Haplogroup CT

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Haplogroup CT
Y-DNA tree.svg
Possible time of originc. 70,000 years ago, [1] ca. 100,000 years ago, [2] or about 101,000 years ago [3]
Possible place of origin Africa, [4] [5] [6] [2] possibly Northeast Africa [7]
Ancestor Haplogroup BT
Descendants Haplogroup CF, Haplogroup DE
Defining mutationsP9.1, M168, M294, V9, V41, V54, V189, and V226

Haplogroup CT is a human Y chromosome haplogroup, defining one of the major paternal lineages of humanity.

Contents

Men who carry the CT clade have Y chromosomes with the SNP mutation M168, along with P9.1 and M294. These mutations are present in all modern human male lineages except A and B-M60, which are both found almost exclusively in Africa.

The most recent common male line ancestor (TMRCA) of all CT men today probably predated the recent African origin of modern humans, a migration in which some of his descendants participated. He is therefore thought to have lived in Africa before this proposed migration. [1] [5] [4] In keeping with the concept of "Y-chromosomal Adam" given to the patrilineal ancestor of all living humans, CT-M168 has therefore also been referred to in popularized accounts as being the lineage of "Eurasian Adam" or "Out of Africa Adam"; because, along with many African Y-lineages, all non-African Y-lineages descend from it. [8] [7] [6]

No male in paragroup CT* has ever been discovered in modern populations. This means that all males carrying this haplogroup are also defined as being in one of the several major branch clades. All known surviving descendant lineages of CT are in one of two major subclades, CF and DE. In turn, DE is divided into a predominantly Asia-distributed haplogroup D-CTS3946 and a predominantly Africa-distributed haplogroup E-M96, while CF is divided into an East Asian, Native American, and Oceanian haplogroup C-M130 and haplogroup F-M89, which dominates most non-African populations. [6]

Subclades

Haplogroup CT (M168/PF1416)

Sources

See also

Genetics

Y-DNA C subclades

Related Research Articles

<span class="mw-page-title-main">Haplogroup</span> Group of similar haplotypes

A haplotype is a group of alleles in an organism that are inherited together from a single parent, and a haplogroup is a group of similar haplotypes that share a common ancestor with a single-nucleotide polymorphism mutation. More specifically, a haplogroup is a combination of alleles at different chromosomal regions that are closely linked and that tend to be inherited together. As a haplogroup consists of similar haplotypes, it is usually possible to predict a haplogroup from haplotypes. Haplogroups pertain to a single line of descent. As such, membership of a haplogroup, by any individual, relies on a relatively small proportion of the genetic material possessed by that individual.

<span class="mw-page-title-main">Haplogroup C-M130</span> Human Y chromosome DNA grouping found primarily in Asia

Haplogroup C is a major Y-chromosome haplogroup, defined by UEPs M130/RPS4Y711, P184, P255, and P260, which are all SNP mutations. It is one of two primary branches of Haplogroup CF alongside Haplogroup F. Haplogroup C is found in ancient populations on every continent except Africa and is the predominant Y-DNA haplogroup among males belonging to many peoples indigenous to East Asia, Central Asia, Siberia, North America and Australia as well as a some populations in Europe, the Levant, and later Japan. The haplogroup is also found with moderate to low frequency among many present-day populations of Southeast Asia, South Asia, and Southwest Asia.

Haplogroup D1 or D-M174 is a subclade of Haplogroup D-CTS3946. This male haplogroup is found primarily in East Asia ,magar ethinic Nepal and the Andaman Islands, though it is also found regularly with low frequency in Central Asia and Mainland Southeast Asia. It's also found as far as Europe and Middle east in lower frequencies.

Haplogroup E-M96 is a human Y-chromosome DNA haplogroup. It is one of the two main branches of the older and ancestral haplogroup DE, the other main branch being haplogroup D. The E-M96 clade is divided into two main subclades: the more common E-P147, and the less common E-M75.

<span class="mw-page-title-main">Haplogroup F-M89</span> Human Y chromosome DNA grouping indicating common ancestry

Haplogroup F, also known as F-M89 and previously as Haplogroup FT is a very common Y-chromosome haplogroup. The clade and its subclades constitute over 90% of paternal lineages outside of Africa.

<span class="mw-page-title-main">Haplogroup M-P256</span> Human Y chromosome DNA grouping common in New Guinea

Haplogroup M, also known as M-P256 and Haplogroup K2b1b is a Y-chromosome DNA haplogroup. M-P256 is a descendant haplogroup of Haplogroup K2b1, and is believed to have first appeared between 32,000 and 47,000 years ago.

<span class="mw-page-title-main">Haplogroup O-M175</span> Haplogroup O. Human Y chromosome DNA grouping common in Asia.

Haplogroup O, also known as O-M175, is a human Y-chromosome DNA haplogroup. It is primarily found among populations in Southeast Asia and East Asia. It also is found in various percentages of populations of the Russian Far East, South Asia, Central Asia, Caucasus, Crimea, Ukraine, Iran, Oceania, Madagascar and the Comoros. Haplogroup O is a primary descendant of haplogroup NO-M214.

<span class="mw-page-title-main">Human Y-chromosome DNA haplogroup</span> Human DNA groupings

In human genetics, a human Y-chromosome DNA haplogroup is a haplogroup defined by mutations in the non-recombining portions of DNA from the male-specific Y chromosome. Many people within a haplogroup share similar numbers of short tandem repeats (STRs) and types of mutations called single-nucleotide polymorphisms (SNPs).

In human genetics, Haplogroup O-M268, also known as O1b, is a Y-chromosome DNA haplogroup. Haplogroup O-M268 is a primary subclade of haplogroup O-F265, itself a primary descendant branch of Haplogroup O-M175.

In human genetics, Haplogroup O-M119 is a Y-chromosome DNA haplogroup. Haplogroup O-M119 is a descendant branch of haplogroup O-F265 also known as O1a, one of two extant primary subclades of Haplogroup O-M175. The same clade previously has been labeled as O-MSY2.2.

<span class="mw-page-title-main">Haplogroup D-M15</span>

Its phylogenetically closest relatives are found among the peoples of Japan, Central Asia, and the Andaman Islands in the Bay of Bengal. It is more distantly related to the Haplogroup D*, whose sub-clades are common throughout Asia.

Haplogroup IJ (M429/P125) is a human Y-chromosome DNA haplogroup, an immediate descendant of Haplogroup IJK. IJK is a branch of Haplogroup HIJK.

Haplogroup K2, also known as K-M526 and formerly known as K(xLT) and MNOPS, is a human Y-DNA haplogroup.

Haplogroup CF, also known as CF-P143 and CT(xDE), is a human Y-chromosome DNA haplogroup. This paternal lineage is defined by the SNP P143. The clade's existence and distribution are inferred from the fact that haplogroups descended from CF include most human male lineages in Eurasia, Oceania and The Americas.

Haplogroup IJK is a human Y-chromosome DNA haplogroup. IJK is a primary branch of the macrohaplogroup HIJK. Its direct descendants are haplogroup IJ and haplogroup K.

E-Z827, also known as E1b1b1b, is a major human Y-chromosome DNA haplogroup. It is the parent lineage to the E-Z830 and E-V257 subclades, and defines their common phylogeny. The former is predominantly found in the Horn of Africa and the Middle East; the latter is most frequently observed in North Africa, with its E-M81 subclade observed among the ancient Guanche natives of the Canary Islands. E-Z827 is also found at lower frequencies in Europe, and in isolated parts of Southeast Africa.

Haplogroup K2b (P331), also known as MPS is a human y-chromosome haplogroup that is thought to be less than 3,000 years younger than K, and less than 10,000 years younger than F, meaning it probably is around 50,000 years old, according to the age estimates of Tatiana Karafet et al. 2014.

HaplogroupGHIJK, defined by the SNPs M3658, F1329, PF2622, and YSC0001299, is a common Y-chromosome haplogroup. This macrohaplogroup and its subclades contain the vast majority of the world's existing male population.

Haplogroup HIJK, defined by the SNPs F929, M578, PF3494 and S6397, is a common Y-chromosome haplogroup. Like its parent macrohaplogroup GHIJK, Haplogroup HIJK and its subclades comprise the vast majority of the world's male population.

<span class="mw-page-title-main">Haplogroup D-CTS3946</span> Human Y-chromosome DNA haplogroup

Haplogroup D or D-CTS3946 is a Y-chromosome haplogroup. Like its relative distant sibling, haplogroup E-M96, D-CTS3946 has the YAP+ unique-event polymorphism, which defines their parent, haplogroup DE.

References

  1. 1 2 Karafet et al. (2008) give "70,000", citing "68,500±6000 years" from Hammer and Zegura (2002). Karafet TM, Mendez FL, Meilerman MB, Underhill PA, Zegura SL, Hammer MF (2008). "New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree". Genome Research. 18 (5): 830–8. doi:10.1101/gr.7172008. PMC   2336805 . PMID   18385274.. The split between CF and DE (which in the absence of a paragroup CT* is equivalent to the age of CT) has been dated to 70,00075,000 years ago in Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans, Nature 505, 87–91 (02 January 2014)
  2. 1 2 Kamin M, Saag L, Vincente M, et al. (April 2015). "A recent bottleneck of Y chromosome diversity coincides with a global change in culture". Genome Research. 25 (4): 459–466. doi:10.1101/gr.186684.114. PMC   4381518 . PMID   25770088.
  3. Haber M, Jones AL, Connel BA, Asan, Arciero E, Huanming Y, Thomas MG, Xue Y, Tyler-Smith C (June 2019). "A Rare Deep-Rooting D0 African Y-chromosomal Haplogroup and its Implications for the Expansion of Modern Humans Out of Africa". Genetics. 212 (4): 1421–1428. doi:10.1534/genetics.119.302368. PMC   6707464 . PMID   31196864.
  4. 1 2 Underhill and Kivisild; Kivisild, T (2007). "Use of Y Chromosome and Mitochondrial DNA Population Structure in Tracing Human Migrations". Annu. Rev. Genet. 41 (1): 539–64. doi:10.1146/annurev.genet.41.110306.130407. PMID   18076332. S2CID   24904955.
  5. 1 2 Stone, Linda; Paul F. Lurquin; Luigi Luca Cavalli-Sforza (2007). "Voyages, Prehistoric Human Expansions". Genes, Culture, and Human Evolution. p. 187. ISBN   978-1-4051-5089-7.
  6. 1 2 3 Karafet; et al. (2008). "New Binary Polymorphisms Reshape and Increase Resolution of the Human Y-Chromosomal Haplogroup Tree". Genome Research. 18 (5): 830–8. doi:10.1101/gr.7172008. PMC   2336805 . PMID   18385274.
  7. 1 2 Darwinian Detectives: Revealing the Natural History of Genes and Genomes, by Norman A. Johnson, 2007, ISBN   0-19-530675-9, ISBN   978-0-19-530675-0
  8. Genes, Culture, and Human Evolution: A Synthesis, By Linda Stone, Paul F. Lurquin, 2007, ISBN   1-4051-5089-0, page 187
  9. Pereira et al. (2010), Linking the sub-Saharan and West Eurasian gene pools: maternal and paternal heritage of the Tuareg nomads from the African Sahel, European Journal of Human Genetics (2010) 18, 915–923; doi : 10.1038/ejhg.2010.21