Julien Benneteau and Édouard Roger-Vasselin were the defending champions, but Benneteau withdrew from the tournament because of a sports hernia. Roger-Vasselin played alongside Guillermo García-López, but lost in the third round to Ivan Dodig and Marcelo Melo.
Vasek Pospisil and Jack Sock were the defending champions, but lost in the third round to Jamie Murray and John Peers. Jean-Julien Rojer and Horia Tecău won the title by defeating Murray and Peers in the final by a score of 7–6(7–5), 6–4, 6–4.
Bob and Mike Bryan were the defending champions, but lost to Steve Johnson and Sam Querrey in the first round, making their earliest exit in Grand Slam since 2000 Wimbledon Championships, ending their record streak of winning at least one Grand Slam title every year for the previous 10 years.
Simone Bolelli and Fabio Fognini were the defending champions, but lost in the second round to Adrian Mannarino and Lucas Pouille.
Vasek Pospisil and Jack Sock were the defending champions, but lost in the final to Pierre-Hugues Herbert and Nicolas Mahut, 3–6, 6–7(5–7).
Pablo Cuevas and David Marrero were the defending champions, but Marrero chose not to participate this year. Cuevas played alongside Marcel Granollers, but lost in the quarterfinals to Vasek Pospisil and Jack Sock.
Bob and Mike Bryan won the title, defeating Pospisil and Sock in the final, 2–6, 6–3, [10–7].
Jean-Julien Rojer and Horia Tecău were the defending champions, but lost in the first round to Jonathan Marray and Adil Shamasdin.
Pierre-Hugues Herbert and Nicolas Mahut were the defending champions, but lost in the semifinals to Jamie Murray and Bruno Soares.
Ivan Dodig and Marcelo Melo were the defending champions, but Dodig chose not to participate this year. Melo played alongside Vasek Pospisil, but lost to John Peers and Henri Kontinen in the semifinals.
Pierre-Hugues Herbert and Nicolas Mahut were the defending champions, but lost in the second round to Novak Djokovic and Viktor Troicki.
Pierre-Hugues Herbert and Nicolas Mahut were the defending champions, but withdrew before their second round match due to Herbert's leg injury.
Pierre-Hugues Herbert and Nicolas Mahut were the defending champions, but lost in the semifinals to Feliciano López and Marc López.
Bob and Mike Bryan were the defending champions, but lost in the semifinals to Pierre-Hugues Herbert and Nicolas Mahut.
Pierre-Hugues Herbert and Nicolas Mahut were the defending champions, but lost in the second round to Jay Clarke and Marcus Willis.
Henri Kontinen and John Peers were the defending champions, but lost in the quarterfinals to Ivan Dodig and Marcel Granollers.
Ivan Dodig and Marcel Granollers were the defending champions, but Granollers chose not to participate this year. Dodig played alongside Rajeev Ram, but lost in the semifinals to Pierre-Hugues Herbert and Nicolas Mahut.
Pierre-Hugues Herbert and Nicolas Mahut won the men's doubles tennis title at the 2018 French Open, defeating Oliver Marach and Mate Pavić in the final, 6–2, 7–6(7–4). Herbert and Mahut were the third all-French team to reach the French Open men's doubles final in six years.
Juan Sebastián Cabal and Robert Farah won their second consecutive Grand Slam men's doubles title, defeating Marcel Granollers and Horacio Zeballos in the final, 6–4, 7–5 to win the men's doubles tennis title at the 2019 US Open. Cabal and Farah retained the ATP no. 1 doubles ranking. Mike Bryan, Łukasz Kubot and Nicolas Mahut were also in contention for the top ranking at the start of the tournament.
Marcel Granollers and Rajeev Ram were the defending champions, but chose to compete with different partners. Granollers played alongside Horacio Zeballos, but lost in the second round to Jamie Murray and Neal Skupski. Ram teamed up with Joe Salisbury, but lost in the quarterfinals to Ivan Dodig and Filip Polášek.
Nicolas Mahut and Pierre-Hugues Herbert defeated Alexander Bublik and Andrey Golubev in the final, 4–6, 7–6(7–1), 6–4, to win the men's doubles title at the 2021 French Open. It was their second French Open title and fifth major title together. They saved match points in their semifinal match against Juan Sebastián Cabal and Robert Farah. Bublik and Golubev became the first male Kazakh players to reach a major final.
Ivan Dodig 
Marcel Granollers 
Wesley Koolhof 
