| Men's singles | |
|---|---|
| 2018 Eastbourne International | |
| Champion |  Mischa Zverev |
| Runner-up |  Lukáš Lacko |
| Final score | 6–4, 6–4 |
| Draw | 28 (4 Q / 3 WC ) |
| Seeds | 8 |
Novak Djokovic was the defending champion, but chose not to participate this year.
Mischa Zverev won his first ATP singles title, defeating Lukáš Lacko in the final, 6–4, 6–4.
The top four seeds received a bye into the second round.
Diego Schwartzman (second round)
Kyle Edmund (quarterfinals)
Denis Shapovalov (quarterfinals)
Marco Cecchinato (semifinals) Leonardo Mayer (second round)
David Ferrer (second round)
Steve Johnson (second round)
Márton Fucsovics (withdrew due to hip injury)| Semifinals | Final | ||||||||||||
| Lukáš Lacko | 6 | 6 | |||||||||||
| 4 | Marco Cecchinato | 3 | 4 | ||||||||||
| Lukáš Lacko | 4 | 4 | |||||||||||
| Mischa Zverev | 6 | 6 | |||||||||||
| Mischa Zverev | 711 | 6 | |||||||||||
 Mikhail Kukushkin | 69 | 4 | |||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | D Schwartzman | 6 | 4 | 5 | |||||||||||||||||||||||
| Q |  R Quiroz | 4 | 62 | L Lacko | 4 | 6 | 7 | ||||||||||||||||||||
| L Lacko | 6 | 77 | L Lacko | 6 | 6 | ||||||||||||||||||||||
| LL | J Clarke | 6 | 6 | WC | C Norrie | 3 | 4 | ||||||||||||||||||||
| R Harrison | 4 | 1 | LL | J Clarke | 4 | 3 | |||||||||||||||||||||
| WC | C Norrie | 7 | 64 | 6 | WC | C Norrie | 6 | 6 | |||||||||||||||||||
| Q | D Brands | 5 | 77 | 2 | L Lacko | 6 | 6 | ||||||||||||||||||||
| 4 | M Cecchinato | 3 | 4 | ||||||||||||||||||||||||
| 4 | M Cecchinato | 4 | 6 | 7 | |||||||||||||||||||||||
| A Seppi | 3 | 77 | 64 |  D Istomin | 6 | 4 | 5 | ||||||||||||||||||||
| D Istomin | 6 | 64 | 77 | 4 | M Cecchinato | 5 | 6 | 6 | |||||||||||||||||||
 G Müller | 77 | 3 | 2 |  J Millman | 7 | 3 | 2 | ||||||||||||||||||||
| J Millman | 65 | 6 | 6 | J Millman | 79 | 77 | |||||||||||||||||||||
 G Simon | 4 | 64 | 5 | L Mayer | 67 | 64 | |||||||||||||||||||||
| 5 | L Mayer | 6 | 77 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 7 | S Johnson | 6 | 6 | ||||||||||||||||||||||||
 D Medvedev | 2 | 4 | 7 | S Johnson | 3 | 3 | |||||||||||||||||||||
 N Jarry | 6 | 1 | 4 | M Zverev | 6 | 6 | |||||||||||||||||||||
| M Zverev | 3 | 6 | 6 | M Zverev | 6 | 6 | |||||||||||||||||||||
| J Donaldson | 68 | 6 | 77 | 3 | D Shapovalov | 3 | 3 | ||||||||||||||||||||
| T Fritz | 710 | 3 | 63 | J Donaldson | 4 | 6 | 2 | ||||||||||||||||||||
| 3 | D Shapovalov | 6 | 4 | 6 | |||||||||||||||||||||||
| M Zverev | 711 | 6 | |||||||||||||||||||||||||
| 6 | D Ferrer | 7 | 6 | M Kukushkin | 69 | 4 | |||||||||||||||||||||
| Q | M Berrettini | 5 | 3 | 6 | D Ferrer | 2 | 0 | ||||||||||||||||||||
| M Kukushkin | 6 | 6 | M Kukushkin | 6 | 6 | ||||||||||||||||||||||
| Q | A de Minaur | 1 | 2 | M Kukushkin | 5 | 6 | 6 | ||||||||||||||||||||
| WC |  S Wawrinka | 1 | 3 | 2 | K Edmund | 7 | 3 | 1 | |||||||||||||||||||
| WC | A Murray | 6 | 6 | WC | A Murray | 4 | 4 | ||||||||||||||||||||
| 2 | K Edmund | 6 | 6 | ||||||||||||||||||||||||
Jack Sock (first round) Alex de Minaur (qualified) Matteo Berrettini (qualified) Jay Clarke (qualifying competition, lucky loser) Ivan Nedelko (first round) Roberto Quiroz (qualified) Jan Choinski (first round) Matteo Viola (qualifying competition)| First round | Qualifying competition | ||||||||||||
| 1/Alt | Jack Sock | 4 | 64 | ||||||||||
| Daniel Brands | 6 | 77 | |||||||||||
| Daniel Brands | 64 | 77 | 6 | ||||||||||
| Alessandro Bega | 77 | 62 | 3 | ||||||||||
| Alessandro Bega | 7 | 6 | |||||||||||
| 5 | Ivan Nedelko | 5 | 0 | ||||||||||
| First round | Qualifying competition | ||||||||||||
| 2 | Alex de Minaur | 6 | 6 | ||||||||||
| WC | Jonathan Gray | 1 | 3 | ||||||||||
| 2 | Alex de Minaur | 6 | 6 | ||||||||||
| 8 | Matteo Viola | 2 | 4 | ||||||||||
| Andrew Whittington | 6 | 4 | 2 | ||||||||||
| 8 | Matteo Viola | 4 | 6 | 6 | |||||||||
| First round | Qualifying competition | ||||||||||||
| 3 | Matteo Berrettini | 6 | 6 | ||||||||||
| Andrea Basso | 3 | 3 | |||||||||||
| 3 | Matteo Berrettini | 6 | 77 | ||||||||||
| Carlos Gómez-Herrera | 2 | 63 | |||||||||||
| Carlos Gómez-Herrera | 6 | 6 | |||||||||||
| 7 | Jan Choinski | 3 | 4 | ||||||||||
| First round | Qualifying competition | ||||||||||||
| 4/WC | Jay Clarke | 6 | 7 | ||||||||||
 Marek Jaloviec | 4 | 5 | |||||||||||
| 4/WC | Jay Clarke | 78 | 4 | 4 | |||||||||
| 6 | Roberto Quiroz | 66 | 6 | 6 | |||||||||
 Yannick Mertens | 6 | 4 | 3 | ||||||||||
| 6 | Roberto Quiroz | 3 | 6 | 6 | |||||||||
Roman Safiullin was the defending champion, but was ineligible to play.
Oliver Anderson won the title, defeating Jurabek Karimov in the final, 6–2, 1–6, 6–1.
Stan Wawrinka was the defending champion and successfully defended his title, defeating Mischa Zverev in the final, 4–6, 6–3, 6–3.
Pablo Carreño Busta was the defending champion, but lost in the second round to Julien Benneteau.
Juan Martín del Potro defeated the defending champion Roger Federer in the final, 6–4, 6–7(8–10), 7–6(7–2), to win the men's singles title at the 2018 Indian Wells Masters. Del Potro saved three championship points en route to his first ATP Tour Masters 1000 title, having been a runner-up on three previous occasions.
Roger Federer was the defending champion, but lost in the second round to Thanasi Kokkinakis.
Fabio Fognini was the defending champion, but lost in the second round to Jürgen Zopp.
Roberto Bautista Agut was the defending champion, but chose not to participate this year.
Alexander Zverev was the two-time defending champion, but lost to Cristian Garín in the quarterfinals.
Matteo Berrettini was the defending champion, but withdrew with an ankle injury before the tournament began.
This was the first edition of the tournament.
Andy Murray was the defending champion, but this year he decided to participate in the Cologne event instead, where he later withdrew due to hip injury.
Daniil Medvedev defeated Alexander Zverev in the final, 5–7, 6–4, 6–1, to win the singles title at the 2020 Paris Masters.
Lorenzo Sonego was the defending champion but chose not to participate. Alex de Minaur won the title, having defeated in the final Alexander Bublik with the score 2-0 ret.
Matteo Berrettini defeated Aslan Karatsev in the final, 6–1, 3–6, 7–6(7–0), to win the men's singles tennis title at the 2021 Serbia Open.
Matteo Berrettini was the defending champion from when the event was last held in 2019, but could not participate since he was still competing in the 2021 French Open at the beginning of the tournament.
Feliciano López was the defending champion from when the event was last held in 2019, but lost in the second round to Denis Shapovalov.
Alexander Zverev defeated Andrey Rublev in the final, 6–2, 6–3 to win the men's singles title at the 2021 Cincinnati Masters. It was his fifth ATP Tour Masters 1000 title and 17th career singles title on the ATP Tour.
Cameron Norrie defeated Nikoloz Basilashvili in the final, 3–6, 6–4, 6–1 to win the men's singles tennis title at the 2021 Indian Wells Masters. It was his first ATP Tour Masters 1000 title, and he became the first British player to win the title. Basilashvili became the first Georgian player to reach a Masters 1000 final since Alex Metreveli in 1968 and the first player to do so representing Georgia as an independent nation.
Andrey Rublev was the defending champion, but chose to compete in St. Petersburg instead.
Carlos Alcaraz defeated Diego Schwartzman in the final, 6–4, 6–2 to win the singles title at the 2022 Rio Open. Alcaraz became the youngest winner of an ATP Tour 500 event since the category was created in 2009.