| Tournament details | |
|---|---|
| Dates | April - 7 December 1980 |
| Teams | 28 (from 1 confederation) |
| Final positions | |
| Champions | |
| Runners-up | |
| Tournament statistics | |
| Matches played | 48 |
| Goals scored | 134 (2.79 per match) |
← 1979 1981 → | |
The 1980 season of the African Cup Winners' Cup football club tournament was won by Tout Puissant Mazembe in two-legged final victory against Africa Sports. This was the sixth season that the tournament took place for the winners of each African country's domestic cup. Twenty-eight sides entered the competition, with Dingareh and Ader Club withdrawing before the 1st leg of the first round. No preliminary round took place during this season of the competition.
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Africa Sports National | w/o | | — | — |
| Atlético Malabo | 3-5 | | 2-2 | 1-3 |
| Buffles du Borgou FC | 4-7 | | 1-2 | 3-5 |
| Casa Sport | 6-1 | | 5-1 | 1-0 |
| Eleven Wise | 4-0 | | 3-0 | 1-0 |
| Espérance | w/o | | — | — |
| RC Kadiogo | 5-5 (4-2 p) | | 4-1 | 1-4 |
| KCC | 5-2 | | 3-1 | 2-1 |
| NA Hussein-Dey | 7-1 | | 7-0 | 0-1 |
| Matlama FC | 5-2 | | 2-0 | 3-2 |
| Pan African FC | 5-4 | | 4-3 | 1-1 |
| Township Rollers | 3-6 | | 2-2 | 1-4 |
| Dynamo Douala | bye | |||
| Horoya AC | bye | |||
| Ramogi United | bye | |||
| Shooting Stars F.C. | bye |
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Africa Sports National | abd1 | | 3-2 | 1-1 |
| OC Agaza | 0-0 (2-1 p) | | 0-0 | 0-0 |
| Casa Sport | 1-3 | | 1-1 | 0-2 |
| Eleven Wise | 3-2 | | 2-1 | 1-1 |
| RC Kadiogo | w/o | | — | — |
| Matlama FC | 1-1 (a) | | 1-1 | 0-0 |
| Pan African FC | 1-2 | | 0-1 | 1-2 |
| TP Mazembe | 3-2 | | 1-0 | 2-2 |
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| OC Agaza | 1-2 | | 1-1 | 0-1 |
| Eleven Wise | 2-5 | | 1-1 | 1-4 |
| Ramogi United | 0-4 | | 0-3 | 0-1 |
| TP Mazembe | 3-3 (3-0 p) | | 2-1 | 1-2 |
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Africa Sports National | 3-2 | | 1-0 | 2-2 |
| TP Mazembe | 3-2 | | 1-0 | 2-2 |
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Africa Sports National | 1-4 | | 1-3 | 0-1 |
| African Cup Winners' Cup Winners |
|---|
| Tout Puissant Mazembe First title |