U.S. Route 34 (US 34) is an east–west United States highway that runs for 1,122 miles (1,806 km) from north-central Colorado to the western suburbs of Chicago. Through Rocky Mountain National Park it is known as the Trail Ridge Road where it reaches elevation 12,183 feet (3,713 m), making it the third highest paved through highway in the United States. The highway's western terminus is Granby, Colorado at US 40. Its eastern terminus is in Berwyn, Illinois at Illinois Route 43 and Historic US 66.
Illinois Route 50 (IL 50) is a 66.49-mile-long (107.01 km) north–south state highway in northeastern Illinois. It runs from the junction with U.S. Route 45 (US 45) and U.S. Route 52 (US 52) in West Kankakee north to US 41 in Skokie. In Chicago and the suburbs it's known as Cicero Avenue. Before this, Cicero Avenue was previously known as 48th Avenue, owing to its City of Chicago address of 4800 West.
Illinois Route 171 (IL 171) is a 38.61-mile-long (62.14 km) north–south state highway in northeastern Illinois. It runs from U.S. Route 6 (US 6) in Joliet north to Illinois Route 72 at the Chicago–Park Ridge border. The section of IL 171 on Archer Avenue from Joliet to Summit is historically significant, originating as a Native American trail, and later serving for a time as part of the first numbered highway between St. Louis and Chicago.
Illinois Route 56 is a 32.52-mile-long (52.34 km) east–west state highway in northern and northeastern Illinois. It runs from the interchange of Illinois Route 47 at U.S. Route 30 in Sugar Grove east to US 12/US 20/US 45 by Bellwood.
Illinois Route 59 is a north–south state highway in northeastern Illinois. It runs south from Illinois Route 173 in Antioch to I-55 in Shorewood, spanning the north–south width of Chicago's western suburbs. This is a distance of 71.13 miles (114.47 km).
Lake Street is an east–west street in Chicago and part of its suburbs. A portion of Lake Street is designated as U.S. Route 20. Lake Street begins in downtown Chicago and travels west to the eastern terminus of the Elgin Bypass around suburban Elgin. The street travels west through the city and then begins to travel in a northwest fashion through several suburbs. The street is a distance of roughly 34.4 miles (55.4 km).
U.S. Route 6 (US 6) in the state of Illinois is an east–west arterial surface road that runs 179.88 miles (289.49 km) from the city of Moline in the Quad Cities area to Lansing at the Indiana state line.
U.S. Route 30 (US 30) is an east–west arterial surface road in northern Illinois. It runs from across the Mississippi River from Clinton, Iowa, to Lynwood at the Indiana state line. This is a distance of 153.79 miles (247.50 km).
U.S. Route 12 (US 12) in the U.S. state of Illinois is an arterial highway that runs northwest to southeast through the Chicago metropolitan area. It enters Illinois at the Wisconsin border north of Richmond, and exits into Hammond, Indiana, from Chicago near the foot of the onramp to the Indiana Toll Road ; as it exits Illinois, the route is also concurrent with US 20 and US 41. Within Illinois, US 12 runs for a distance of 85.14 miles (137.02 km).
U.S. Route 34 (US 34) is an east–west highway In the state of Illinois that runs from the Iowa state line at Gulfport, west of Galesburg, to Illinois Route 43 (IL 43) and Historic U.S. Route 66 at Harlem Avenue in Berwyn. The entire highway in Illinois is named the Walter Payton Memorial Highway after Pro Football Hall of Famer Walter Payton, who wore #34 for the Chicago Bears. The highway is 211.37 miles (340.17 km) long within the state.
North Avenue is a major east–west street in Chicago, Illinois, and its western suburbs. Starting at St. Charles's eastern border with West Chicago, its name changes from Main Street to North Avenue, just east of the Kane/DuPage county line. From there, it travels straight east, carrying Illinois Route 64 until LaSalle Drive in Chicago. Illinois Route 64 then continues north onto LaSalle Drive for a very short distance until ending at U.S. Route 41, while North Avenue continues east for less than one-half mile, changing its name to North Boulevard at Clark Street, and then continuing until its termination in a cul-de-sac at 200 East, just west of Lake Shore Drive. From Illinois Route 43 to its east end, North Avenue is within the city limits of Chicago.
U.S. Route 41 (US 41) in the U.S. state of Illinois runs north from the Indiana border beneath the Chicago Skyway on Indianapolis Boulevard to the Wisconsin border north of the northern terminus of the Tri-State Tollway with Interstate 94. It is the only north–south U.S. Route to travel through a significant portion of the city of Chicago, carrying Lake Shore Drive through the central portion of the city along the lakefront. US 41 in Illinois is 64.81 miles (104.30 km) in length.
U.S. Route 54 (US 54) in Illinois is a 23.9-mile-long (38.5 km) east–west highway that travels from the Champ Clark Bridge on the Missouri state line to I-72/US 36/IL 107 south of Griggsville. At its greatest extent, US 54 used to continue east to Springfield, then northeast to Onarga, and then north all the way to Downtown Chicago.
U.S. Route 45 in the state of Illinois is a major north–south U.S. Highway that runs from the Brookport Bridge over the Ohio River at Brookport north through rural sections of eastern Illinois and then through the suburbs of Chicago to the Wisconsin state line east of Antioch. This is a distance of 428.99 miles (690.39 km). US 45 is the longest numbered route in Illinois.
Several special routes of U.S. Route 30 exist. In order from west to east they are as follows.
Orchard Road is a major north-south road carrying traffic through Kane and Kendall Counties in northeast Illinois. It exists as a county highway in both counties. It runs from Oswego through Aurora to North Aurora, where it connects with Randall Road. Much traffic continues northward on Randall Road to access Batavia, Illinois and points northward in the Fox Valley.
Pershing Road is an east-west street on the south side of Chicago and in its immediate western suburbs in Cook County, Illinois. It is precisely four miles south of Madison Street, the division point between north and south street numbering, and marks the 3900 South point in the region's street numbering system. Its western segment, more commonly referred to as 39th Street, runs east from a U.S. Route 34 in Lyons to Illinois Route 50 in Cicero. Its eastern segment, officially known as Pershing Road, runs east from a cul-de-sac at 3600 West to Oakwood Boulevard, which continues east ending at U.S. Route 41. All of the eastern segment lies within the city of Chicago.
Garfield Boulevard is an east-west street on the south side of Chicago and its immediate western suburbs. Its western segment, entirely known as 55th Street, runs east from Maple Avenue in Downers Grove until it becomes Joliet Road in Countryside. Its eastern segment, known only as Garfield Boulevard from Western Avenue in Gage Park to Elsworth Drive in Washington Park, runs east from Archer Avenue and Narragansett Avenue to South Shore Drive, just west of U.S. Route 41. All of the eastern segment of 55th Street lies within the city limits of Chicago.
Dempster Street is a major east–west street in the northern suburbs of Chicago. It is assigned 8800 North in the Chicago address system, being located 11 miles (18 km) north of Madison Street.
1st Avenue, also known as Cumberland Avenue and Thatcher Avenue for parts of its northern segment, is a north-south street in Chicago and its western suburbs. It marks 8400 West in the Chicago address system, being located ten and one-half miles west of State Street.
US 34 / Historic US 66 
US 30 in Montgomery 
