Bob and Mike Bryan were the defending champions, but lost in the third round to Leoš Friedl and Mikhail Youzhny.
Xavier Malisse and Olivier Rochus were the defending champions, but lost in the third round against third seeds and eventual finalists Bob & Mike Bryan.
Jonas Björkman and Todd Woodbridge were the two-time defending champions but did not play together. Björkman partnered with Max Mirnyi and Woodbridge partnered with Mahesh Bhupathi but both pairs lost to Stephen Huss and Wesley Moodie, in the semifinals and the second round respectively.
Michaël Llodra and Fabrice Santoro were the defending champions, but they lost in quarterfinals 6–7(2), 5–7, against Jonas Björkman and Max Mirnyi.
The 2007 US Open men's doubles tennis tournament was held from 27 August to 9 September 2007, at USTA Billie Jean King National Tennis Center at Flushing Meadows, New York City.
Bob Bryan and Mike Bryan were the defending champions, but lost in the quarterfinals to Mahesh Bhupathi and Mark Knowles.
Hugo Armando and Xavier Malisse were the defending champions, but lost in the first round to Bob Bryan and Mike Bryan.
Eric Butorac and Jamie Murray were the defending champions. They were both present but did not compete together.
Butorac partnered with Todd Perry, but lost in the first round to Scott Lipsky and David Martin.
Murray partnered with Max Mirnyi, but lost in the first round to Thomas Johansson and Robert Lindstedt.
Jonathan Erlich and Andy Ram were the defending champions, but Erlich chose not to participate due to an elbow injury, and only Ram competed that year.
Ram partnered with Max Mirnyi, but lost to Feliciano López and Fernando Verdasco in the second round.
Max Mirnyi and Jamie Murray were the defending champions, but did not compete together that year.
Mirnyi partnered with Ashley Fisher, but lost in the first round to Bob Bryan and Mike Bryan.
Murray partnered with Dušan Vemić, but lost in the quarterfinals to Rajeev Ram and Bobby Reynolds.
Bob Bryan and Mike Bryan won in the final, 6–4, 6–4, over Marcelo Melo and André Sá.
Liezel Huber and Bob Bryan were the defending champions, but Bryan chose to not compete this year in mixed doubles.
Mahesh Bhupathi and Leander Paes were the defending champions but they competed with different partners that year, Bhupathi with Max Mirnyi and Paes with Michael Hill.
Daniel Nestor and Nenad Zimonjić were the defending champions, but decided not to participate together. Nestor partnered Max Mirnyi, while Zimonjić teamed up with Michaël Llodra. Mirnyi and Nestor defeated Zimonjić and Llodra in the semifinals, 7–6(7–4), 7–6(7–5). In the final, they won against Juan Sebastián Cabal and Eduardo Schwank 7–6(7–3), 3–6, 6–4 for their first Grand Slam doubles title as a team.
Bob and Mike Bryan were the defending champions and they reached the final. Michaël Llodra and Nenad Zimonjić defeated them 6–4, 6–7(5–7), [10–5] and won the title.
Bob and Mike Bryan were the three-time defending champions, but lost to the unseeded pair Leander Paes and Radek Štěpánek, 7–6(7–1), 6–2, in the final. With this win Paes completed the career grand slam in Men's doubles.
Bob Bryan and Mike Bryan were the defending champions but lost in the final to top seeds Max Mirnyi and Daniel Nestor, 6–3, 6–4.
Bob and Mike Bryan were the defending champions, but lost in the semifinals to Jonathan Marray and Frederik Nielsen.
Mark Knowles and Daniel Nestor were the defending champions, but lost in the first round to Paul Goldstein and Jim Thomas.
James Blake and Sam Querrey were the defending champions, but lost in the first round to Philipp Marx and Florin Mergea.
Jamie Murray and John Peers won the title, defeating Bob Bryan and Mike Bryan in the final, 1–6, 7–6(7–3), [12–10].
Bob and Mike Bryan were the defending champions, but lost in the final to Eric Butorac and Raven Klaasen, 4–6, 4–6.
Scott Lipsky 
