| Doubles | |
|---|---|
| 2016 Città di Como Challenger | |
| Champions |  Roman Jebavý  Andrej Martin |
| Runners-up |  Nils Langer  Gerald Melzer |
| Score | 3–6, 6–1, [10–5] |
Gero Kretschmer and Alexander Satschko were the defending champions but chose not to defend their title.
Roman Jebavý and Andrej Martin won the title after defeating Nils Langer and Gerald Melzer 3–6, 6–1, [10–5] in the final.
James Cerretani / Philipp Oswald (semifinals)
Aliaksandr Bury / Andrei Vasilevski (quarterfinals)
Alessandro Motti / 
Peng Hsien-yin (quarterfinals) Roman Jebavý / Andrej Martin (champions)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | J Cerretani P Oswald | 6 | 68 | [10] | |||||||||||||||||||||||
 A Behar  M Trungelliti | 0 | 710 | [8] | 1 | J Cerretani P Oswald | 7 | 6 | ||||||||||||||||||||
A Arnaboldi  D Marcan | 77 | 77 | A Arnaboldi D Marcan | 5 | 4 | ||||||||||||||||||||||
 I Arvidsson M Cecchinato | 63 | 65 | 1 | J Cerretani P Oswald | 2 | 5 | |||||||||||||||||||||
| 4 | R Jebavý A Martin | 6 | 6 | 4 | R Jebavý A Martin | 6 | 7 | ||||||||||||||||||||
| K Krawietz D Novak | 4 | 2 | 4 | R Jebavý A Martin | w/o | ||||||||||||||||||||||
| WC | Fabio Grassi Massimo Scotti | 0 | 0 |  A Rublev E Ymer | |||||||||||||||||||||||
| A Rublev E Ymer | 6 | 6 | 4 | R Jebavý A Martin | 3 | 6 | [10] | ||||||||||||||||||||
P Cachin  R Carballés Baena | 4 | 63 | N Langer G Melzer | 6 | 1 | [5] | |||||||||||||||||||||
| N Langer G Melzer | 6 | 77 | N Langer G Melzer | 6 | 6 | ||||||||||||||||||||||
| U Ignatik T-h Yang | 4 | 7 | [8] | 3 | A Motti H-y Peng | 3 | 4 | ||||||||||||||||||||
| 3 | A Motti H-y Peng | 6 | 5 | [10] | N Langer G Melzer | 6 | 6 | ||||||||||||||||||||
| WC | S Napolitano A Pellegrino | 6 | 6 | WC | S Napolitano A Pellegrino | 3 | 2 | ||||||||||||||||||||
| WC | L Sonego A Vavassori | 2 | 4 | WC | S Napolitano A Pellegrino | 6 | 65 | [10] | |||||||||||||||||||
R Ghedin  R Ramanathan | 4 | 64 | 2 | A Bury A Vasilevski | 4 | 77 | [7] | ||||||||||||||||||||
| 2 | A Bury A Vasilevski | 6 | 77 | ||||||||||||||||||||||||
Brydan Klein won this event. He defeated Jonathan Eysseric 6–2, 4–6, 6–1 in the final.
Kellen Damico and Nathaniel Schnugg were the defending champions but Schnugg did not compete. Damico partnered with Jonathan Eysseric but lost in the second round to Roman Jebavý and Martin Kližan.
Andrey Kuznetsov and Adrián Menéndez-Maceiras were the defending champions, but they did not participate this year.
Roman Jebavý and Jaroslav Pospíšil were the defending champions, but Pospíšil did not participate this year. Jebavý played alongside Jan Šátral, but they lost in quarterfinals to Lubomír Majšajdr and Martin Zahrádka.
Roman Jebavý and Jan Šátral were the defending champions but lost in the first round to Lukáš Dlouhý and Andrej Martin.
Andrej Martin and Igor Zelenay were the defending champions but only Zelenay returned, partnering Hans Podlipnik. Zelenay lost in the semifinals to Andre Begemann and Aliaksandr Bury.
Íñigo Cervantes and Mark Vervoort were the defending champions but chose not to defend their title.
Laurynas Grigelis and Mohamed Safwat were the defending champions but chose not to defend their title.
Ruben Bemelmans and Philipp Petzschner were the defending champions but chose not to defend their title.
Roman Jebavý and Andrej Martin were the defending champions but chose not to defend their title.
Dominic Inglot and Henri Kontinen were the defending champions, but Kontinen chose not to participate this year. Inglot played alongside Daniel Nestor, but lost in the quarterfinals to Roman Jebavý and Matwé Middelkoop.
Graeme Dyce and Harri Heliövaara won the title by defeating Stephen Donald and Rupesh Roy 6–2, 6–7(4–7), 6–3 in the final.
Jesse Levine and Michael Shabaz were the defending champions, but both players were no longer eligible to compete in the juniors.
Roman Jebavý and Zdeněk Kolář were the defending champions but only Kolář chose to defend his title, partnering Aldin Šetkić. Kolář lost in the first round to Nikola Čačić and Luca Margaroli.
Andrés Molteni and Horacio Zeballos were the defending champions, but chose not to participate together. Molteni played alongside Roman Jebavý, but lost in the quarterfinals to Marco Cecchinato and Dušan Lajović.
Roman Jebavý and Andrés Molteni were the defending champions, but chose not to participate together. Jebavý played alongside Matwé Middelkoop but lost in the semifinals to Philipp Oswald and Filip Polášek. Molteni partnered Leonardo Mayer but lost in the first round to Oliver Marach and Jürgen Melzer.
Denys Molchanov and Igor Zelenay were the defending champions but chose to defend their title with different partners. Molchanov partnered Hans Podlipnik Castillo but lost in the quarterfinals to Jebavý and Zelenay. Zelenay partnered Roman Jebavý but lost in the final to Frederik Nielsen and Tim Pütz.
Austin Krajicek and Franko Škugor were the defending champions, but Krajicek chose to compete at the Summer Olympics and Škugor chose not to defend his title.
Aleksandr Nedovyesov and Gonçalo Oliveira were the defending champions but chose not to defend their title.
Roman Jebavý and Igor Zelenay were the defending champions but only Jebavý chose to defend his title, partnering Adam Pavlásek. Jebavý lost in the final to Neil Oberleitner and Philipp Oswald.