| Men's singles | |
|---|---|
| 2018 Open Castilla y León | |
| Champion |  Ugo Humbert |
| Runner-up |  Adrián Menéndez Maceiras |
| Score | 6–3, 6–4 |
Jaume Munar was the defending champion but chose not to defend his title.
Ugo Humbert won the title after defeating Adrián Menéndez Maceiras 6–3, 6–4 in the final.
Sergiy Stakhovsky (first round) Adrián Menéndez Maceiras (final)
Luca Vanni (semifinals) Andrea Arnaboldi (semifinals)
Scott Griekspoor (first round)
Daniel Brands (quarterfinals) Ugo Humbert (champion) Tallon Griekspoor (withdrew)| Semifinals | Final | ||||||||||||
| 7 | Ugo Humbert | 77 | 6 | ||||||||||
| 3 | Luca Vanni | 65 | 4 | ||||||||||
| 7 | Ugo Humbert | 6 | 6 | ||||||||||
| 2 | Adrián Menéndez Maceiras | 3 | 4 | ||||||||||
| 4 | Andrea Arnaboldi | 66 | 65 | ||||||||||
| 2 | Adrián Menéndez Maceiras | 78 | 77 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | S Stakhovsky | 3 | 6 | 65 | |||||||||||||||||||||||
| M Viola | 6 | 2 | 77 | M Viola | 5 | 5 | |||||||||||||||||||||
 R Quiroz | 4 | 6 | 6 | R Quiroz | 7 | 7 | |||||||||||||||||||||
| Carlos Boluda-Purkiss | 6 | 4 | 4 | R Quiroz | 2 | 7 | 67 | ||||||||||||||||||||
 Christopher Heyman | 4 | 4 | 7 | U Humbert | 6 | 5 | 79 | ||||||||||||||||||||
 João Monteiro | 6 | 6 | J Monteiro | 1 | 3 | ||||||||||||||||||||||
| R Ortega Olmedo | 6 | 3 | 2 | 7 | U Humbert | 6 | 6 | ||||||||||||||||||||
| 7 | U Humbert | 4 | 6 | 6 | 7 | U Humbert | 77 | 6 | |||||||||||||||||||
| 3 | L Vanni | 6 | 4 | 6 | 3 | L Vanni | 65 | 4 | |||||||||||||||||||
| WC | A Davidovich Fokina | 1 | 6 | 4 | 3 | L Vanni | 6 | 3 | 6 | ||||||||||||||||||
| C Gómez-Herrera | 66 | 63 | F Baldi | 4 | 6 | 4 | |||||||||||||||||||||
| F Baldi | 78 | 77 | 3 | L Vanni | 6 | 6 | |||||||||||||||||||||
| GM Moroni | 6 | 6 | GM Moroni | 1 | 4 | ||||||||||||||||||||||
| D Guez | 3 | 2 | GM Moroni | 6 | 61 | 6 | |||||||||||||||||||||
 I Nedelko | 6 | 6 | I Nedelko | 4 | 77 | 3 | |||||||||||||||||||||
| Q |  K-M Maamoun | 3 | 4 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 6 | D Brands | 6 | 6 | ||||||||||||||||||||||||
| Q | A Romero de Ávila Senise | 4 | 2 | 6 | D Brands | 6 | 6 | ||||||||||||||||||||
| Q |  HN Lý | 6 | 6 | Q | HN Lý | 2 | 4 | ||||||||||||||||||||
| LL | S Doumbia | 2 | 1 | 6 | D Brands | 6 | 3 | 65 | |||||||||||||||||||
 T Brkić | 5 | 3 | 4 | A Arnaboldi | 4 | 6 | 77 | ||||||||||||||||||||
| A Šetkić | 7 | 6 | A Šetkić | 3 | 3 | ||||||||||||||||||||||
| WC | Miguel Semmler | 6 | 5 | 5 | 4 | A Arnaboldi | 6 | 6 | |||||||||||||||||||
| 4 | A Arnaboldi | 4 | 7 | 7 | 4 | A Arnaboldi | 66 | 65 | |||||||||||||||||||
| 5 | S Griekspoor | 6 | 1 | 63 | 2 | A Menéndez Maceiras | 78 | 77 | |||||||||||||||||||
| WC | A Artuñedo | 3 | 6 | 77 | WC | A Artuñedo | 6 | 5 | |||||||||||||||||||
 M Neuchrist | 6 | 77 | M Neuchrist | 1 | 2r | ||||||||||||||||||||||
 A Pavić | 3 | 64 | WC | A Artuñedo | 63 | 66 | |||||||||||||||||||||
 C İlkel | 6 | 6 | 2 | A Menéndez Maceiras | 77 | 78 | |||||||||||||||||||||
| WC | Jorge Hernando Ruano | 4 | 3 | C İlkel | 0 | 2 | |||||||||||||||||||||
| Q | Y Jankovits | 4 | 2 | 2 | A Menéndez Maceiras | 6 | 6 | ||||||||||||||||||||
| 2 | A Menéndez Maceiras | 6 | 6 | ||||||||||||||||||||||||
Alessio di Mauro was the defending champion, but lost in the quarterfinals to Víctor Estrella Burgos.
Alejandro Falla was the defending champion, but decided to compete in the 2015 Aircel Chennai Open instead.
Rajeev Ram was the defending champion, but lost in the second round to Daniel Nguyen.
Steve Darcis was the defending champion but decided not to defend his title.
Top seed Adrian Mannarino won his 11th Challenger Tour title, beating Alejandro Falla 5–7, 6–2, 6–2
Gerard Granollers and Adrián Menéndez-Maceiras were the defending champions but only Menéndez-Maceiras defended his title, partnering John Paul Fruttero. Ménendez-Maceiras lost in the first round to Luca Margaroli and Hugo Nys.
Diego Schwartzman was the defending champion, but lost in the semifinals to Marin Čilić.
Purav Raja and Divij Sharan were the defending champions but chose not to defend their title.
Karen Khachanov was the defending champion but lost in the second round to Denis Istomin.
This was the first edition of the tournament.
Viktor Galović was the defending champion but lost in the semifinals to Adrián Menéndez Maceiras.
This was the first edition of the tournament.
Malek Jaziri was the defending champion but chose not to defend his title.
Damir Džumhur was the defending champion, but lost in the quarterfinals to Stan Wawrinka.
Uladzimir Ignatik was the defending champion but lost in the second round to Ugo Humbert.
Quentin Halys was the defending champion but lost in the second round to Dan Evans.
Kevin Anderson was the defending champion, but withdrew before the tournament began because of a right elbow injury.
Marcelo Arévalo was the defending champion but lost in the second round to Marcelo Tomás Barrios Vera.
Filippo Baldi was the defending champion but lost in the third round to Lukáš Lacko.
Jesper de Jong and Vitaliy Sachko were the defending champions but only Sachko chose to defend his title, partnering Vladyslav Manafov.
Luke Saville and John-Patrick Smith were the defending champions but chose not to defend their title.