| Singles | |
|---|---|
| 2006 Queen's Club Championships | |
| Champion |  Lleyton Hewitt |
| Runner-up |  James Blake |
| Final score | 6–4, 6–4 |
| Draw | 56 |
| Seeds | 16 |
Andy Roddick was the defending champion but lost in the semifinals to James Blake.
Lleyton Hewitt won in the final 6–4, 6–4 against Blake.
The top eight seeds receive a bye into the second round.
Rafael Nadal (quarterfinals)
Ivan Ljubičić (third round) Andy Roddick (semifinals)
Nikolay Davydenko (second round) James Blake (final)
Fernando González (quarterfinals)
Radek Štěpánek (second round) Lleyton Hewitt (champion) Robby Ginepri (third round)
Thomas Johansson (first round)
Sébastien Grosjean (second round) Andre Agassi (first round) Gaël Monfils (quarterfinals) Paul-Henri Mathieu (first round) Dmitry Tursunov (quarterfinals)
Paradorn Schrichapan (third round)| Quarterfinals | Semifinals | Final | ||||||||||||||||||
| 1 | Rafael Nadal | 6 | 3 | 0r | ||||||||||||||||
| 8 | Lleyton Hewitt | 3 | 6 | 0 | ||||||||||||||||
| 8 | Lleyton Hewitt | 6 | 3 | 6 | ||||||||||||||||
 Tim Henman | 3 | 6 | 2 | |||||||||||||||||
| 15 | Dmitry Tursunov | 3 | 61 | |||||||||||||||||
| Tim Henman | 6 | 77 | ||||||||||||||||||
| 8 | Lleyton Hewitt | 6 | 6 | |||||||||||||||||
| 5 | James Blake | 4 | 4 | |||||||||||||||||
| 6 | Fernando González | 4 | 3 | |||||||||||||||||
| 3 | Andy Roddick | 6 | 6 | |||||||||||||||||
| 3 | Andy Roddick | 5 | 4 | |||||||||||||||||
| 5 | James Blake | 7 | 6 | |||||||||||||||||
| 5 | James Blake | 6 | 0 | |||||||||||||||||
| 13 | Gaël Monfils | 1 | 0r | |||||||||||||||||
| First round | Second round | Third round | Quarterfinals | ||||||||||||||||||||||||
| 1 | R Nadal | 77 | 6 | ||||||||||||||||||||||||
| WC | J Baker | 1 | 3 | WC | M Fish | 61 | 1 | ||||||||||||||||||||
| WC | M Fish | 6 | 6 | 1 | R Nadal | 2 | 77 | 77 | |||||||||||||||||||
 S Greul | 3 | 3 | Q | F Verdasco | 6 | 63 | 63 | ||||||||||||||||||||
| Q | F Verdasco | 6 | 6 | Q | F Verdasco | 6 | 5 | 6 | |||||||||||||||||||
 H-T Lee | 77 | 63 | 6 | H-T Lee | 2 | 7 | 4 | ||||||||||||||||||||
| 14 | P-H Mathieu | 64 | 77 | 4 | 1 | R Nadal | 6 | 3 | 0r | ||||||||||||||||||
| 10 | T Johansson | 66 | 6 | 64 | 8 | L Hewitt | 3 | 6 | 0 | ||||||||||||||||||
 M Mirnyi | 78 | 3 | 77 | M Mirnyi | 6 | 6 | |||||||||||||||||||||
| WC | F López | 1 | 64 |  D Bracciali | 1 | 3 | |||||||||||||||||||||
| D Bracciali | 6 | 77 | M Mirnyi | 6 | 1 | 64 | |||||||||||||||||||||
| Q | M Lee | 3 | 2 | 8 | L Hewitt | 4 | 6 | 77 | |||||||||||||||||||
| F Vicente | 6 | 6 | F Vicente | 6 | 4 | 2 | |||||||||||||||||||||
| 8 | L Hewitt | 4 | 6 | 6 | |||||||||||||||||||||||
| First round | Second round | Third round | Quarterfinals | ||||||||||||||||||||||||
| 4 | N Davydenko | 6 | 3 | 1 | |||||||||||||||||||||||
 Y-T Wang | 6 | 6 | Y-T Wang | 2 | 6 | 6 | |||||||||||||||||||||
| J Björkman | 3 | 3 | Y-T Wang | 3 | 6 | 1 | |||||||||||||||||||||
| D Udomchoke | 3 | 7 | 6 | 15 | D Tursunov | 6 | 3 | 6 | |||||||||||||||||||
| T Zíb | 6 | 5 | 0 | D Udomchoke | 3 | 6 | 2 | ||||||||||||||||||||
| WC | A Bogdanović | 64 | 4 | 15 | D Tursunov | 6 | 2 | 6 | |||||||||||||||||||
| 15 | D Tursunov | 77 | 6 | 15 | D Tursunov | 3 | 61 | ||||||||||||||||||||
| 12 | A Agassi | 4 | 4 | T Henman | 6 | 77 | |||||||||||||||||||||
| T Henman | 6 | 6 | T Henman | 6 | 6 | ||||||||||||||||||||||
 R Delgado | 6 | 77 | R Delgado | 2 | 4 | ||||||||||||||||||||||
| L Dlouhý | 4 | 63 | T Henman | 6 | 6 | ||||||||||||||||||||||
| J Benneteau | 4 | 1 | N Mahut | 3 | 4 | ||||||||||||||||||||||
| N Mahut | 6 | 6 | N Mahut | 6 | 4 | 6 | |||||||||||||||||||||
| 7 | R Štěpánek | 4 | 6 | 2 | |||||||||||||||||||||||
| First round | Second round | Third round | Quarterfinals | ||||||||||||||||||||||||
| 6 | F González | 77 | 77 | ||||||||||||||||||||||||
| G Rusedski | 7 | 3 | 2r | Q | A Dupuis | 65 | 62 | ||||||||||||||||||||
| Q | A Dupuis | 5 | 6 | 3 | 6 | F González | 6 | 3 | 6 | ||||||||||||||||||
 W Moodie | 3 | 4 | WC | M Philippoussis | 2 | 6 | 3 | ||||||||||||||||||||
| WC | M Philippoussis | 6 | 6 | WC | M Philippoussis | 77 | 4 | 6 | |||||||||||||||||||
| I Minář | 3 | 64 | 11 | S Grosjean | 65 | 6 | 3 | ||||||||||||||||||||
| 11 | S Grosjean | 6 | 77 | 6 | F González | 4 | 3 | ||||||||||||||||||||
| 16 | P Srichaphan | 6 | 77 | 3 | A Roddick | 6 | 6 | ||||||||||||||||||||
 D Norman | 4 | 65 | 16 | P Srichaphan | 6 | 5 | 6 | ||||||||||||||||||||
| Y-H Lu | 6 | 79 | Y-H Lu | 3 | 7 | 4 | |||||||||||||||||||||
 G Müller | 4 | 67 | 16 | P Srichaphan | 65 | 3 | |||||||||||||||||||||
| Q |  F Dancevic | 4 | 6 | 6 | 3 | A Roddick | 77 | 6 | |||||||||||||||||||
 K Carlsen | 6 | 3 | 3 | Q | F Dancevic | 6 | 4 | 3 | |||||||||||||||||||
| 3 | A Roddick | 2 | 6 | 6 | |||||||||||||||||||||||
| First round | Second round | Third round | Quarterfinals | ||||||||||||||||||||||||
| 5 | J Blake | 7 | 6 | ||||||||||||||||||||||||
| J Gimelstob | 79 | 6 | J Gimelstob | 5 | 1 | ||||||||||||||||||||||
 R Sluiter | 67 | 2 | 5 | J Blake | 6 | 3 | 6 | ||||||||||||||||||||
| A Murray | 63 | 6 | 2 | 9 | R Ginepri | 3 | 6 | 3 | |||||||||||||||||||
 J Tipsarević | 77 | 3 | 6 | J Tipsarević | 64 | 4 | |||||||||||||||||||||
| P Goldstein | 6 | 5 | 1 | 9 | R Ginepri | 77 | 6 | ||||||||||||||||||||
| 9 | R Ginepri | 3 | 7 | 6 | 5 | J Blake | 6 | 0 | |||||||||||||||||||
| 13 | G Monfils | 77 | 77 | 13 | G Monfils | 1 | 0r | ||||||||||||||||||||
 J Melzer | 62 | 62 | 13 | G Monfils | 6 | 6 | |||||||||||||||||||||
| I Kunitsyn | 4 | 4 | B Reynolds | 1 | 2 | ||||||||||||||||||||||
| B Reynolds | 6 | 6 | 13 | G Monfils | 713 | 7 | |||||||||||||||||||||
 R Sabău | 6 | 6 | 2 | I Ljubičić | 611 | 5 | |||||||||||||||||||||
| R Vik | 3 | 3 | R Sabău | 66 | 2 | ||||||||||||||||||||||
| 2 | I Ljubičić | 78 | 6 | ||||||||||||||||||||||||
Defending champion Roger Federer defeated Andre Agassi in the final, 6–3, 2–6, 7–6(7–1), 6–1 to win the men's singles tennis title at the 2005 US Open. It was his second US Open title and sixth major title overall. This was Agassi's last appearance in a major final.
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Andy Roddick was the defending champion, but lost in the semifinals to eventual champion Andy Murray.
Lleyton Hewitt was the defending champion and won in the final 7–6(7–3), 7–6(7–3) against Tim Henman.
Lleyton Hewitt was the defending champion but lost in the quarterfinals to Sébastien Grosjean.
Andy Roddick was the defending champion and won in the final 7–6(7–4), 6–4 against Sébastien Grosjean.
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