| Singles | |
|---|---|
| 2016 Karshi Challenger | |
| Champion |  Marko Tepavac |
| Runner-up |  Dudi Sela |
| Final score | 2–6, 6–3, 7–6(7–4) |
Teymuraz Gabashvili was the defending champion but chose not to participate.
Marko Tepavac won the title after defeating Dudi Sela 2–6, 6–3, 7–6(7–4) in the final.
Dudi Sela (final)
Karen Khachanov (quarterfinals)
Radu Albot (semifinals)
Aleksandr Nedovyesov (second round) Amir Weintraub (first round)
Denys Molchanov (first round) Dmitry Popko (quarterfinals) Aslan Karatsev (second round)| Semifinals | Final | ||||||||||||
| 1 | Dudi Sela | 6 | 6 | ||||||||||
| 3 | Radu Albot | 4 | 4 | ||||||||||
| 1 | Dudi Sela | 6 | 3 | 64 | |||||||||
| Marko Tepavac | 2 | 6 | 77 | ||||||||||
 Ilya Ivashka | 4 | 6 | 5 | ||||||||||
| Marko Tepavac | 6 | 3 | 7 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | D Sela | 6 | 2 | ||||||||||||||||||||||||
| Q | S Betov | 1 | 1r | 1 | D Sela | 6 | 6 | ||||||||||||||||||||
| WC |  Pavel Tsoy | 1 | 3 | N Milojević | 1 | 2 | |||||||||||||||||||||
| N Milojević | 6 | 6 | 1 | D Sela | 65 | 77 | 6 | ||||||||||||||||||||
 A Velotti | 6 | 6 | 7 | D Popko | 77 | 63 | 4 | ||||||||||||||||||||
| Q | D Matsukevich | 1 | 4 | A Velotti | 6 | 5 | 4 | ||||||||||||||||||||
| Q |  Francesco Vilardo | 3 | 6 | 64 | 7 | D Popko | 4 | 7 | 6 | ||||||||||||||||||
| 7 | D Popko | 6 | 1 | 77 | 1 | D Sela | 6 | 6 | |||||||||||||||||||
| 3 | R Albot | 77 | 6 | 3 | R Albot | 4 | 4 | ||||||||||||||||||||
| WC | S Fayziev | 63 | 4 | 3 | R Albot | 6 | 6 | ||||||||||||||||||||
 C Zampieri | 2 | 64 |  N Barrientos | 0 | 1 | ||||||||||||||||||||||
| N Barrientos | 6 | 77 | 3 | R Albot | 77 | 2 | 6 | ||||||||||||||||||||
 L Harris | 7 | 3 | 3 | M Dubarenco | 62 | 6 | 0 | ||||||||||||||||||||
| M Dubarenco | 5 | 6 | 6 | M Dubarenco | 6 | 6 | |||||||||||||||||||||
 A Bossel | 4 | 6 | 3 | 8 | A Karatsev | 1 | 2 | ||||||||||||||||||||
| 8 | A Karatsev | 6 | 4 | 6 | |||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 6 | D Molchanov | 67 | 2 | ||||||||||||||||||||||||
| Q | R Muzaev | 79 | 6 | Q | R Muzaev | 1 | 4 | ||||||||||||||||||||
 S Diez | 6 | 79 | S Diez | 6 | 6 | ||||||||||||||||||||||
 S Griekspoor | 2 | 67 | S Diez | 3 | 1 | ||||||||||||||||||||||
| WC | T Ismailov | 5 | 4 | I Ivashka | 6 | 6 | |||||||||||||||||||||
| I Ivashka | 7 | 6 | I Ivashka | 6 | 3 | 6 | |||||||||||||||||||||
 E López-Pérez | 3 | 6 | 3 | 4 | A Nedovyesov | 3 | 6 | 2 | |||||||||||||||||||
| 4 | A Nedovyesov | 6 | 4 | 6 | I Ivashka | 4 | 6 | 5 | |||||||||||||||||||
| 5 | A Weintraub | 4 | 2 | M Tepavac | 6 | 3 | 7 | ||||||||||||||||||||
| A Bega | 6 | 6 | A Bega | 5 | 4 | ||||||||||||||||||||||
 T-h Yang | 3 | 1 | M Tepavac | 7 | 6 | ||||||||||||||||||||||
| M Tepavac | 6 | 6 | M Tepavac | 77 | 6 | ||||||||||||||||||||||
| WC | Shonigmatjon Shofayziyev | 78 | 2 | 62 | 2 | K Khachanov | 65 | 4 | |||||||||||||||||||
| LL |  S Barry | 66 | 6 | 77 | LL | S Barry | 1 | 4 | |||||||||||||||||||
 A Metreveli | 2 | 2 | 2 | K Khachanov | 6 | 6 | |||||||||||||||||||||
| 2 | K Khachanov | 6 | 6 | ||||||||||||||||||||||||
Ivo Karlović was the defending champion, but chose not to participate that year.
Fernando González was the defending champion, but lost in the quarterfinals to Björn Phau.
Steve Darcis was the defending champion, but lost in the first round to Andy Roddick, who went on to win the title by defeating Radek Štěpánek in the final, 7–5, 7–5.
Nikolay Davydenko was the defending champion, but chose not to participate that year due to a left heel injury.
Gilles Simon was the defending champion, but chose not to participate that year.
Marcos Baghdatis was the defending champion, but chose to compete in ATP 500 in Washington instead.
Dudi Sela won the title, defeating Ričardas Berankis 7–5, 6–2 in the finals.
Lim Yong-kyu was the defending champion, but lost to Greg Jones in the 2nd round.
Dudi Sela defeated Tatsuma Ito 6–2, 6–7(5), 6–3 in the final match.
Lukáš Rosol was the defending champion but lost in the quarterfinals.
Horacio Zeballos won the title 1–6, 6–4, 7–6(8–6) in the final against Martin Kližan.
Dudi Sela was the defending champion, but he lost in the quarterfinals to Grega Žemlja.
Grega Žemlja won the title defeating Karol Beck in the final 7–6(7–3), 4–6, 6–4.
Cedrik-Marcel Stebe was the defending champion but chose to participate at the 2012 US Open instead.
Dudi Sela won the final 6–1, 7–5 against Yuichi Sugita.
Novak Djokovic was the defending champion, but lost in the fourth round to Tommy Haas. This championship was the first since the tournament's inception that no American was featured in the quarterfinals, with the last player from the US, Sam Querrey, beaten in the fourth round by Tomas Berdych. This meant that it was also the first all-European final eight at the Miami Masters.
Tatsuma Ito was the defending champion, but lost to Dudi Sela in the quarterfinals.
Sela went on to win the title by defeating Alex Bogomolov Jr. 6–1, 6–4 in the final.
Uladzimir Ignatik was the defending champion, but lost to Radu Albot in the first round.
Dudi Sela won the title defeating Teymuraz Gabashvili in the final 6–1, 6–2.
Jarkko Nieminen was the defending champion, but he lost in the first round to Jürgen Zopp, who won the title, defeating Dudi Sela in the final, 6–4, 5–7, 7–6(8–6).
This is the first edition of the tournament.
Ivo Karlović was the defending champion from when the tournament was last held in 2008, but chose not to participate.
Rajeev Ram was the defending champion, but lost in the second round to Dudi Sela.
Dudi Sela was the defending champion but lost in the first round to Hugo Grenier.
Maverick Banes was the defending champion but lost in the first round to Shintaro Imai.
Dudi Sela was the defending champion but chose not to defend his title.