]

He held positions as Chair of the Trustees of the Journal of Shoulder and Elbow Surgery, and Chair of the Publications Committee and of the Council on Education of the American Academy of Orthopaedic Surgeons. [10] [11] He also served as President of American Shoulder & Elbow Surgeons. [12]

Scientific contributions

Grants

As of 2023, Flatow was Principal Investigator (PI) or Co-Principal on 11 research grants. Partial list:

Patents

Flatow co-developed humeral stem and glenoid socket designs and procedures for coated and uncoated shoulder replacements. The process requires minimal bone resection and as of 2023 is used globally [11] in total shoulder arthroplasty. [16] [17] Patents include:

Developments and implications

Flatow focuses on minimally invasive fracture repair, arthroscopic rotator cuff surgery, arthroscopic repair and shoulder replacement. [24] Developments include:

Shoulder articular geometry and kinematics: Flatow contributed to the development of a glenoid implant with dual-curvatures allowing central conformity with low contact stress. [25]

Cadaver studies of rotator cuff tendon injury: demonstrated the effects of subacromial compression and tensile load on the supraspinatus tendon, with implications for clinical failure. [26] [27] [28]

Clinical outcome studies of rotator cuff tendon repair: rotator cuff tendon failure and repair, demonstration that cuff-tendon repair was a cost-effective procedure, that re-tears were common, and that muscle atrophy did not recover after tendon repair. [29]

Development of a rat infrapatellar tendon repetitive fatigue-damage model of tendon injury: collaborated to refine histologic and imaging techniques to assess tendon damage. [30] [31] [32]

Characterization of the mechanical and biologic response of tendon to repetitive fatigue damage, and the effect of exercise.Demonstrated that damage is permanent, apoptosis resulted, and fatigued tendon failed to mount a robust biologic and reparative response. [33] [34] [35]

Honors and awards

Publications

Flatow is a reviewer for Clinical Orthopaedics and Related Research, the Journal of Bone and Joint Surgery, Arthroscopy, the Journal of Orthopaedic Research, and the American Journal of Sports Medicine. He is the former North American editor and chair, board of trustees, for the Journal of Shoulder and Elbow Surgery. He is a reviewer for that journal as of 2022.

Books

Peer reviewed publications

As of 2023, Flatow was cited 22,600 times, has an h-index of 81and an i10-index of 194. [36]

Highest cited (partial list):

Most recent:

Related Research Articles

<span class="mw-page-title-main">Rotator cuff</span> Group of muscles

The rotator cuff is a group of muscles and their tendons that act to stabilize the human shoulder and allow for its extensive range of motion. Of the seven scapulohumeral muscles, four make up the rotator cuff. The four muscles are:

<span class="mw-page-title-main">Shoulder problem</span> Medical condition

Shoulder problems including pain, are one of the more common reasons for physician visits for musculoskeletal symptoms. The shoulder is the most movable joint in the body. However, it is an unstable joint because of the range of motion allowed. This instability increases the likelihood of joint injury, often leading to a degenerative process in which tissues break down and no longer function well.

<span class="mw-page-title-main">Shoulder</span> Part of the body

The human shoulder is made up of three bones: the clavicle (collarbone), the scapula, and the humerus as well as associated muscles, ligaments and tendons.

<span class="mw-page-title-main">Orthopedic surgery</span> Branch of surgery concerned with the musculoskeletal and bones system

Orthopedic surgery or orthopedics is the branch of surgery concerned with conditions involving the musculoskeletal system. Orthopedic surgeons use both surgical and nonsurgical means to treat musculoskeletal trauma, spine diseases, sports injuries, degenerative diseases, infections, tumors, and congenital disorders.

<span class="mw-page-title-main">Rotator cuff tear</span> Medical condition

Rotator cuff tendinopathy is a process of senescence. The pathophysiology is mucoid degeneration. Most people develop rotator cuff tendinopathy within their lifetime.

<span class="mw-page-title-main">Adhesive capsulitis of the shoulder</span> Painful disease restricting movement

Adhesive capsulitis, also known as frozen shoulder, is a condition associated with shoulder pain and stiffness. It is a common shoulder ailment that is marked by pain and a loss of range of motion, particularly in external rotation. There is a loss of the ability to move the shoulder, both voluntarily and by others, in multiple directions. The shoulder itself, however, does not generally hurt significantly when touched. Muscle loss around the shoulder may also occur. Onset is gradual over weeks to months. Complications can include fracture of the humerus or biceps tendon rupture.

<span class="mw-page-title-main">Joint replacement</span> Orthopedic surgery to replace a joint

Joint replacement is a procedure of orthopedic surgery known also as arthroplasty, in which an arthritic or dysfunctional joint surface is replaced with an orthopedic prosthesis. Joint replacement is considered as a treatment when severe joint pain or dysfunction is not alleviated by less-invasive therapies. Joint replacement surgery is often indicated from various joint diseases, including osteoarthritis and rheumatoid arthritis.

<span class="mw-page-title-main">SLAP tear</span> Medical condition

A SLAP tear or SLAP lesion is an injury to the glenoid labrum. SLAP is an acronym for "superior labral tear from anterior to posterior".

Cold compression therapy, also known as hilotherapy, combines two of the principles of rest, ice, compression, elevation to reduce pain and swelling from a sports or activity injury to soft tissues and is recommended by orthopedic surgeons following surgery. The therapy is especially useful for sprains, strains, pulled muscles and pulled ligaments.

<span class="mw-page-title-main">Subacromial bursitis</span> Medical condition

Subacromial bursitis is a condition caused by inflammation of the bursa that separates the superior surface of the supraspinatus tendon from the overlying coraco-acromial ligament, acromion, and coracoid and from the deep surface of the deltoid muscle. The subacromial bursa helps the motion of the supraspinatus tendon of the rotator cuff in activities such as overhead work.

<span class="mw-page-title-main">Shoulder replacement</span>

Shoulder replacement is a surgical procedure in which all or part of the glenohumeral joint is replaced by a prosthetic implant. Such joint replacement surgery generally is conducted to relieve arthritis pain or fix severe physical joint damage.

<span class="mw-page-title-main">Shoulder impingement syndrome</span> Medical condition

Shoulder impingement syndrome is a syndrome involving tendonitis of the rotator cuff muscles as they pass through the subacromial space, the passage beneath the acromion. It is particularly associated with tendonitis of the supraspinatus muscle. This can result in pain, weakness, and loss of movement at the shoulder.

<span class="mw-page-title-main">Platelet-rich plasma</span> Blood product used in transfusion medicine

Platelet-rich plasma (PRP), also known as autologous conditioned plasma, is a concentrate of platelet-rich plasma protein derived from whole blood, centrifuged to remove red blood cells. Though promoted to treat an array of medical problems, evidence for benefit is mixed as of 2020, with some evidence for use in certain conditions and against use in other conditions.

Michael J. Bronson, M.D., is an American orthopaedic surgeon, Chairman of the Department of Orthopedic Surgery, Mount Sinai West and Mount Sinai Morningside, and Chief of Joint Replacement Surgery at the Icahn School of Medicine at Mount Sinai in New York, and the author of extensive advances in the development of minimally invasive surgical instruments to advance unicondylar partial knee replacement, including the Vision Total Hip System, a widely used hip replacement system that avoids the use of cement.

Joseph D. Zuckerman is an American orthopedic surgeon specializing in shoulder, hip and knee replacement surgery.

Bryan L. Reuss is an American orthopaedic surgeon. He received a Bachelor of Arts Degree in Biology with distinction from the University of Kansas in 1996 and graduated with honors with an M.D. from the University of Nebraska College of Medicine in 2000. From 2000 to 2005, Dr. Reuss was an Orthopaedic Surgery Resident Physician in the Orlando Regional Healthcare System. In 2004-2005 he was awarded the "Resident of the Year" for Orlando Regional Healthcare chosen from all the hospital system's Resident Doctors. He completed an Orthopaedic Fellowship at the University of Cincinnati/Wellington Orthopaedics and Sports Medicine Fellowship in 2006. In 2010, Dr. Reuss was awarded the Sports Medicine Person of the Year from the Athletic Trainers Association of Florida.

<span class="mw-page-title-main">Postarthroscopic glenohumeral chondrolysis</span> Medical condition

Postarthroscopic glenohumeral chondrolysis (PAGCL) is a rare complication of arthroscopic surgery and involves chondrolysis wherein the articular cartilage of the shoulder undergoes rapid, degenerative changes shortly after arthroscopic surgery.

<span class="mw-page-title-main">Reverse shoulder replacement</span>

Reverse shoulder replacement is a type of shoulder replacement in which the normal ball and socket relationship of glenohumeral joint is reversed, creating a more stable joint with a fixed fulcrum. This form of shoulder replacement is utilized in situations in which conventional shoulder replacement surgery would lead to poor outcomes and high failure rates.

<span class="mw-page-title-main">Biceps tendon rupture</span> Complete or partial rupture of a tendon of the biceps brachii muscle

A biceps tendon rupture or bicep tear is a complete or partial rupture of a tendon of the biceps brachii muscle. It can affect any of the three biceps brachii tendons - the proximal tendon of the short head of the muscle belly, the proximal tendon of the long head of the muscle belly, or the distal tendon. The characteristic finding of a biceps tendon rupture is the Popeye sign. Patients often report an audible pop at the time of injury as well as pain, bruising, and swelling. Provocative physical exam maneuvers to assess for a rupture include Ludington's test, Hook test, and the Ruland biceps squeeze test. Treatment and prognosis are highly dependent on the site of the injury described in further detail below.

The Eden-Lange procedure is an orthopedic procedure to alleviate the symptoms of trapezius palsy when more conservative measures, such as spontaneous resolution and surgical nerve repair are not promising. The rhomboid major, rhomboid minor, and levator scapulae muscles are transferred laterally along the scapula to replace the functions of the lower, middle, and upper fibers of the trapezius, respectively. The transferred muscles hold the scapula in a more medial and upwardly rotated position, without winging.

References

  1. "Flatow EL - Search Results - PubMed". PubMed. Retrieved 2022-01-26.
  2. "Evan Flatow". scholar.google.com. Retrieved 2023-02-12.
  3. "A century of shoulder arthroplasty innovations and discoveries". www.healio.com. Retrieved 2022-02-04.
  4. Flatow, E.; Harrison, A. (2011). "A History of Reverse Total Shoulder Arthroplasty". Clinical Orthopaedics and Related Research. 469 (9): 2432–2439. doi:10.1007/s11999-010-1733-6. PMC   3148354 . PMID   21213090. S2CID   33062066.
  5. 1 2 "Mount Sinai Hospital – Doctor profile". Mount Sinai Hospital.
  6. "Castle Connolly Medical Ltd". Archived from the original on June 30, 2009. Retrieved January 17, 2010.
  7. "American Shoulder and Elbow Surgeons". Becker's Hospital Review. Archived from the original on October 22, 2007. Retrieved January 17, 2010.
  8. 1 2 3 "Ten Shoulder Specialists to Know: Becker's Hospital Review". Archived from the original on June 30, 2009. Retrieved January 17, 2010.
  9. Flatow, Evan Lloyd (1977). "The Comparative Biochemistry of Microtubule Accessory Proteins".{{cite journal}}: Cite journal requires |journal= (help)
  10. "AAOS Media Center". www.aaos-annualmeeting-presskit.org. Retrieved 2023-02-13.
  11. 1 2 "LEADERS Interview with Evan L. Flatow, MD, President, Mount Sinai West". www.leadersmag.com. Retrieved 2023-02-13.
  12. "The Top 28 North American Shoulder Surgeons" (PDF). Orthopedics This Week. September 24, 2013. Retrieved February 12, 2023.
  13. Blevins, F. T.; Djurasovic, M.; Flatow, E. L.; Vogel, K. G. (1997). "Biology of the rotator cuff tendon". The Orthopedic Clinics of North America. 28 (1): 1–16. doi:10.1016/s0030-5898(05)70260-1. ISSN   0030-5898. PMID   9024427.
  14. "RePORT ⟩ RePORTER". reporter.nih.gov. Retrieved 2023-02-13.
  15. Klein, Kristine (2022-08-25). "NYCEDC announces $26.6 million grant for two new life sciences facilities". The Architect’s Newspaper. Retrieved 2023-02-12.
  16. Godenèche, Arnaud; Garret, Jérôme; Barth, Johannes; Michelet, Aude; Geais, Laurent (2019-02-20). "Comparison of revision rates and radiographic observations of long and short, uncoated and coated humeral stem designs in total shoulder arthroplasty". EFORT Open Reviews. 4 (2): 70–76. doi:10.1302/2058-5241.4.180046. ISSN   2058-5241. PMC   6404789 . PMID   30931151.
  17. David M. Levy, MD, Joshua A. Metzl, MD, G. Christian Vorys, MD, William N. Levine, MD, Christopher S. Ahmad, MD, and Louis U. Bigliani, MD. "Clinical and Radiographic Outcomes of Total Shoulder Arthroplasty With a Hybrid Dual-Radii Glenoid Component" (PDF). American Journal of Orthopedics. Retrieved February 15, 2023.{{cite web}}: CS1 maint: multiple names: authors list (link)
  18. US 5928285,Bigliani, Louis U.; Flatow, Evan L.& Norman, Delfreda L.,"Orthopaedic implant having an articulating surface with a conforming and translational surface",published 1999-07-27, assigned to Bristol-Meyers Squibb Co.
  19. US 5928285,Bigliani, Louis U.; Flatow, Evan L.& Norman, Delfreda L.,"Orthopaedic implant having an articulating surface with a conforming and translational surface",published 1999-07-27, assigned to Bristol-Meyers Squibb Co.
  20. US 6017306,Bigliani, Louis U.; Flatow, Evan L.& Norman, Delfreda L.et al.,"Clamp assembly for use with orthopaedic retractor frame assembly",published 2000-01-25, assigned to Bristol-Meyers Squibb Co.
  21. US 6120507,Allard, Randall N.; Willard, David B.& Flatow, Evan L.,"Instrument and method for seating prosthesis",published 2000-09-19, assigned to Bristol-Meyers Squibb Co.
  22. US 7699853,Durand-Allen, Anitra; Wiley, Roy& Bigliani, Louiset al.,"Method and instruments for positioning humeral component during shoulder arthroplasty",published 2010-04-20, assigned to Zimmer Inc.
  23. US 10874748,Sun, Hui B.; Flatow, Evan L.& Wanich, Tonyet al.,"Intervention for tendinopathy",published 2020-12-29, assigned to Albert Einstein College of Medicine,and Icahn School of Medicine at Mount Sinai & Montefiore Medical Center
  24. Keenan, John (2018-06-06). "Orthopaedic resident graduation events Friday". Newsroom. Retrieved 2023-02-12.
  25. Ehresmann, K R; Mills, W A; Loewenson, P R; Moore, K A (2000). "Attitudes and practices regarding varicella vaccination among physicians in Minnesota: implications for public health and provider education". American Journal of Public Health. 90 (12): 1917–1920. doi:10.2105/ajph.90.12.1917. ISSN   0090-0036. PMC   1446435 . PMID   11111266.
  26. Flatow, E. L.; Soslowsky, L. J.; Ticker, J. B.; Pawluk, R. J.; Hepler, M.; Ark, J.; Mow, V. C.; Bigliani, L. U. (1994). "Excursion of the rotator cuff under the acromion. Patterns of subacromial contact". The American Journal of Sports Medicine. 22 (6): 779–788. doi:10.1177/036354659402200609. hdl: 2027.42/67283 . ISSN   0363-5465. PMID   7856802. S2CID   11577634.
  27. Huang, Chun-Yuh; Wang, Vincent M.; Pawluk, Robert J.; Bucchieri, John S.; Levine, William N.; Bigliani, Louis U.; Mow, Van C.; Flatow, Evan L. (2005). "Inhomogeneous mechanical behavior of the human supraspinatus tendon under uniaxial loading". Journal of Orthopaedic Research. 23 (4): 924–930. doi: 10.1016/j.orthres.2004.02.016 . ISSN   0736-0266. PMID   16023009. S2CID   12121653.
  28. Huang, Chun-Yuh; Wang, Vincent M.; Flatow, Evan L.; Mow, Van C. (2009-03-11). "Temperature-dependent viscoelastic properties of the human supraspinatus tendon". Journal of Biomechanics. 42 (4): 546–549. doi:10.1016/j.jbiomech.2008.11.013. ISSN   1873-2380. PMC   2684675 . PMID   19159888.
  29. Bishop, Julie; Klepps, Steven; Lo, Ian K.; Bird, Justin; Gladstone, James N.; Flatow, Evan L. (2006). "Cuff integrity after arthroscopic versus open rotator cuff repair: a prospective study". Journal of Shoulder and Elbow Surgery. 15 (3): 290–299. doi:10.1016/j.jse.2005.09.017. ISSN   1058-2746. PMID   16679227.
  30. Laudier, Damien; Schaffler, Mitchell B.; Flatow, Evan L.; Wang, Vincent M. (2007). "Novel procedure for high-fidelity tendon histology". Journal of Orthopaedic Research. 25 (3): 390–395. doi: 10.1002/jor.20304 . ISSN   0736-0266. PMID   17149746. S2CID   21816985.
  31. Fung, David T.; Wang, Vincent M.; Andarawis-Puri, Nelly; Basta-Pljakic, Jelena; Li, Yonghui; Laudier, Damien M.; Sun, Hui B.; Jepsen, Karl J.; Schaffler, Mitchell B.; Flatow, Evan L. (2010-01-19). "Early response to tendon fatigue damage accumulation in a novel in vivo model". Journal of Biomechanics. 43 (2): 274–279. doi:10.1016/j.jbiomech.2009.08.039. ISSN   1873-2380. PMC   3366582 . PMID   19939387.
  32. Fung, David T.; Sereysky, Jedd B.; Basta-Pljakic, Jelena; Laudier, Damien M.; Huq, Rumana; Jepsen, Karl J.; Schaffler, Mitchell B.; Flatow, Evan L. (2010). "Second harmonic generation imaging and Fourier transform spectral analysis reveal damage in fatigue-loaded tendons". Annals of Biomedical Engineering. 38 (5): 1741–1751. doi:10.1007/s10439-010-9976-7. ISSN   1573-9686. PMC   4785269 . PMID   20232150.
  33. Sun, Hui B.; Andarawis-Puri, Nelly; Li, Yonghui; Fung, David T.; Lee, Jonathan Y.; Wang, Vincent M.; Basta-Pljakic, Jelena; Leong, Daniel J.; Sereysky, Jedd B.; Ros, Stephen J.; Klug, Raymond A. (2010). "Cycle-dependent matrix remodeling gene expression response in fatigue-loaded rat patellar tendons". Journal of Orthopaedic Research. 28 (10): 1380–1386. doi:10.1002/jor.21132. ISSN   1554-527X. PMC   4408775 . PMID   20839322.
  34. Andarawis-Puri, Nelly; Sereysky, Jedd B.; Jepsen, Karl J.; Flatow, Evan L. (2012-01-03). "The relationships between cyclic fatigue loading, changes in initial mechanical properties, and the in vivo temporal mechanical response of the rat patellar tendon". Journal of Biomechanics. 45 (1): 59–65. doi:10.1016/j.jbiomech.2011.10.008. ISSN   1873-2380. PMC   3763928 . PMID   22055428.
  35. Andarawis-Puri, Nelly; Philip, Anaya; Laudier, Damien; Schaffler, Mitchell B.; Flatow, Evan L. (2014). "Temporal effect of in vivo tendon fatigue loading on the apoptotic response explained in the context of number of fatigue loading cycles and initial damage parameters". Journal of Orthopaedic Research. 32 (9): 1097–1103. doi:10.1002/jor.22639. ISSN   1554-527X. PMC   4209741 . PMID   24838769.
  36. "Evan Flatow". scholar.google.com. Retrieved 2022-01-26.
  37. "Fatty infiltration and atrophy of the rotator cuff do not improve after rotator cuff repair and correlate with poor functional outcome". scholar.google.com. Retrieved 2023-02-13.
  38. "Excursion of the rotator cuff under the acromion: patterns of subacromial contact". scholar.google.com. Retrieved 2023-02-13.
  39. White, Christopher A.; Duey, Akiro; Parsons, Bradford O.; Flatow, Evan L.; Cagle, Paul J. (2023-06-01). "Anatomic total shoulder arthroplasty outcomes and implant survivability at greater than 22 years postoperative follow-up: A case series". Journal of Orthopaedic Reports. 2 (2): 100129. doi: 10.1016/j.jorep.2022.100129 . ISSN   2773-157X. S2CID   255636585.