| Tournament details | |
|---|---|
| Dates | 31 January 2001 – 1 December 2001 |
| Teams | 33 |
| Final positions | |
| Champions |  JS Kabylie (1st title) |
| Runners-up |  Ismaily |
| Tournament statistics | |
| Matches played | 57 |
The 2000 CAF Cup was the 9th edition of the CAF Cup, the African continental club competition for runners up of the respective domestic leagues. It was won by Algerian team JS Kabylie who beat Ismaily SC of Egypt on the away goals rule in the final, after they finished level on aggregate 1-1.
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
Chingale de Tete  | 1-1 (4-2) |  Sony Ela Nguema | 0-1 | 1-0 |
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Ismaily | 7-4 |  Almahalla Tripoli | 5-1 | 2-3 |
Hay Al-Arab SC  | 2-0 |  Shabana Kisii | 2-0 | 0-0 |
Mtibwa Sugar FC  | 5-1 |  Mochudi Centre Chiefs | 3-0 | 2-1 |
Cotonsport Garoua  | 4-1 |  Tout Puissant Mystère | 2-0 | 2-1 |
Awassa City F.C.  | 2-1 |  Mukura Victory | 2-0 | 0-1 |
Iwuanyanwu Nationale  | 5-2 |  Mbilinga FC | 3-0 | 2-2 |
Étoile du Sahel  | 11-0 | Chingale de Tete | 10-0 | 1-0 |
Compagnie Sucrière  | 2-0 |  Real Banjul | 1-0 | 1-0 |
Stade d'Abidjan  | w/o1 |  AC Semassi F.C. | — | — |
| CA Bizertin | 3-2 |  USFA | 2-0 | 1-2 |
| JS Kabylie | w/o1 |  Aslad Moundou | — | — |
TP Mazembe  | 7-2 |  Académica do Lobito | 4-0 | 3-2 |
Wydad AC  | w/o1 |  Saint Anthony | — | — |
USFAS  | 2-3 |  Cape Coast Dwarfs | 2-0 | 0-3 |
Kaizer Chiefs  | 6-2 |  Mbabane Highlanders | 5-2 | 1-0 |
Nchanga Rangers F.C.  | 2-0 |  DSA Antananarivo | 1-0 | 1-0 |
1 AC Semassi, Aslad Moundou and Saint Anthony's withdrew before first leg
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Ismaily | w/o1 | Hay Al-Arab SC | 8-0 | —1 |
| Mtibwa Sugar FC | 0-3 | Cotonsport Garoua | 0-1 | 0-2 |
| Awassa City F.C. | 2-3 | Iwuanyanwu Nationale | 1-1 | 1-2 |
| Étoile du Sahel | 4-2 | Compagnie Sucrière | 3-0 | 1-2 |
| Stade d'Abidjan | (a) 4-4 | CA Bizertin | 3-0 | 1-4 |
| JS Kabylie | 5-2 | TP Mazembe | 5-0 | 0-2 |
| Wydad AC | 2-3 | Cape Coast Dwarfs | 2-1 | 0-2 |
| Kaizer Chiefs | 0-2 | Nchanga Rangers F.C. | 0-2 | 0-0 |
1 Hay El Arab withdrew after 1st leg
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Stade d'Abidjan | 2-1 | Cotonsport Garoua | 2-0 | 0-1 |
| Ismaily | 6-0 | Cape Coast Dwarfs | 4-0 | 2-0 |
| JS Kabylie | 1-1 (4-1 p) | Étoile du Sahel | 1-0 | 0-1 |
| Nchanga Rangers F.C. | 1-2 | Iwuanyanwu Nationale | 1-0 | 0-2 |
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Ismaily | 7-0 | Stade d'Abidjan | 5-0 | 2-0 |
| Iwuanyanwu Nationale | 1-2 | JS Kabylie | 1-1 | 0-1 |
| Ismaily | 5 – 0 | Stade d'Abidjan |
|---|---|---|
Keita  25'Ibrahim 38'Abdel Baky 77'Utaka 83'Barakat 86' (pen.) |
| Stade d'Abidjan | 0 – 2 | Ismaily |
|---|---|---|
| Keita Utaka 83' |
Ismaily won 7-0 on aggregate and advanced to the final.
| Iwuanyanwu Nationale | 1 – 1 | JS Kabylie |
|---|---|---|
| 78' (pen.) | Moussouni 21' |
| JS Kabylie | 1 – 0 | Iwuanyanwu Nationale |
|---|---|---|
| Moussouni 20' |
JS Kabylie won 2-1 on aggregate and advanced to the final.
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Ismaily | 1-1 (a) | JS Kabylie | 1-1 | 0-0 |
| Ismaily | 1 – 1 | JS Kabylie |
|---|---|---|
| Barakat 60' (pen.) | Report | Bendahmane 72' |
| JS Kabylie | 0 – 0 | Ismaily |
|---|---|---|
1-1 on aggregate, JS Kabylie won on away goals rule
| 2000 CAF Cup Winners |
|---|
 |
| JS Kabylie First Title |
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