Lisa Raymond and Samantha Stosur defeated Elena Dementieva and Flavia Pennetta in the final, 6–2, 5–7, 6–3 to win the women's doubles tennis title at the 2005 US Open.
Virginia Ruano Pascual and Paola Suárez were the two-time defending champions, but they were defeated in the second round by Anna Chakvetadze and Elena Vesnina.
Cara Black and Liezel Huber were the defending champions, but did not play together. Black partnered with Rennae Stubbs and Huber partnered with Martina Navratilova but both pairs lost to Yan Zi and Zheng Jie, in the semifinals and quarterfinals respectively.
Nathalie Dechy and Vera Zvonareva defeated Dinara Safina and Katarina Srebotnik in the final, 7–6(7–5), 7-5 to win the women's doubles title at the 2006 US Open.
Lisa Raymond and Samantha Stosur were the defending champions, but lost in the semifinals to Katarina Srebotnik and Ai Sugiyama.
Virginia Ruano Pascual and Paola Suárez were the defending champions, and successfully defended their title, defeating Cara Black and Liezel Huber in the final 4–6, 6–3, 6–3 Cara Black would fail to complete the career grand slam in women's doubles because of this loss
Cara Black and Rennae Stubbs were the defending champions, but did not play together. Stubbs partnered with Lisa Raymond but lost in the first round to Stéphanie Cohen-Aloro and Selima Sfar.
Twelfth-seeded Yan Zi and Zheng Jie defeated first-seeded Lisa Raymond and Samantha Stosur, 2–6, 7–6 (7), 6–3 to win the women's doubles title at the 2006 Australian Open.
Nadia Petrova and Martina Navratilova were the defending champions, but Navratilova retired from the sport on September 10, 2006, and only Petrova competed that year.
Petrova partnered with Svetlana Kuznetsova, but lost in the quarterfinals to Nathalie Dechy and Sun Tiantian.
Alicia Molik and Mara Santangelo were the defending champions, but lost in the first round to Sara Errani and Bethanie Mattek.
Cara Black and Liezel Huber were the defending champions, but lost in the quarterfinals to sisters Alona Bondarenko and Kateryna Bondarenko.
Martina Hingis and Maria Kirilenko were the defending champions, but Hingis retired on November 1, 2007, and Kirilenko teamed up with Ágnes Szávay.
Shinobu Asagoe and Ai Sugiyama were the defending champions. They were both present but did not compete together.
Asagoe partnered with Tathiana Garbin, but lost in the semifinals to Conchita Martínez and Virginia Ruano Pascual.
Sugiyama partnered with Daniela Hantuchová, but lost in the semifinals to Anna-Lena Grönefeld and Martina Navratilova.
Lucie Hradecká and Renata Voráčová were the defending champions, but Voráčová chose not to participate, and only Hradecká competed that year. Hradecká partnered up with Andreja Klepač, but they lost in the quarterfinals to Vera Dushevina and Ekaterina Makarova.
Katarina Srebotnik and Ai Sugiyama were the defending champions, but Srebotnik chose not to participate this year due to injury.
Anabel Medina Garrigues and Caroline Wozniacki were the defending champion, but Wozniacki chose not to participate this year. Medina Garrigues partnered with Virginia Ruano Pascual, but they lost in the second round against Anastasia Pavlyuchenkova and Yanina Wickmayer.
Hsieh Su-Wei and Peng Shuai won in the final 6–3, 6–1 against Alla Kudryavtseva and Ekaterina Makarova.
María José Martínez and Anabel Medina Garrigues won in the final 6–4, 6–7(5–7), 7–5 against Virginia Ruano Pascual and Paola Suárez.
Eva Birnerová and Jarmila Gajdošová are the defending champions but only Eva Birnerová participated this year.
Émilie Loit and Nicole Pratt were the defending champions, but both chose not to participate that year.
María José Martínez Sánchez and Anabel Medina Garrigues were the defending champions, but none competed this year. Martínez Sánchez decided to compete in Scottsdale at the same week.
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Mara Santangelo 
Katarina Srebotnik 
Anabel Medina Garrigues 
