The last four stages of the 2010 Copa Santander Libertadores are the knockout stages: the Round of 16, the Quarterfinals, the Semifinals, and the Finals.
The remaining stages of the tournament constitute a single-elimination tournament. In each stage, the teams will play an opponent in a two-legged tie on a home-away basis. Each team will earn three points for a win, one point for a draw, and zero points for a loss. The team with the most points at the end of each tie will advance. Fourteen teams will advance from the second stage; the eight group winners, the six group runners-up teams with the best records. The remaining two entries will go to Mexican clubs Guadalajara and San Luis.
The following criteria will be used for breaking ties on points:
The 16 qualified teams were seeded according to their results in the Second Stage. The top teams from each group were seeded 1–8, with the team with the most points as seed 1 and the team with the least as seed 8. The second-best teams from each group were seeded 9–16, with the team with the most points as seed 9 and the team with the least as seed 16. Guadalajara and San Luis were given the 13 and 14 seed, respectively, which they had earned in the 2009 Copa Libertadores.
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Round of 16 | Quarterfinals | Semifinals | Finals | ||||||||||||||||||||
2 | São Paulo (p) | 0 | 0 (3) | ||||||||||||||||||||
15 | Universitario | 0 | 0 (1) | ||||||||||||||||||||
2 | São Paulo | 2 | 2 | ||||||||||||||||||||
10 | Cruzeiro | 0 | 0 | ||||||||||||||||||||
7 | Nacional | 1 | 0 | ||||||||||||||||||||
10 | Cruzeiro | 3 | 3 | ||||||||||||||||||||
2 | São Paulo | 0 | 2 | ||||||||||||||||||||
6 | Internacional (a) | 1 | 1 | ||||||||||||||||||||
3 | Estudiantes | 1 | 3 | ||||||||||||||||||||
14 | San Luis | 0 | 1 | ||||||||||||||||||||
3 | Estudiantes | 0 | 2 | ||||||||||||||||||||
6 | Internacional (a) | 1 | 1 | ||||||||||||||||||||
6 | Internacional (a) | 1 | 2 | ||||||||||||||||||||
11 | Banfield | 3 | 0 | ||||||||||||||||||||
6 | Internacional | 2 | 3 | ||||||||||||||||||||
13 | Guadalajara | 1 | 2 | ||||||||||||||||||||
8 | U. de Chile | 1 | 2 | ||||||||||||||||||||
9 | Alianza Lima | 0 | 2 | ||||||||||||||||||||
8 | U. de Chile (a) | 3 | 1 | ||||||||||||||||||||
16 | Flamengo | 2 | 2 | ||||||||||||||||||||
1 | Corinthians | 0 | 2 | ||||||||||||||||||||
16 | Flamengo (a) | 1 | 2 | ||||||||||||||||||||
8 | U. de Chile | 1 | 0 | ||||||||||||||||||||
13 | Guadalajara | 1 | 2 | ||||||||||||||||||||
5 | Libertad | 0 | 2 | ||||||||||||||||||||
12 | Once Caldas | 0 | 1 | ||||||||||||||||||||
5 | Libertad | 0 | 2 | ||||||||||||||||||||
13 | Guadalajara | 3 | 0 | ||||||||||||||||||||
4 | Vélez Sársfield | 0 | 2 | ||||||||||||||||||||
13 | Guadalajara | 3 | 0 |
Teams | Scores | Tie-breakers | |||||
---|---|---|---|---|---|---|---|
Team #1 | Points | Team #2 | 1st leg | 2nd leg | GD | AG | Pen. |
Corinthians | 3:3 | Flamengo | 0–1 | 2–1 | 0:0 | 0:1 | — |
São Paulo | 2:2 | Universitario | 0–0 | 0–0 | 0:0 | 0:0 | 3–1 |
Estudiantes | 6:0 | San Luis | 1–0 | 3–1 | — | — | — |
Vélez Sársfield | 3:3 | Guadalajara | 0–3 | 2–0 | −1:+1 | — | — |
Libertad | 4:1 | Once Caldas | 0–0 | 2–1 | — | — | — |
Internacional | 3:3 | Banfield | 1–3 | 2–0 | 0:0 | 1:0 | — |
Nacional | 0:6 | Cruzeiro | 1–3 | 0–3 | — | — | — |
Universidad de Chile | 4:1 | Alianza Lima | 1–0 | 2–2 | — | — | — |
Flamengo | 1–0 | Corinthians |
---|---|---|
Adriano 66' (pen.) | Report |
Corinthians | 2–1 | Flamengo |
---|---|---|
David 28' (o.g.) Ronaldo 39' | Report | Vágner Love 49' |
Corinthians 3–3 Flamengo on points. Flamengo advanced on away goals.
São Paulo | 0–0 | Universitario |
---|---|---|
Report | ||
Penalties | ||
Ceni Hernanes Marcelinho Dagoberto | 3–1 | Ramírez Alva Galván Labarthe |
São Paulo 2–2 Universitario on points. São Paulo advanced on penalties.
San Luis | 0–1 | Estudiantes |
---|---|---|
Report | González 25' |
Estudiantes | 3–1 | San Luis |
---|---|---|
González 4' Benítez 50', 55' | Report | de la Torre 7' |
Estudiantes advanced on points 6–0.
Guadalajara | 3–0 | Vélez Sársfield |
---|---|---|
Bravo 25', 79' Reynoso 90+2' (pen.) | Report |
Vélez Sársfield | 2–0 | Guadalajara |
---|---|---|
Silva 3' Zárate 88' | Report |
Vélez Sársfield 3–3 Guadalajara on points. Guadalajara advanced on goal difference.
Libertad | 2–1 | Once Caldas |
---|---|---|
Rob. Gamarra 73' (pen.), 89' | Report | Moreno 55' |
Libertad advanced on points 4–1.
Internacional | 2–0 | Banfield |
---|---|---|
Alecsandro 42' Walter 58' | Report |
Internacional 3–3 Banfield on points. Internacional advanced on away goals.
Cruzeiro | 3–1 | Nacional |
---|---|---|
Thiago Ribeiro 7', 22', 42' | Report | Regueiro 51' |
Nacional | 0–3 | Cruzeiro |
---|---|---|
Report | Thiago Ribeiro 29' Diego Renan 48' Gilberto 80' |
Cruzeiro advanced on points 6–0.
Universidad de Chile | 2–2 | Alianza Lima |
---|---|---|
Vargas 63' Seymour 90+2' | Report | Fernández 24', 87' |
Universidad de Chile advanced on points 4–1.
Teams | Scores | Tie-breakers | |||||
---|---|---|---|---|---|---|---|
Team #1 | Points | Team #2 | 1st leg | 2nd leg | GD | AG | Pen. |
Universidad de Chile | 3:3 | Flamengo | 3–2 | 1–2 | 0:0 | 3:2 | — |
São Paulo | 6:0 | Cruzeiro | 2–0 | 2–0 | — | — | — |
Estudiantes | 3:3 | Internacional | 0–1 | 2–1 | 0:0 | 0:1 | — |
Libertad | 3:3 | Guadalajara | 0–3 | 2–0 | −1:+1 | — | — |
Flamengo | 2–3 | Universidad de Chile |
---|---|---|
Adriano 39' Juan 88' | Report | Victorino 4' Olarra 24' Fernández 47' |
Universidad de Chile | 1–2 | Flamengo |
---|---|---|
Montillo 73' | Report | Vágner Love 45' Adriano 78' |
Universidad de Chile 3–3 Flamengo on points. Universidad de Chile advanced on away goals.
Cruzeiro | 0–2 | São Paulo |
---|---|---|
Report | Dagoberto 23' Hernanes 65' |
São Paulo | 2–0 | Cruzeiro |
---|---|---|
Hernanes 23' Dagoberto 53' | Report |
São Paulo advanced on points 6–0.
Internacional | 1–0 | Estudiantes |
---|---|---|
Sorondo 88' | Report |
Estudiantes | 2–1 | Internacional |
---|---|---|
González 19' Pérez 21' | Report | Giuliano 88' |
Estudiantes 3–3 Internacional on points. Internacional advanced on away goals.
Guadalajara | 3–0 | Libertad |
---|---|---|
Bravo 7', 80' Vázquez 29' | Report |
Libertad | 2–0 | Guadalajara |
---|---|---|
Román 20' Maciel 68' | Report |
Libertad 3–3 Guadalajara on points. Guadalajara advanced on goal difference.
Teams | Scores | Tie-breakers | |||||
---|---|---|---|---|---|---|---|
Team #1 | Points | Team #2 | 1st leg | 2nd leg | GD | AG | Pen. |
Universidad de Chile | 1:4 | Guadalajara | 1–1 | 0–2 | — | — | — |
São Paulo | 3:3 | Internacional | 0–1 | 2–1 | 0:0 | 0:1 | — |
Guadalajara | 1–1 | Universidad de Chile |
---|---|---|
Arellano 52' | Report | Olarra 47' |
Universidad de Chile | 0–2 | Guadalajara |
---|---|---|
Report | Báez 22' Magallón 55' |
Guadalajara advanced 4–1 on points.
Internacional | 1–0 | São Paulo |
---|---|---|
Giuliano 68' | Report |
São Paulo | 2–1 | Internacional |
---|---|---|
Alex Silva 30' Ricardo Oliveira 54' | Report | Alecsandro 52' |
São Paulo 3–3 Internacional on points. Internacional advanced on away goals.
Guadalajara | 1–2 | Internacional |
---|---|---|
Bautista 45+2' | Report | Giuliano 72' Bolívar 76' |
Internacional | 3–2 | Guadalajara |
---|---|---|
Rafael Sóbis 61' Leandro Damião 76' Giuliano 89' | Report | Fabián 43' Bravo 90+2' |
Internacional won the Copa Libertadores on points 6-0.
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